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Childhood And Adulthood Passive And Active Smoking, And The Abo Group As Risk Factors For Pancreatic Cancer In Women, Anne-Laure Vedie, Nasser Laouali, Amandine Gelot, Gianluca Severi, Marie-Christine Boutron-Ruault, Vinciane Rebours Jan 2023

Childhood And Adulthood Passive And Active Smoking, And The Abo Group As Risk Factors For Pancreatic Cancer In Women, Anne-Laure Vedie, Nasser Laouali, Amandine Gelot, Gianluca Severi, Marie-Christine Boutron-Ruault, Vinciane Rebours

Biostatistics and Epidemiology Faculty Publications Series

Objectives

Active smoking and the A blood group are associated with pancreatic adenocarcinoma (PC) risk. However, potential interactions between those risk factors and the role of passive smoking have been little investigated. We aimed to explore specific and joint associations of passive and active smoking, and effect modification by the ABO blood group in French women.

Methods

The study included 96,594 women from the E3N prospective cohort, mean age: 49 years (SD 6.7). Information on active and passive smoking was reported at inclusion and throughout follow-up. Cases were classified according to the International Classification of Diseases 10. Associations with passive …


The Therapeutic Potential Of Natural Products From Vaccinium Berries For Viral And Lung Diseases Through An Improved Lc-Ms-Based Chemometric Approach, Vanya I. Petrova Feb 2018

The Therapeutic Potential Of Natural Products From Vaccinium Berries For Viral And Lung Diseases Through An Improved Lc-Ms-Based Chemometric Approach, Vanya I. Petrova

Dissertations, Theses, and Capstone Projects

Smoking is a global epidemic that creates serious health and economic burden. It is the primary, preventative factor for the majority of causes of death worldwide. Analysis of publicly available data revealed that smoking prevalence rates among the youth in developing countries, especially in Bulgaria, are alarmingly high. The Bulgarian population has one of the highest percentages of smokers and the second highest rate among teenage girls. Consequently, chronic diseases affected by smoking, such as chronic obstructive pulmonary disorder (COPD), have been increasing there in the last five years. Poland, on the other hand, is an exemplary outlier for the …


The Effect Of Poplar Psngs1.2 Overexpression On Growth, Secondary Cell Wall, And Fiber Characteristics In Tobacco, Tingting Lu, Lulu Liu, Minjing Wei, Yingying Liu, Zianshang Qu, Chuanping Yang, Hairong Wei, Zhigang Wei Jan 2018

The Effect Of Poplar Psngs1.2 Overexpression On Growth, Secondary Cell Wall, And Fiber Characteristics In Tobacco, Tingting Lu, Lulu Liu, Minjing Wei, Yingying Liu, Zianshang Qu, Chuanping Yang, Hairong Wei, Zhigang Wei

Michigan Tech Publications

The glutamine synthetase (GS1) is a key enzyme that catalyzes the reaction of glutamate and ammonia to produce glutamine in the nitrogen (N) metabolism. Previous studies on GS1s in several plant species suggest that overexpression of GS1s can enhance N utilization, accelerate plant vegetative growth, and change wood formation. In this study, we isolated a GS1 gene, termed PsnGS1.2, from Populus simonii × Populus nigra. This gene was expressed at a higher level in roots, and relatively lower but detectable levels in xylem, leaves and phloem of P. simonii × P. nigra. The protein encoded by PsnGS1.2 is …


Nicotine Video Questions, Sheryl Hemkin Jan 2018

Nicotine Video Questions, Sheryl Hemkin

5. Nicotine

No abstract provided.


Lesson Plan: It’S Not Just The Smoke - The Effects Of Nicotine On The Body, Sheryl Hemkin Jan 2018

Lesson Plan: It’S Not Just The Smoke - The Effects Of Nicotine On The Body, Sheryl Hemkin

5. Nicotine

No abstract provided.


Inter-Relationships Linking Probability Of Becoming A Case Of Nicotine Dependence With Frequency Of Tobacco Cigarette Smoking, Olga A. Vsevolozhskaya, James C. Anthony Dec 2016

Inter-Relationships Linking Probability Of Becoming A Case Of Nicotine Dependence With Frequency Of Tobacco Cigarette Smoking, Olga A. Vsevolozhskaya, James C. Anthony

Biostatistics Faculty Publications

INTRODUCTION: Once smoking starts, some tobacco cigarette smokers (TCS) can make very rapid transitions into tobacco dependence syndromes (TCD). With adjustment for smoking frequency, we posit female excess risk for this rapid-onset TCD. In a novel application of functional analysis for tobacco research, we estimate four Hill function parameters and plot TCD risk against a gradient of smoking frequency, as observed quite soon after smoking onset.

METHODS: In aggregate, the National Surveys of Drug Use and Health, 2004-2013, identified 1546 newly incident TCS in cross-sectional research, each with standardized TCD assessment.

