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Morphogenesis Is Coordinated With Nuclear Division In Germinating Aspergillus Nidulans Conidiospores, Steven D. Harris
Morphogenesis Is Coordinated With Nuclear Division In Germinating Aspergillus Nidulans Conidiospores, Steven D. Harris
Department of Plant Pathology: Faculty Publications
Germinating Aspergillus nidulans conidiospores switch to polarized apical growth following an initial period of isotropic expansion. At the same time, they re-enter the nuclear division cycle. The relationship between spore polarization and nuclear division was investigated by testing the effect of cell cycle inhibitors and temperature-sensitive cell cycle mutations on spore morphogenesis. On rich media, it was found that spore polarization is delayed if completion of the first mitosis is blocked. The observed delay may be dependent upon the activity of the mitosis-promoting NIMA kinase. An additional mechanism appears to prevent polarization as the spore progresses through its first S …