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Effects Of Traumatic Brain Injury On Pediatric Brain Volume, Sanam Jivani Lalani
Effects Of Traumatic Brain Injury On Pediatric Brain Volume, Sanam Jivani Lalani
Theses and Dissertations
This study investigated the effects of lesion presence within larger brain networks (e.g., default mode network (DMN), salience network (SN), and mentalizing network (MN)) in the chronic phase of a pediatric traumatic brain injury (TBI) and the effect on social function. We compared children with a TBI to children with an orthopedic injury (OI) with three different aims. The first aim was to determine whether network volume differed by group (e.g., TBI vs. OI). Second, investigate if lesion presence in a sub component region of the network resulted in total network volume loss for that network. Finally, learn whether network …
A Comparison Of Qualitative And Quantitative White Matter Methods In Pediatric Traumatic Brain Injury, Kacie Larae Wright
A Comparison Of Qualitative And Quantitative White Matter Methods In Pediatric Traumatic Brain Injury, Kacie Larae Wright
Theses and Dissertations
Magnetic resonance imaging is used to assess white matter (WM) abnormalities including total WM volumes and WM hyperintensities (WMHs). Comparisons between several qualitative and quantitative methods to assess WM that are used in research and clinical settings are lacking in pediatric traumatic brain injury (TBI). This study 1) WM methods including Scheltens ratings, manual tracings, NeuroQuant®, and FreeSurfer; (2) compared total WM volumes and WMHs to assess potentially similar reporting of WM integrity; and (3) assessed the relationship between cognitive functions (intelligence, attention, processing speed, and language) and WM in pediatric TBI.Sixty participants (65% male) between ages 8-13 years old, …
Psychiatric Symptom Severity Following Pediatric Traumatic Brain Injury: A Meta-Analysis, Benjamin Douglas Eschler
Psychiatric Symptom Severity Following Pediatric Traumatic Brain Injury: A Meta-Analysis, Benjamin Douglas Eschler
Theses and Dissertations
Objectives: A meta-analysis was conducted to determine the average effect size of internalizing and externalizing symptoms after pediatric traumatic brain injury across a range of severity (mild, moderate, and severe). Two-meta-regressions were also conducted to determine the role of age at injury at time since injury on these effect sizes.Participants and Methods: 9725 titles and abstracts were collected from PubMed, PsycInfo, and Web of Science. Of these, 63 full-text articles were examined for inclusion criteria to determine eligibility for the study. To be included, the studies needed to be published prior to March 2017 in English, needed to have a …
Day-Of-Injury Computed Tomography (Ct) And Longitudinal Rehabilitation Outcomes: A Comparison Of The Marshall And Rotterdam Ct Scoring Methods, Kayla Michelle Alder
Day-Of-Injury Computed Tomography (Ct) And Longitudinal Rehabilitation Outcomes: A Comparison Of The Marshall And Rotterdam Ct Scoring Methods, Kayla Michelle Alder
Theses and Dissertations
Both individual patient-related and injury-related factors predict functional outcomes following moderate-to-severe traumatic brain injury (M/S TBI). Other than binary outcomes such as death, little is known about the role of day-of-injury neuroimaging in predicting long- term outcomes. Classification systems for assessing the severity of injury using computerized tomography (CT) scans, such as the Marshall Classification System (MCS) or Rotterdam scale, have not been systematically studied to see how they relate to long-term rehabilitation and functional outcomes following M/S TBI. The MCS consists of six categories based on information about midline shift, basal cistern compression, surgery evacuation, and lesion size. The …
Psychiatric Symptom Severity Following Pediatric Traumatic Brain Injury: A Meta-Analysis, Benjamin Douglas Eschler
Psychiatric Symptom Severity Following Pediatric Traumatic Brain Injury: A Meta-Analysis, Benjamin Douglas Eschler
Theses and Dissertations
