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Development Of A Two-Photon Imaging System, Jesseca Hollenbaugh
Development Of A Two-Photon Imaging System, Jesseca Hollenbaugh
University Honors Theses
The objective of this project was to convert a Sarastro 2000 confocal laser scanning microscope (CLSM) into a system capable of far-field two-photon excitation (TPE) imaging for the use of the PSU Biology department. TPE microscopy operates on the ability of fluorophores to accept two photons each with half the energy of a desired transition in a single quantum event via a virtual energy state and then emit a higher energy photon upon relaxation. This is preferable to single-photon excitation (SPE) imaging due to lower photon imaging, causing less damage to delicate biological samples, as well as the inherent localization …
Pt-Symmetry And Eigenmodes, Tamara Gratcheva
Pt-Symmetry And Eigenmodes, Tamara Gratcheva
University Honors Theses
Spectra of systems with balanced gain and loss, described by Hamiltonians with parity and time-reversal (PT) symmetry is a rich area of research. This work studies by means of numerical techniques, how eigenvalues and eigenfunctions of a Schrodinger operator change as a gain-loss parameter changes. Two cases on a disk with zero boundary conditions are considered. In the first case, within the enclosing disk, we place a parity (P) symmetric configuration of three smaller disks containing gain and loss media, which does not have PT-symmetry. In the second case, we study a PT-symmetric configuration …
Spectroscopic End Point Detection With An Electron Beam Evaporator, Ryan Mcgraw
Spectroscopic End Point Detection With An Electron Beam Evaporator, Ryan Mcgraw
University Honors Theses
Spectroscopic end point detection is a common tool used for measuring slope changes in wavelength intensity. Using algorithms able to apply this concept, coatings will be able to be dynamically measured in real time and stopped at the appropriate level to ensure process uniformity. It is currently applied to reductive processes such as etching, where the surface will start to be eaten away, creating a plasma. When the entire amount of a material on a substrate has been eaten away, the plasma will change color as it is beginning to etch a different material. Using a spectrometer, this point where …
Multi-Agent Deep Reinforcement Learning For Radiation Localization, Benjamin Scott Totten
Multi-Agent Deep Reinforcement Learning For Radiation Localization, Benjamin Scott Totten
Dissertations and Theses
For the safety of both equipment and human life, it is important to identify the location of orphaned radioactive material as quickly and accurately as possible. There are many factors that make radiation localization a challenging task, such as low gamma radiation signal strength and the need to search in unknown environments without prior information. The inverse-square relationship between the intensity of radiation and the source location, the probabilistic nature of nuclear decay and gamma ray detection, and the pervasive presence of naturally occurring environmental radiation complicates localization tasks. The presence of obstructions in complex environments can further attenuate the …
Uhv-Shear-Force Acoustic Near-Field Microscopy And Its Implementation In The Study Of Confined Mesoscopic Fluids, Theodore Alex Brockman
Uhv-Shear-Force Acoustic Near-Field Microscopy And Its Implementation In The Study Of Confined Mesoscopic Fluids, Theodore Alex Brockman
Dissertations and Theses
The design, construction, and implementation of Shear-force Acoustic Near-Field Microscopy (SANM), operational from ultrahigh vacuum (UHV) to ambient conditions--offering a pristine environment for more reliable characterization the hydrophobic/hydrophilic wetting properties of surfaces--is presented. SANM capitalizes on its sensitivity to the evanescent near-field acoustic emissions from a mesoscopic fluid (confined between the apex of a laterally oscillating tapered nanosized probe and a flat substrate) when subjected to shear motion. This distinct capability provides direct access to the fluid’s viscoelastic response when subjected to shear interactions, in contrast to indirect measurements performed by other standard probe proximity scanning techniques. The entire …
