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Essential Oils Of Cupressus Funebris, Juniperus Communis, And J. Chinensis (Cupressaceae) As Repellents Against Ticks (Acari: Ixodidae) And Mosquitoes (Diptera: Culicidae) And As Toxicants Against Mosquitoes, John F. Carroll, Nurhayat Tabanca, Matthew H. Kramer, Natasha M. Elejalde, David E. Wedge, Ulrich R. Bernier, Monique Coy, James Becnel, Betul Demirci, Kemal Husnu Can Başer, Jian Zhang, Sui Zhang
Essential Oils Of Cupressus Funebris, Juniperus Communis, And J. Chinensis (Cupressaceae) As Repellents Against Ticks (Acari: Ixodidae) And Mosquitoes (Diptera: Culicidae) And As Toxicants Against Mosquitoes, John F. Carroll, Nurhayat Tabanca, Matthew H. Kramer, Natasha M. Elejalde, David E. Wedge, Ulrich R. Bernier, Monique Coy, James Becnel, Betul Demirci, Kemal Husnu Can Başer, Jian Zhang, Sui Zhang
United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications
Juniperus communis leaf oil, J. chinensis wood oil, and Cupressus funebris wood oil (Cupressaceae) from China were analyzed by gas chromatography and gas chromatography-mass spectrometry. We identified 104 compounds, representing 66.8-95.5% of the oils. The major components were: α-pinene (27.0%), α-terpinene (14.0%), and linalool (10.9%) for J. communis; cuparene (11.3%) and δ-cadinene (7.8%) for J. chinensis; and α-cedrene (16.9%), cedrol (7.6%), and β-cedrene (5.7%) for C. funebris. The essential oils of C. funebris, J. chinensis, and J. communis were evaluated for repellency against adult yellow fever mosquitoes, Aedes aegypti (L.), host-seeking nymphs of the lone …
Novel Carboxamides As Potential Mosquito Repellents, Alan R. Katritzky, Zuoquan Wang, Svetoslav Slavov, Dimitar A. Dobchev, C. Dennis Hall, Maia Tsikolia, Ulrich R. Bernier, Natasha M. Elejalde, Gary G. Clark, Kenneth J. Linthicum
Novel Carboxamides As Potential Mosquito Repellents, Alan R. Katritzky, Zuoquan Wang, Svetoslav Slavov, Dimitar A. Dobchev, C. Dennis Hall, Maia Tsikolia, Ulrich R. Bernier, Natasha M. Elejalde, Gary G. Clark, Kenneth J. Linthicum
United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications
A model was developed using 167 carboxamide derivatives, from the United States Department of Agriculture archival database, that were tested as arthropod repellents over the past 60 yr. An artificial neural network employing CODESSA PRO descriptors was used to construct a quantitative structure-activity relationship model for prediction of novel mosquito repellents. By correlating the structure of these carboxamides with complete protection time, a measure of repellency based on duration, 34 carboxamides were predicted as candidate mosquito repellents. There were four additional compounds selected on the basis of their structural similarity to those predicted. The compounds were synthesized either by reaction …
Eupatorium Capillifolium Essential Oil: Chemical Composition, Antifungal Activity, And Insecticidal Activity, Nurhayat Tabanca, Ulrich R. Bernier, Maia Tsikolia, James Becnel, Blair Sampson, Chris Werle, Betül Demirci, Kemal Hüsnü Can Başer, Eugene K. Blythe, Cecil Pounders, David E. Wedge
Eupatorium Capillifolium Essential Oil: Chemical Composition, Antifungal Activity, And Insecticidal Activity, Nurhayat Tabanca, Ulrich R. Bernier, Maia Tsikolia, James Becnel, Blair Sampson, Chris Werle, Betül Demirci, Kemal Hüsnü Can Başer, Eugene K. Blythe, Cecil Pounders, David E. Wedge
United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications
Natural plant extracts often contain compounds that are useful in pest management applications. The essential oil of Eupatorium capillifolium (dog-fennel) was investigated for antifungal and insecticidal activities. Essential oil obtained by hydrodistillation of aerial parts was analyzed by gas chromatography (GC) and gas chromatography–mass spectrometry (GC/MS). The major components were determined to be thymol methyl ether (=methyl thymol) (36.3%), 2,5-dimethoxy-p-cymene (20.8%) and myrcene (15.7%). Antifungal activity of the essential oil was weak against the plant pathogens Colletotrichum acutatum, C. fragariae, and C. gloeosporioides in direct bioautography assay. The E. capillifolium oil showed promising repellent activity against …
