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Profiling The Action Of Acetylcholine In The Drosophila Melanogaster Larval Model: Heart, Behavior, And The Development And Maintenance Of Sensorimotor Circuits, Cole A. Malloy
Theses and Dissertations--Biology
Understanding the role of various chemical messengers in altering behaviors and physiological processes is a common goal for scientists across multiple disciplines. The main focus of this dissertation is on characterizing the action of an important neurotransmitter, acetylcholine (ACh), modulating larval Drosophila melanogaster neural circuits and heart. In this dissertation, I provide important insights into the mechanisms by which ACh influences the formation and performance of select neural circuits, while also revealing significant details regarding its role in additional physiological functions, including cardiac pace making. In Chapter 1, I provide a general overview of ACh action in mammals and flies …