Flash-Rt: Using High-Dose Radiation For Clinical Radiation Therapy, Deja Stubbs
Flash-Rt: Using High-Dose Radiation For Clinical Radiation Therapy, Deja Stubbs
University Honors Theses
This paper is a literature review on the possible mechanisms behind the FLASH effect and why such research can advance the world of radiology treatment by modifying current clinical linear accelerators to produce ultra-high doses of radiation. Radiation Therapy, also known as external Beam Radiation Therapy, is a common type of cancer treatment. Globally, cancer is the second-leading cause of death, but has seen an increase in survival rates over the past couple of years. Cancer can develop in almost any part of the body since cancer is defined as uncontrolled cell growth. The FLASH Effect is seen when treating …
Possibilities For Inertial Electrostatic Confinement Fusion, Jeffrey Edward Black
Possibilities For Inertial Electrostatic Confinement Fusion, Jeffrey Edward Black
Dissertations and Theses
While most of the fusion energy research is focused on magnetic confinement, there have been several alternative confinement methods aimed at the development of smaller and less expensive reactors. A number of these devices utilize a spherically convergent beam of recirculating ions, a technique known as inertial electrostatic confinement (IEC). This study looks at several aspects of IEC devices, including measurements of the fusion rate of an IEC device with a wire mesh electrode cathode, and a solid titanium cathode. In addition, several computational studies were performed to explore the possibilities for IEC fusion. These include development of a 1D-1P …
System Design For The Quantification Of Microbial Motility In Extreme Environments, Megan Marie Dubay
System Design For The Quantification Of Microbial Motility In Extreme Environments, Megan Marie Dubay
Dissertations and Theses
Motility of microorganisms is understudied but provides useful insights into their behavior. Organisms' ability to move autonomously changes how they interact with their environment--finding nutrients, interacting with other organisms, and avoiding unfavorable conditions. Understanding motility features can also be used to identify specific species, such as the identification of Vibrio cholerae in human samples. Motility might also be used as evidence of life existing in even the most extreme environments on Earth, and possibly beyond. Specialized microscopy systems can be required to examine the motility of microorganisms due to the nature of the environments to which the instruments are exposed. …
Characterizing The Single-Photon State: Quantum Physics Experiments With Single-Photon Sensitivity, Sheldon Lee Field
Characterizing The Single-Photon State: Quantum Physics Experiments With Single-Photon Sensitivity, Sheldon Lee Field
University Honors Theses
Coincidence-counting and spontaneous parametric downconversion are central to introductory quantum mechanical experimentation but have remained largely out of reach of undergraduate physics instructors. This thesis summarizes the theory behind light polarization, spontaneous parametric downconversion, birefringent refractive indices, and an affordable self-contained photon coincidence counting unit (CCU). A method for implementing a CCU to demonstrate downconversion is presented, and empirical results are provided.
Methodologies For Quantum Circuit And Algorithm Design At Low And High Levels, Edison Tsai
Methodologies For Quantum Circuit And Algorithm Design At Low And High Levels, Edison Tsai
Dissertations and Theses
Although the concept of quantum computing has existed for decades, the technology needed to successfully implement a quantum computing system has not yet reached the level of sophistication, reliability, and scalability necessary for commercial viability until very recently. Significant progress on this front was made in the past few years, with IBM planning to create a 1000-qubit chip by the end of 2023, and Google already claiming to have achieved quantum supremacy. Other major industry players such as Intel and Microsoft have also invested significant amounts of resources into quantum computing research.
