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Isoflavones In Legumes As Functional Forages And Feeds In Ruminant Grazing Systems, B. E. Davis, Michael D. Flythe, T. A. Hamilton, D. G. Ely, L. H. Anderson, J. R. Weinert-Nelson Feb 2024

Isoflavones In Legumes As Functional Forages And Feeds In Ruminant Grazing Systems, B. E. Davis, Michael D. Flythe, T. A. Hamilton, D. G. Ely, L. H. Anderson, J. R. Weinert-Nelson

IGC Proceedings (1997-2023)

Legumes are often utilized in livestock grazing systems to improve diet quality, diversity, and consequently animal performance. In addition to their nutritional utility, legumes contain phytoestrogenic isoflavones that have selective antimicrobial activity in the rumen and once absorbed can cause arterial vasodilation. These added bioactive functions of isoflavones suggest that legumes could be strategically utilized in grazing systems as functional forages to improve ruminant performance and health. The objective of this presentation will be to discuss past and current research on the application of isoflavones via legumes as an antimicrobial for growth promotion and as a mitigation strategy for fescue …


Antimicrobial Assay Of Sagebrush Roots, Lauren Rachel (Moody) Mcfadden May 2022

Antimicrobial Assay Of Sagebrush Roots, Lauren Rachel (Moody) Mcfadden

Undergraduate Honors Capstone Projects

Plants produce secondary metabolites for various functions, one of which is antibacterial activities. Sagebrush has historically been used by Native Americans for different medicinal purposes, suggesting that it may have secondary metabolites that would have medicinal values, including antimicrobial activities, and can be a natural source for antibiotics. This study aims to carry out the antimicrobial activity of Sagebrush root extract against a handful of bacteria. We tested the antimicrobial activity of root extract of Sagebrush against six bacteria such as Bacillus subtilis, Bacillus cereus, E. coli DHSα (Lab cloning strain), Agrobacterium tumefaciens GV3101 (Lab cloning strain), Pseudomonas …


Genetic Characterization Of Antimicrobial Activities Of Endophytic Bacteria Burkholderia Strains Ms455 And Ms389, Jiayuan Jia Dec 2021

Genetic Characterization Of Antimicrobial Activities Of Endophytic Bacteria Burkholderia Strains Ms455 And Ms389, Jiayuan Jia

Theses and Dissertations

Strains MS455 and MS389, endophytic bacteria, were isolated from healthy soybean plant growing adjacent to a patch of plants affected by charcoal rot disease, caused by the fungal pathogen Macrophomina phaseolina. The complete genomes of both strains were sequenced and identified as Burkholderia species Strain MS455 exhibits broad-spectrum antifungal activities against economically important pathogens, including Aspergillus flavus. Random and site-specific mutations were employed in discovery of the genes that share high homology to the ocf gene cluster of Burkholderia contaminans strain MS14, which is responsible for production of the antifungal compound occidiofungin. RNA-seq analysis demonstrated ORF1, a …


Hemp Growth Factors And Extraction Methods Effect On Antimicrobial Activity Of Hemp Seed Oil: A Systematic Review, Klaudia Ostapczuk, Samuel Obeng Apori, Giovani Estrada, Furong Tian Sep 2021

Hemp Growth Factors And Extraction Methods Effect On Antimicrobial Activity Of Hemp Seed Oil: A Systematic Review, Klaudia Ostapczuk, Samuel Obeng Apori, Giovani Estrada, Furong Tian

Articles

The bioactive Hemp Seed Oil (HSO) is becoming very popular in the medical and research fields due to its antimicrobial properties against several diseases caused by bacteria and fungi. However, the effect of hemp-growing factors and extraction methods on the bioactivity of HSO does not receive adequate research attention. Therefore, this review aims to investigate the effect of growth factors and extraction methods on the antimicrobial activity of HSO. Articles were retrieved from Google Scholar and the Scopus database and screened against inclusion and exclusion criteria. The study revealed that HSO prefers warm climates and favorable humidity ranging from 20 …