Objectives: A meta-analysis was conducted to determine the average effect size of internalizing and externalizing symptoms after pediatric traumatic brain injury across a range of severity (mild, moderate, and severe). Two-meta-regressions were also conducted to determine the role of age at injury at time since injury on these effect sizes.Participants and Methods: 9725 titles and abstracts were collected from PubMed, PsycInfo, and Web of Science. Of these, 63 full-text articles were examined for inclusion criteria to determine eligibility for the study. To be included, the studies needed to be published prior to March 2017 in English, needed to have a …
A Controlled Comparison Of Errorless And Errorful Learning In Individuals With Moderate-To-Severe Traumatic Brain Injury, Joseph Edward Fair
A Controlled Comparison Of Errorless And Errorful Learning In Individuals With Moderate-To-Severe Traumatic Brain Injury, Joseph Edward Fair
Theses and Dissertations
The prevalence and sequelae of moderate-to-severe (M/S) traumatic brain injury (TBI) are significant and pervasive problems, and effective rehabilitation techniques are key. Errorless learning is regarded as a useful tool for memory impairments; however, the efficacy of errorless learning in a M/S TBI population is unclear. The primary goal (aim 1) of this study was to evaluate the efficacy of a single session of errorless vs. errorful learning in a group of M/S TBI survivors and matched controls. A secondary goal (aim 2) was to investigate the neural time course of errorless learning in participants with M/S TBI by analyzing …
Error Processing And Naturalistic Actions Following Moderate-To-Severe Traumatic Brain Injury, Daniel A. Good
Error Processing And Naturalistic Actions Following Moderate-To-Severe Traumatic Brain Injury, Daniel A. Good
Theses and Dissertations
Moderate-to-severe traumatic brain injury (M/S TBI) can affect an individual's ability to perform daily tasks. For example, individuals with M/S TBI are more likely to commit errors on tasks such as making a meal or wrapping a present. The neural processes involved in such errors are poorly understood. Studies suggest that neurophysiologic markers of cognitive control and error processing may be helpful in gaining additional insight into errors on naturalistic action tasks. Unfortunately, previous experimental methods left a methodological gap which limited the use of neurophysiological markers in the study of naturalistic action. Several recent studies in healthy adults have …
The Neural Systems Of Working Memory: The Sternberg Working Memory Task In A Pediatric Traumatic Brain Injury Sample, Jon Leroy Pertab
The Neural Systems Of Working Memory: The Sternberg Working Memory Task In A Pediatric Traumatic Brain Injury Sample, Jon Leroy Pertab
Theses and Dissertations
Working memory tasks are associated with the activation of widely distributed neural networks. The Sternberg working memory task has been used to explore the neural correlates associated with changes in memory load and the resolution of interference. Preliminary research suggests that the integrity of the anterior cingulate is correlated with resolving load adjustments but not in resolving interference demands; the opposite pattern of associations have been observed with the right middle frontal gyrus.Participants in the present study were 28 children who had sustained moderate to severe traumatic brain injuries (TBI) and 28 children who had sustained orthopedic injuries (OI). Participants …
The Frequency And Severity Of Problem Behaviors Among Individuals With Autism, Traumatic Brain Injury, And Mental Retardation From The Utah Dspd Dataset, Melanie Kay Arp
The Frequency And Severity Of Problem Behaviors Among Individuals With Autism, Traumatic Brain Injury, And Mental Retardation From The Utah Dspd Dataset, Melanie Kay Arp
Theses and Dissertations
The study reports on analyses of data collected from the Inventory for Client and Agency Planning (ICAP) for 5,859 children with Autism (n = 511), Traumatic Brain Injury (TBI, n = 522), or Mental Retardation (MR, n = 4826) whose legal guardians applied for support services through the Utah Department of Services for People with Disabilities (DSPD). Results indicate that the least to most frequent problem behaviors were (a) destructive to property, (b) hurtful to self, (c) hurtful to others, (d) socially offensive, (e) unusual habits, (f) withdrawal, (g) uncooperative, and (h) disruptive behaviors. The degree of severity varied from …