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Is Animal Assisted Therapy Using Dogs An Effective Treatment For Positive And Negative Symptoms For Adult Inpatient Schizophrenics?, Brian Davidson

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not Animal Assisted Therapy (AAT) using dogs is an effective treatment for positive and negative symptoms for adult inpatient schizophrenics.

STUDY DESIGN: Systematic review of 3 articles published in English in peer reviewed journals between 2005-2009

DATA SOURCES: Two randomized controlled trials and one allocation by minimization controlled trial comparing the effects of AAT using dogs on positive and negative symptoms of schizophrenia to control groups. All articles were found using PubMed and PROQuest

OUTCOMES MEASURED: Focused questionnaires were given before and after …

Identifying Functional Variation In Schizophrenia Gwas Loci By Pooled Sequencing, Erik Loken

Theses and Dissertations

Schizophrenia demonstrates high heritability in part accounted for by common simple nucleotide variants (SNV), rare copy number variants (CNV) and, most recently, rare SNVs Although heritability explained by rare SNVs and CNVs is small compared to that explained by common SNVs, rare SNVs in functional sequences may identify specific disease mechanisms. However, current exome methods do not capture a large proportion of potentially functional bases where rare variation may impact disease risk: as much as two-thirds of conserved sequences lie outside the exome in non-coding regions of cross-species evolutionary constraint. We reasoned that the candidate loci from the Psychiatric Genomics …