Gc-Ms Profiling, Antioxidant, Antimicrobial Activities, Dna Cleavage Effect Ofsymphytum Aintabicum Hub.-Mor. & Wickens (Boraginaceae) And Its Anticancer Activityon Mcf-7 Cell Line, Alevcan Kaplan Jan 2021

Gc-Ms Profiling, Antioxidant, Antimicrobial Activities, Dna Cleavage Effect Ofsymphytum Aintabicum Hub.-Mor. & Wickens (Boraginaceae) And Its Anticancer Activityon Mcf-7 Cell Line, Alevcan Kaplan

Turkish Journal of Botany

Symphytum species, generally known as comfrey, have been used for ancient times in folk medicine for wounds, bone breakages, rheumatism, liver problems, and innumerable potentialities. However, many of the species belonging to the genus Symphytum have not been analyzed with scientific methods and principles yet. Therefore, this work is a guide for determining and researching the main gaps in the literature. In this study, MeOH and petroleum ether (PE) extracts of Symphytum aintabicum Hub.-Mor. & Wickens were analyzed for their biological activities and GC-MS analysis, antioxidant, antimicrobial activities, DNA cleavage effect, and anticancer activity on the MCF-7 human breast cell …


Elucidation Of Multi-Origin Inula Helenium L. For Antimicrobial Activity And Heavy Metal Profiling As An Exemplar For The Use And Regulation Of Plants As Antibiotics., Ciara Ruth Kenny Jan 2021

Elucidation Of Multi-Origin Inula Helenium L. For Antimicrobial Activity And Heavy Metal Profiling As An Exemplar For The Use And Regulation Of Plants As Antibiotics., Ciara Ruth Kenny

Theses

An impending post-antibiotic era looms, thus new sources of therapeutic chemical entities are crucial to sustain effective antimicrobial chemotherapy worldwide. Plant natural products are a source of accessible, structurally diverse compounds that provide therapeutic potential. The pharmacological applications of plants in medicine can be guided by the attestation of traditional use or the application of this knowledge to uncover new leads in the drug discovery process. The range of modified in vitro methods commonly used to investigate preclinical antimicrobial efficacy of plant-derived natural products, and the associated limitations and challenges in the provision of new antimicrobial drugs from plants is …


Exploring The Potential Of Endophytes And Medicinal Plants As Sources Of Antimicrobials To Control Citrus Greening, Jessica Dominguez Jul 2019

Exploring The Potential Of Endophytes And Medicinal Plants As Sources Of Antimicrobials To Control Citrus Greening, Jessica Dominguez

FIU Electronic Theses and Dissertations

Citrus greening is an economically disastrous bacterial disease that infects all species of citrus, and currently has no cure. It is caused by Candidatus Liberibacter asiaticus (CLas), an unculturable phloem-limited bacteria vectored by the sap-sucking insect Diaphorina citri. Citrus greening has spread to every citrus-producing county in Florida; thus, there is a crucial need to develop environmentally safe treatments to reduce or eliminate CLas. It was hypothesized that endophytic microorganisms isolated from survivor citrus trees would show antagonistic activity against CLas; also, that plant extracts with known antimicrobial properties could suppress CLas. Oregano, thyme and turmeric extracts in the …


Screening Of Crude Microalgal Extracts For Antimicrobial Activity, Patrick Matulich May 2019

Screening Of Crude Microalgal Extracts For Antimicrobial Activity, Patrick Matulich

Theses & Dissertations

Microbial biofilm associated infections are a significant threat to patients with medical devices and are partially responsible for the increased resistance seen in nosocomial infections. The biofilm chemical and physical properties restrict access of chemotherapeutic agents. Therefore, there is a need to enhance the antimicrobial effects of current chemotherapeutic agents. Microalgae live in competitive environments that include film-forming, opportunistic pathogens S. maltophilia and C. albicans. Extracts from 5 diverse species of microalgae were screened for antimicrobial enhancing effects against established biofilms with two different extraction solvents, 3:1 hexanes and isopropyl (HIPA) and 2-methyltetrahydrofuran (2-MTHF).

