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Mutations In Pmr5 Result In Powdery Mildew Resistance And Altered Cell Wall Composition, John P. Vogel, Ted K. Raab, Chris R. Somerville, Shauna C. Somerville

Ted K. Raab

Powdery mildews and other obligate biotrophic pathogens are highly adapted to their hosts and often show limited host ranges. One facet of such host specialization is likely to be penetration of the host cell wall, a major barrier to infection. A mutation in the pmr5 gene rendered Arabidopsis resistant to the powdery mildew species Erysiphe cichoracearum and Erysiphe orontii, but not to the unrelated pathogens Pseudomonas syringae or Peronospora parasitica. PMR5 belongs to a large family of plant-specific genes of unknown function. pmr5-mediated resistance did not require signaling through either the salicylic acid or jasmonic acid/ ethylene defense pathways, suggesting …