Any viable computing system requires both hardware and …
Observation And Control Of Photoemission And Electric Field Enhancement Of Plasmonic Antennas Through Photoemission Electron Microscopy, Christopher M. Scheffler
Observation And Control Of Photoemission And Electric Field Enhancement Of Plasmonic Antennas Through Photoemission Electron Microscopy, Christopher M. Scheffler
Dissertations and Theses
Photoemission electron microscopy (PEEM) is an imaging method which uses electrons excited through the photoelectric effect to characterize a sample surface with nanometer-level resolution. In PEEM, a high intensity laser excites electrons from the surface of the material and electron optics are used to form an image from the intensity and spatial distribution of the photoemission from the sample. The goal of this research was to study and maximize light confinement, which was accomplished using plasmonic nanostructures. Surface plasmons represent oscillations in the electron density of a material and can occur along the transition interface between a metal and a …
Characterization Of High Mobility Channels For Use In Quantum Computing Devices, Payam Amin
Characterization Of High Mobility Channels For Use In Quantum Computing Devices, Payam Amin
Dissertations and Theses
Quantum computing promises computation that is fundamentally beyond the reach of classical computers. For the realization of a full-scale quantum computer, millions of quantum bits need to be fabricated on an integrated circuit and operated at cryogenic temperatures. Silicon and silicon-germanium based electron spin quantum bits have the advantage of leveraging decades of semiconductor industry knowledge for high volume manufacturability.
During the process development of any semiconductor device, material characterization is essential to understand and improve the process. Transmission electron microscopy is the only technique that could offer localized high spatial resolution characterization. In this work we have introduced two …
Effects Of Pore-Forming Peptides (Melittin And Magainin 2) On The Phospholipid Bilayer Interior, Elmukhtar Ehmed Alhatmi
Effects Of Pore-Forming Peptides (Melittin And Magainin 2) On The Phospholipid Bilayer Interior, Elmukhtar Ehmed Alhatmi
Dissertations and Theses
Antimicrobial peptides (AMPs) are one of the most promising solutions to drug-resistant bacteria. Melittin and magainin 2 are two of the most representative and extensively studied AMPs. In this research, I investigated the interaction of these two AMPs with three models of cell membranes: 80% POPC 20% POPG, 40%POPC 40% POPE and 20% POPG, and 80%POPC 20%POPG plus 30% mole fraction of cholesterol. Time-resolved fluorescence emission and fluorescence anisotropy decays of the fluorescent probe 1,6-diphenyl-1,3,5-hexatriene (DPH) were analyzed to determine the effects of AMPs on the bilayer headgroup packing and changes in the interior of the phospholipid bilayer during the …
Quantum Field Theories, Topological Materials, And Topological Quantum Computing, Muhammad Ilyas
Quantum Field Theories, Topological Materials, And Topological Quantum Computing, Muhammad Ilyas
Dissertations and Theses
A quantum computer can perform exponentially faster than its classical counterpart. It works on the principle of superposition. But due to the decoherence effect, the superposition of a quantum state gets destroyed by the interaction with the environment. It is a real challenge to completely isolate a quantum system to make it free of decoherence. This problem can be circumvented by the use of topological quantum phases of matter. These phases have quasiparticles excitations called anyons. The anyons are charge-flux composites and show exotic fractional statistics. When the order of exchange matters, then the anyons are called non-Abelian anyons. Majorana …
The Return To Anisotropy Across A Jet In Crossflow, Gregory P. Sakradse
The Return To Anisotropy Across A Jet In Crossflow, Gregory P. Sakradse
Dissertations and Theses
With data from experiments on a jet of air emitting from an orifice flush with the floor of a wind tunnel providing a transverse flow, analysis is conducted to extract information about the state of anisotropy in the Reynolds stress tensor. Inflow velocities are modulated across two distinct turbulence intensity regimes while holding jet exit conditions constant, providing an opportunity to isolate effects of both jet to crossflow velocity ratio, r and the effects of the turbulence carried by the crossflow. Anisotropy in the Reynolds stress tensor is examined through anisotropy invariant maps and evolution of the function F, …
Efficient Neuromorphic Algorithms For Gamma-Ray Spectrum Denoising And Radionuclide Identification, Merlin Phillip Carson
Efficient Neuromorphic Algorithms For Gamma-Ray Spectrum Denoising And Radionuclide Identification, Merlin Phillip Carson
Dissertations and Theses
Radionuclide detection and identification are important tasks for deterring a potentially catastrophic nuclear event. Due to high levels of background radiation from both terrestrial and extraterrestrial sources, some form of noise reduction pre-processing is required for a gamma-ray spectrum prior to being analyzed by an identification algorithm so as to determine the identity of anomalous sources. This research focuses on the use of neuromorphic algorithms for the purpose of developing low power, accurate radionuclide identification devices that can filter out non-anomalous background radiation and other artifacts created by gamma-ray detector measurement equipment, along with identifying clandestine, radioactive material.