RESULTS: Hill function estimates contradict our apparently over-simplistic hypothesis. …


Thermal Decomposition Of Electronic Cigarette Liquids, Robert Paul Jensen Aug 2016

Thermal Decomposition Of Electronic Cigarette Liquids, Robert Paul Jensen

Dissertations and Theses

Electronic cigarette liquid (e-liquid) is a solution of propylene glycol and/or glycerol with varying concentrations of nicotine and flavorants. Inhalation of vaporized e-liquid is a method of nicotine delivery that is growing in popularity and is commonly regarded as safe relative to smoking traditional tobacco products. The thermal decomposition of glycerol and propylene glycol is typical of alcohols and has been investigated, although not exhaustively. In this work, samples of propylene glycol and glycerol were vaporized using an electronic cigarette (e-cigarette) and were analyzed for evidence of decomposition using nuclear magnetic resonance (NMR) spectroscopy. E-cigarettes are shown to degrade glycerol …


Soil Management And Nitrogen Dynamics In Burley Tobacco Rotations, Congming Zou Jan 2015

Soil Management And Nitrogen Dynamics In Burley Tobacco Rotations, Congming Zou

Theses and Dissertations--Plant and Soil Sciences

Agronomic practices, including tillage, crop rotation and N fertilization, have been developed to efficiently manage soil N dynamics and crop N nutrition. These practices can affect soil organic carbon (SOC) and soil total nitrogen (STN) sequestration, and consequently influence soil nitrogen mineralization (SNM) and crop N nutrition. However, little research has been systematically and simultaneously conducted to examine the effect of agronomic management on (1) SOC and STN stocks; (2) SNM; and (3) crop N nutrition. Burley tobacco (Nicotiana tobacum L.) is a N demanding crop and subject to inefficiency in N fertilization. Moreover, conservation tillage and rotation have been …


Limitations And Benefits To Cultivating Tobacco, Edwin L. Ritchey, Gary K. Palmer Jan 2014

Limitations And Benefits To Cultivating Tobacco, Edwin L. Ritchey, Gary K. Palmer

Plant and Soil Sciences Research Report

Historically, between-row cultivation for weed control has been an integral part of tobacco production. In one season, a grower might perform five or more cultivations and several hand weeding operations for adequate weed control. Early herbicide chemistries would control some weeds, but not all, forcing the producer to cultivate and hand weed. The development of better herbicides improved the range of weeds controlled, sometimes to the point that cultivation for weed control was not warranted. Many producers are so accustomed to cultivating they have forgotten why cultivation was necessary. The decision to cultivate should largely be based on the presence …


Meta-Analysis Of Studies Investigation Of The Effect Of Smoking Cessation On Impatience, Miriam Claire Dash Jan 2014

Meta-Analysis Of Studies Investigation Of The Effect Of Smoking Cessation On Impatience, Miriam Claire Dash

Graduate College Dissertations and Theses

(DSM-IV-TR/) nor in withdrawal scales. However, a related term, "impatience" is listed in some nicotine withdrawal scales. (Hughes J. R., Measurements of the Effects of Abstinence from Tobacco: A Qualitative Review, 2007). Although impatience is not a synonym of impulsivity, both share the synonym "impetuous". Therefore, impatience can be considered a measure of impulsivity. Although some reviews of the effect of smoking cessation on impatience have occurred, we know of no quantitative review of prospective studies of whether smoking cessation increases impatience.

Purpose: To evaluate the effect of smoking cessation on impatience as measured by the Minnesota Nicotine Withdrawal Scale-Revised …


The Biophysical Effects Of Deuterium Oxide On Biomolecules And Living Cells Through Open Notebook Science., Anthony Salvagno Sep 2013

The Biophysical Effects Of Deuterium Oxide On Biomolecules And Living Cells Through Open Notebook Science., Anthony Salvagno

Physics & Astronomy ETDs

This dissertation explores various effects of deuterium oxide (D2O also known as heavy water) in nature. Water is everywhere and interacts with just about everything. As such, it would be quite a daunting task to characterize every effect that water exhibits on everything in the universe. This research is a small piece of the puzzle, and provides some fundamental understanding of how water interacts with other molecules. This is done from two viewpoints: (1) the effects of heavy water on living cells and (2) the effects of heavy water on molecules. Varying concentrations of deuterium oxide were used as the …


Repeated Changes In Reported Sexual Orientation Identity Linked To Substance Use Behaviors In Youth, Miles Q. Ott, David Wypij, Heather L. Corliss, Margaret Rosario, Sari L. Reisner, Allegra R. Gordon, S. Bryn Austin Apr 2013

Repeated Changes In Reported Sexual Orientation Identity Linked To Substance Use Behaviors In Youth, Miles Q. Ott, David Wypij, Heather L. Corliss, Margaret Rosario, Sari L. Reisner, Allegra R. Gordon, S. Bryn Austin

Statistical and Data Sciences: Faculty Publications

Purpose—Previous studies have found that sexual minority (e.g., lesbian, gay, bisexual) adolescents are at higher risk of substance use than heterosexuals, but few have examined how changes in sexual orientation over time may relate to substance use. We examined the associations between change in sexual orientation identity and marijuana use, tobacco use, and binge drinking in U.S. youth.

