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City University of New York (CUNY)
Dissertations, Theses, and Capstone Projects
Acquisition; Conditioned Stimuli; Dopamine; Ventral Tegmental Area
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The Role Of The Vta Nmda Receptors, Vta Da Cells And Vta Terminal Regions In Reward-Related Learning, Karen Kest
The Role Of The Vta Nmda Receptors, Vta Da Cells And Vta Terminal Regions In Reward-Related Learning, Karen Kest
Dissertations, Theses, and Capstone Projects
Reward-related learning occurs when an initially neutral stimulus acquires the capacity to elicit responses similar to an unconditioned stimulus (US) with which it is associated, in which case the stimulus now functions as a conditioned stimulus (CS). The mechanisms whereby stimuli come to function as CSs are not fully understood and comprise the theme of this dissertation. We have previously proposed that coincident signals from an unconditioned and the eventual conditioned stimulus (US and CS) signals on dopamine (DA) cells of the ventral tegmental area (VTA) leads to strengthening of CS synapses, allowing the CS to acquire the ability to …