A sparse …
Investigation Of Environmental-Friendly, Membraneless Hydrogen Peroxide Fuel Cells, Bao Nguyen
Investigation Of Environmental-Friendly, Membraneless Hydrogen Peroxide Fuel Cells, Bao Nguyen
Dissertations and Theses
Human-induced climate change is one of the biggest threats to humanity in the 21st century. This is caused by the increase in greenhouse gas concentrations in the Earth's atmosphere. The burning of fossil fuels is the primary cause of climate change. This problem can be addressed by replacing fossil fuels with fuel sources that have clean by-products and are cost-effective. For the last few decades, hydrogen (H2) has been extensively studied as an alternative to carbon-based fossil fuels. Currently, H2 still has many shortcomings for commercial applications. The photocatalytic production of H2 still suffers from …
Proximal Policy Optimization For Radiation Source Search, Philippe Erol Proctor
Proximal Policy Optimization For Radiation Source Search, Philippe Erol Proctor
Dissertations and Theses
Rapid localization and search for lost nuclear sources in a given area of interest is an important task for the safety of society and the reduction of human harm. Detection, localization and identification are based upon the measured gamma radiation spectrum from a radiation detector. The nonlinear relationship of electromagnetic wave propagation paired with the probabilistic nature of gamma ray emission and background radiation from the environment leads to ambiguity in the estimation of a source's location. In the case of a single mobile detector, there are numerous challenges to overcome such as weak source activity, multiple sources, or the …
Simulation Of Light Propagation Captured By Photoemission Electron Microscopy (Peem), Nabila Islam
Simulation Of Light Propagation Captured By Photoemission Electron Microscopy (Peem), Nabila Islam
Dissertations and Theses
The Photoemission electron microscopes (PEEM) is a powerful tool capable of synchronously imaging wave nature of light manifested by interference patterns as well as its particle nature through the energy exchange between the incident photons and the photoemitted imaging electrons. PEEM offers a non-invasive high-resolution approach for studying light propagation and interaction phenomena within a nanophotonic waveguide [7,8]. The electric field intensity variation of the interference pattern yielded by the interaction between the incident light and the guided mode coupled into the waveguide produces varying photoemission yields creating contrast in PEEM image. The guided modes cannot be excited simply by …
Self-Contained Photon Coincidence Counting With Ni Myrio Ecosystem, Georges Oates Larsen, Andres H. La Rosa
Self-Contained Photon Coincidence Counting With Ni Myrio Ecosystem, Georges Oates Larsen, Andres H. La Rosa
University Honors Theses
Digital coincidence counting units (CCU) have made experimental verification of fundamental quantum mechanical principles financially accessible to undergraduate level teaching programs. However, recent implementations of these systems are not easily ported to National Instruments (NI) FPGAs, making them unsuitable for physics departments that have heavily invested in the NI ecosystem. Therefore, there is clear need for a detailed implementation based on an NI FPGA. We present a formal description of one such implementation, based on the NI myRIO (NI's lower-cost, student-oriented offering) which achieves 6.9 ns minimum guaranteed-distinguishable delay and 32.2 MHz peak coincidence counting rate with four input channels …
Photoemission Electron Microscopy For Direct Observation Of Photonic And Plasmonic Phenomena, Theodore Stenmark
Photoemission Electron Microscopy For Direct Observation Of Photonic And Plasmonic Phenomena, Theodore Stenmark
Dissertations and Theses
Photoemission electron microscopy (PEEM) is a high-resolution microscopy technique that collects photoemitted electrons from the sample surface to form an image. PEEM offers a non-scanning imaging method with a spatial resolution in the range of 5-100nm by combining the advantages of light excitation and electron imaging. Our work looks at PEEM as an analysis tool for photonic and plasmonic phenomena. Photonic wave guiding structures exhibiting a strong dispersion relation have attracted considerable attention for applications in integrated optics, communications and sensing devices. Line defects in a photonic crystal (PC) slab offer a highly efficient way to create light with group …
Quantifying Biotic Voc Emissions From Moss: Air Quality Impacts Of Isoprene And Monoterpenes In Urban Environments, Danlyn L. Brennan