Three species, B. braunii, …


Phaeophleospora Vochysiae Savi & Glienke Sp. Nov. Isolated From Vochysia Divergens Found In The Pantanal, Brazil, Produces Bioactive Secondary Metabolites, Daiani C. Savi, Khaled A. Shaaban, Francielly M. W. Gos, Larissa V. Ponomareva, Jon S. Thorson, Chirlei Glienke, Jürgen Rohr Feb 2018

Phaeophleospora Vochysiae Savi & Glienke Sp. Nov. Isolated From Vochysia Divergens Found In The Pantanal, Brazil, Produces Bioactive Secondary Metabolites, Daiani C. Savi, Khaled A. Shaaban, Francielly M. W. Gos, Larissa V. Ponomareva, Jon S. Thorson, Chirlei Glienke, Jürgen Rohr

Pharmaceutical Sciences Faculty Publications

Microorganisms associated with plants are highly diverse and can produce a large number of secondary metabolites, with antimicrobial, anti-parasitic and cytotoxic activities. We are particularly interested in exploring endophytes from medicinal plants found in the Pantanal, a unique and widely unexplored wetland in Brazil. In a bio-prospecting study, strains LGMF1213 and LGMF1215 were isolated as endophytes from Vochysia divergens, and by morphological and molecular phylogenetic analyses were characterized as Phaeophleospora vochysiae sp. nov. The chemical assessment of this species reveals three major compounds with high biological activity, cercoscosporin (1), isocercosporin (2) and the new compound 3-(sec-butyl)-6-ethyl-4,5-dihydroxy-2-methoxy-6-methylcyclohex-2-enone (3). …


Antibacterial Activity And Chemical Characterization Of Resin From Sciadopitys Verticillata (Thunb.) Siebold And Zuccarini, David Ira Yates Dec 2016

Antibacterial Activity And Chemical Characterization Of Resin From Sciadopitys Verticillata (Thunb.) Siebold And Zuccarini, David Ira Yates

Doctoral Dissertations

Sciadopitys verticillata produces white viscous resin that is unique among the conifers. This research investigated effects of resin on bacteria from different ecological niches and the chemical composition of the resin. Each bacterial species was evaluated separately for response to winter- and summer-collected resins. Exposure to winter-collected resin reduced numbers of colonies of Bacillus cereus, Erwinia amylovora, Agrobacterium tumefaciens, and Escherichia coli and increased numbers of Xanthomonascampestris, Pseudomonas fluorescens, and Pseudomonas syringae. Summer-collected resin affectedpopulation growth of two bacterial species; population counts of E. amylovora decreased and those of P. fluorescens increased. Selected strains of …


Switchgrass Extractives Have Potential As A Value-Added Antimicrobial Against Plant Pathogens And Foodborne Pathogens, Alexander Ian Bruce Dec 2016

Switchgrass Extractives Have Potential As A Value-Added Antimicrobial Against Plant Pathogens And Foodborne Pathogens, Alexander Ian Bruce

Masters Theses

Panicum virgatum (switchgrass), a perennial grass native to North America, is a leading biomass feedstock candidate for the manufacture of cellulosic ethanol. Switchgrass is considered a viable option for biofuel production due to its cheap production cost and ability to grow on marginal land. Biofuel derived from switchgrass has been shown to be very energy efficient, producing 540% more renewable energy versus nonrenewable energy expended. Switchgrass-derived biofuel is also estimated to have greenhouse gas emissions that are 94% lower than emissions from gasoline (Schmer et al 2008). Biofuels are created through biochemical processes that utilize various enzymes and microorganisms for …