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Psychiatry

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Philadelphia College of Osteopathic Medicine

Theses/Dissertations

2017

Schizophrenia

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Is Aristada (Aripiprazole Lauroxil) A Safe And Effective Treatment For Schizophrenia In Adult Patients?, Kyle J. Knowles Jan 2017

Is Aristada (Aripiprazole Lauroxil) A Safe And Effective Treatment For Schizophrenia In Adult Patients?, Kyle J. Knowles

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not “Is Aristada (aripiprazole lauroxil) a safe and effective treatment for schizophrenia in adult patients?”

STUDY DESIGN: Review of three randomized controlled studies. All three trials were conducted between 2014 and 2015.

DATA SOURCES: One randomized, controlled trial and two randomized, controlled, doubleblind trials found via Cochrane Library and PubMed.

OUTCOMES MEASURED: The outcomes that were measured include adverse events (pain at injection site, insomnia, headache, toothache, abdominal discomfort, constipation, diarrhea, akathisia, back pain, dyskinesia, dystonia, nasopharyngitis) measured by vital signs, physical examination, …