Quantifying Biotic Voc Emissions From Moss: Air Quality Impacts Of Isoprene And Monoterpenes In Urban Environments, Danlyn L. Brennan
University Honors Theses
Plant-derived biogenic volatile organic compound (VOC) emissions contribute to secondary emissions of molecules such as ground-level ozone (O3) and PM 2.5 which are known to be harmful to the environment and negatively impact human health. Currently, the most known biogenic VOC emissions are from vascular plants like trees and economically significant crops. Air quality models use known emission rates from these measurements and have many unknown sources yet to identify. Unknown values of emissions occur due to a lack of measurements of a wider variety of plants, especially that of smaller and lesser-studied species of bryophytes; mosses. This …
Complex Fluid Dynamics: Chemo-Hydrodynamics Driven By Autocatalytic Reaction Fronts, Matthew Walter Eskew
Complex Fluid Dynamics: Chemo-Hydrodynamics Driven By Autocatalytic Reaction Fronts, Matthew Walter Eskew
Dissertations and Theses
Chemo-hydrodynamics generated from reaction-diffusion-convection processes of autocatalytic chemical systems are extensively studied for their applications in modeling complex systems. Compared to the more extensively studied autocatalytic systems, chlorite-tetrathionate and chlorite-trithionate, the chlorite-thiourea systems is relatively unexplored. Compared to the two previous systems, chlorite-thiourea has more straightforward chemical kinetics. To narrow the gap between chlorite-thiourea and the other systems a combination of experimental study and numerical simulation were employed to quantify this system.
Compared to established literature, experiments were performed at five orders of magnitude lower concentration of indicator, minimizing confounding effects of indicator on hydrodynamic motion. To accurately image the …
Investigation Of Prussian Blue Analogues As Cathode Materials For Next Generation Batteries, Neal Walters Kuperman
Investigation Of Prussian Blue Analogues As Cathode Materials For Next Generation Batteries, Neal Walters Kuperman
Dissertations and Theses
Since the beginning of the industrial revolution, the average global temperature has risen about 1 °C due increases in anthropogenic greenhouse gases emitted into the atmosphere. Of all human produced greenhouse gases, carbon dioxide is the most prevalent, with the production of electricity from fossil fuels being the major contributor.
Solar and wind power are promising net zero emission energy sources but only accounted for ~5% of global electricity generation in 2016. The most significant hurdle hindering their widespread adoption is the intermittent nature of the electricity generation. To overcome this limitation, significant resources need to be put into the …
Investigation Of Magnetism In Transition Metal Chalcogenide Thin Films, Michael Adventure Hopkins
Investigation Of Magnetism In Transition Metal Chalcogenide Thin Films, Michael Adventure Hopkins
Dissertations and Theses
Layered two dimensional films have been a topic of interest in the materials science community driven by the intriguing properties demonstrated in graphene. Tunable layer dependent electrical and magnetic properties have been shown in these materials and the ability to grow in the hexagonal phase provides opportunities to grow isostructural stacked heterostructures. In this investigation, cobalt selenide (CoSe) and nickel selenide (NiSe) were grown in the hexagonal phase, which consist of central metal atoms that are natively ferromagnetic in bulk, hence providing the potential for interesting magnetic phases in thin film arrangements as well. These structures may play a role …
Numerical Model Of A Radio Frequency Ion Source For Fusion Plasma Using Particle-In-Cell And Finite Difference Time Domain, Augustin L. Griswold
Numerical Model Of A Radio Frequency Ion Source For Fusion Plasma Using Particle-In-Cell And Finite Difference Time Domain, Augustin L. Griswold
University Honors Theses
Radio frequency (RF) plasma sources are common tool for application and study, and of particular interest for inertial electrostatic (IEC) fusion. Computational analysis is often carried out using particle in cell (PIC) methods or finite difference time domain (FDTD). However, a more holistic analysis is necessary as the particle distribution is highly dependant on the fields created by the plasma source. Herein, an analysis of a particular planar RF electrode with deuterium gas is provided which covers the fields and the particle behaviour using first FDTD then PIC. Further applications are discussed as well as further directions for this study.