Structure-Activity Relationships Of 33 Carboxamides As Toxicants Against Female Aedes Aegypti (Diptera: Culicidae), Julia Pridgeon, James J. Becnel, Ulrich R. Bernier, Gary G. Clark, Kenneth J. Linthicum
Structure-Activity Relationships Of 33 Carboxamides As Toxicants Against Female Aedes Aegypti (Diptera: Culicidae), Julia Pridgeon, James J. Becnel, Ulrich R. Bernier, Gary G. Clark, Kenneth J. Linthicum
United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications
Aedes aegypti L. is the primary vector of dengue and yellow fever viruses, and use of aerosolized insecticides is one of the primary ways to control this medically important mosquito. However, few new insecticides have been developed for mosquito control in recent years. As a part of our effort to search for new insecticides to control mosquitoes, toxicities of 33 carboxamides were evaluated against female A. aegypti by topical application. This group included nine different categories of compounds, namely benzamides, phenyl-propenamides, propanamides, butanamides, butenamides, pentanamides, pentenamides, hexanamides, and hexenamides, that exhibited varying levels of toxicity against this mosquito species. The …
Toxicity Comparison Of Eight Repellents Against Four Species Of Female Mosquitoes, Julia W. Pridgeon, Ulrich R. Bernier, James J. Becnel
Toxicity Comparison Of Eight Repellents Against Four Species Of Female Mosquitoes, Julia W. Pridgeon, Ulrich R. Bernier, James J. Becnel
United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications
The relative toxicities of 8 repellents (DMP, Rutgers 612, DEET, IR3535, Picardin, PMD, AI3-35765, and AI3-37220) were evaluated by topical application against females of Aedes aegypti, Culex quinquefasciatus, Anopheles quadrimaculatus, and An. albimanus. Based on 24-h LD50 values, the most toxic repellent against all 4 mosquito species was AI3-37220, with values of 0.25, 0.20, 0.16, and 0.11 µg/mg for the listed 4 mosquito species, respectively. The least toxic of the 8 repellents tested was DMP, with LD50 values of 5.40, 4.72, 2.50, and 1.83 µg/mg, respectively. Based on the 24-h LD50 values, An. …
Laboratory And Field Assessment Of Some Kairomone Blends For Host-Seeking Aedes Aegypti, Craig R. Williams, Ramona Bergbauer, Martin Geier, Daniel L. Kline, Ulrich R. Bernier, Richard Russell, Scott A. Ritchie
Laboratory And Field Assessment Of Some Kairomone Blends For Host-Seeking Aedes Aegypti, Craig R. Williams, Ramona Bergbauer, Martin Geier, Daniel L. Kline, Ulrich R. Bernier, Richard Russell, Scott A. Ritchie
United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications
Using laboratory Y-tube olfactometers, the attractiveness of lactic acid and 2 kairomone blends from the United States Department of Agriculture (USDA) and BioGents GmbH (BG) was assessed for attractiveness to Aedes aegypti. Four geographically disparate populations were assessed: North Queensland Australia (NQA), Florida USA, Minas Gerais Brazil (MGB), and Singapore. In descending order, populations were attracted to USE)A, BG blends, and lactic acid. MGB was poorly attracted to lactic acid alone. The blends were less attractive than human odor. Proprietary blends were modified, and their attractiveness was assessed to find the optimum attractive mixture for NQA. Adding acetone to …
Laboratory Evaluation Of Mosquito Traps Baited With A Synthetic Human Odor Blend To Capture Aedes Aegypti, Ivoneide M. Silva, Alvaro E. Eiras, Daniel L. Kline, Ulrich R. Bernier
Laboratory Evaluation Of Mosquito Traps Baited With A Synthetic Human Odor Blend To Capture Aedes Aegypti, Ivoneide M. Silva, Alvaro E. Eiras, Daniel L. Kline, Ulrich R. Bernier
United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications
A synthetic blend of chemicals comprising volatiles released by the human body has been shown to be an effective attractant for female Aedes aegypti in olfactometer bioassays with laboratory-reared mosquitoes. We report the laboratory evaluation of Ae. aegypti response to a synthetic blend tested with 4 types of mosquito traps (CDC model 512, CDC model 1012, CFG, and Fay–Prince traps). Aedes aegypti females were attracted significantly by the blend. The higher release rate of attractant (320.2 ± 10.71 mg/h) more efficiently attracted mosquitoes than the lower release rate (42.0 ± 2.3 mg/h). Although both the Fay–Prince and CFG traps caught …