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Association Between C-Reactive Protein And Cognitive Deficits In Elderly Men And Women: A Meta-Analysis, Bruce L. Brown, Dawson W. Hedges, Thomas J. Farrer
Association Between C-Reactive Protein And Cognitive Deficits In Elderly Men And Women: A Meta-Analysis, Bruce L. Brown, Dawson W. Hedges, Thomas J. Farrer
Faculty Publications
Abstract
Background: Certain risk factors for cognitive decline appear modifiable. A potentially modifiable marker of inflammation, C-reactive protein may be associated with cognitive deficits, although not all studies have found a relationship between C-reactive protein and cognitive ability. Further, few research papers have examined whether gender may affect any association between C-reactive protein and cognitive deficit.
Methods: To better understand the association between C-reactive protein, cognitive deficit, and gender in elderly people, we meta-analyzed cross-sectional studies that reported cognitive ability assessed by the Mini-Mental State Examination or an equivalent measure, C-reactive protein concentrations, and gender.
Results: While we identified no …