Measurements Of N₂O And Sf₆ Mole Fraction And N₂O Isotopic Composition Between 1978 And 1997 In Archived Air Samples From Cape Meares, Oregon, Terry Clinton Rolfe
Measurements Of N₂O And Sf₆ Mole Fraction And N₂O Isotopic Composition Between 1978 And 1997 In Archived Air Samples From Cape Meares, Oregon, Terry Clinton Rolfe
Dissertations and Theses
Nitrous oxide (N2O) is the third most important greenhouse gas (GHG) behind carbon dioxide (CO2) and methane (CH4). Sulfur hexafluoride (SF6) does not add significantly to climate forcing by itself due to the low concentration in the atmosphere; however, it is one of the most powerful GHG known. Measurements of atmospheric N2O made prior to mid-1990 have larger uncertainties than later periods due to advancements made in gas chromatography (GC) methods. Few atmospheric SF6 measurements pre-1990 exist, especially in the northern hemisphere. Archived samples may be analyzed using updated …
Sensors And Portable Instruments For Postharvest Agriculture, Ryan M. Lerud
Sensors And Portable Instruments For Postharvest Agriculture, Ryan M. Lerud
Dissertations and Theses
The sensing needs for the fresh produce industry can be split into two primary stages: during maturation in the field, also referred to as Precision Farming, and during storage and transport of the produce, or Postharvest Storage. This work seeks to improve the accuracy and reliability of commercially available electrochemical and spectroscopic sensors tailored to the sensing needs of the fresh produce industry. For electrochemical sensing, this study proposes the use of an inline filter to remove polar organic compounds, which can interfere with the readings of a platinum-based electrochemical sensor. A 50% improvement in measurement accuracy was achieved when …
Capillary Migration Of Large Confined Drops In Non-Wetting Wedges, Logan John Torres
Capillary Migration Of Large Confined Drops In Non-Wetting Wedges, Logan John Torres
Dissertations and Theses
When confined within containers or conduits, drops and bubbles migrate to regions of minimum energy by the combined effects of surface tension, surface wetting, system geometry, and initial conditions. Such capillary phenomena are exploited for passive phase separation operations in micro-fluidic devices on earth and macro-fluidic devices aboard spacecraft. Our study focuses on the migration and ejection of large inertial-capillary drops confined between tilted planar hydrophobic substrates. In our experiments, the brief nearly weightless environment of a drop tower allows for the study of such capillary dominated behavior for up to 10 mL water drops with migration velocities up to …
Localized Photoemission In Triangular Gold Antennas, Christopher M. Scheffler
Localized Photoemission In Triangular Gold Antennas, Christopher M. Scheffler
Dissertations and Theses
With the development of ultra-fast laser technology, several new imaging techniques have pushed optical resolution past the diffraction limit for traditional light-based optics. Advancements in lithography have enabled the straightforward creation of micron- and nanometer-sized optical devices. Exposing metal-dielectric structures to light can result in surface plasmon excitation and propagation along the transition interface, creating a surface plasmon polariton (SPP) response. Varying the materials or geometry of the structures, the plasmonic response can be tailored for a wide range of applications.
Photoemission electron microscopy (PEEM) has been used to image excitations in micron-sized plasmonic devices. With PEEM, optical responses can …