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Impairing The Insect Immune System With Plant-Derived Substances, Katherine Haszcz

MSU Graduate Theses

Worldwide resistance to current insecticides continues to grow at an alarming rate, with the danger of pesticide overuse reducing acceptable doses. Alternative strategies for insect pest management are therefore imperative. By compromising the insect immune system with plant-derived substances and studying the detailed processes involved in hemocyte-mediated responses, one can develop improved methods for insect control. Hemocyte numbers change in response to stress. This allows essential defense mechanisms such as phagocytosis and encapsulation to take place. In this thesis, plant-derived substances were used to challenge larval-stage Galleria mellonella (Family: Lepidoptera) due to their nontoxic nature and high value in pest …