Methods—Prospective data from 10,515 U.S. youth ages 12-27 years in a longitudinal cohort study were analyzed using sexual orientation identity mobility measure M (frequency of change from 0 [no change] to 1 [change at every wave]) in up to five waves of …


Molecular Products From The Thermal Degradation Of Selected Tobacco Components: Lignin, Tyrosine, Glutamic Acid, And Modeling Of Lignin Pyrolysis Using Chemkin Combustion Suite, Joshua Kiprotich Kibet Jan 2013

Molecular Products From The Thermal Degradation Of Selected Tobacco Components: Lignin, Tyrosine, Glutamic Acid, And Modeling Of Lignin Pyrolysis Using Chemkin Combustion Suite, Joshua Kiprotich Kibet

LSU Doctoral Dissertations

This study explores the thermal decomposition behavior of selected tobacco components: lignin, tyrosine, and glutamic acid using the system for thermal diagnostic studies (STDS) in an in-line gas chromatography-mass spectrometer analytical technique. The pyrolysis conditions employed in this study were a flowing atmosphere of nitrogen and 4% O2 in nitrogen at a residence time of 0.2 seconds for a total pyrolysis time of 3 minutes. The results identified common relationships between the two modes of reaction atmospheres, as well as some differences. While some products were favored by an inert regime, some were favored under an oxidative regime. Oxidative pyrolysis …


Effect Of Tray Type And Tray Covering On Wicking Speed, Germination, And Spiral Rooting Of Tobacco, William A. Bailey, Bill Pitt Jan 2012

Effect Of Tray Type And Tray Covering On Wicking Speed, Germination, And Spiral Rooting Of Tobacco, William A. Bailey, Bill Pitt

Plant and Soil Sciences Research Report

Poor tray wicking and spiral rooting continue to be recurring concerns in tobacco float systems. Poor wicking of trays can usually be attributed to old media or media that was improperly stored for extended periods of time. Tray design may also influence speed of wicking. The clay-based pelleting materials used to coat tobacco seeds are thought to cause damage to the emerging root radical under certain conditions, leading to an increased incidence of spiral root. Practices that change the microenvironment at the top of the cell area surrounding the seed may reduce spiral rooting by altering the breakdown of the …


Tillage And Subsoiling Effects On Soil Compaction And Yield Of Burley Tobacco, Edwin L. Ritchey, Robert C. Pearce, John H. Grove Jan 2012

Tillage And Subsoiling Effects On Soil Compaction And Yield Of Burley Tobacco, Edwin L. Ritchey, Robert C. Pearce, John H. Grove

Plant and Soil Sciences Research Report

Historically, tobacco producers have relied heavily on surface tillage to prepare fields for transplanting. This typically involved moldboard plowing, followed by several secondary tillage operations, such as discing then leveling with a soil finisher. Transplanter developments and modifications in the late 1990’s, coupled with new chemicals for weed control, made no-till (NT) tobacco a viable option for tobacco producers in Kentucky (KY).


Environmental Analysis Of Toxic Metals Produced By Cigarette Smoking, Catherine H. Swandby, Melissa C. Rhoten, Joseph E. Garcia Apr 2010

Environmental Analysis Of Toxic Metals Produced By Cigarette Smoking, Catherine H. Swandby, Melissa C. Rhoten, Joseph E. Garcia

Theses & Honors Papers

Trace metal elements introduced into our environment from anthropogenic sources can become toxic at high levels contributing to a host of human and animal health problems. The purpose of this work is to initially characterize toxic metals present in cigarette tobacco and ash using Electrothermal Atomic Absorption Spectroscopy (ETAAS). The broader impact of this study is to assess the environmental effects of cigarette smoking around designated smoking areas on the Longwood University campus. Smokers may not be informed about the potential harm to the environment from "ashing" directly on the ground. If the toxic metals present in cigarette ash are …


Radon In Caves: Clinical Aspects, Stephen A. Craven, Berend J. Smit Jan 2006

Radon In Caves: Clinical Aspects, Stephen A. Craven, Berend J. Smit

International Journal of Speleology

Historical, experimental and clinical evidence is presented to suggest that radon constitutes a relatively small carcinogenic risk for casual visitors to caves. The risk is dependent on radon levels and the smoking of tobacco. Show cave guides, chronically exposed to radon, may be at increased risk for lung cancer due to the effects of radon, especially if they are smokers of tobacco.


The Effect Of Rate And Source Of Potassium Fertilizer On Cured Leaf Yield Of Burley Tobacco And Leaf Content And Soil Test Levels Of Potassium And Magnesium, Kenneth L. Wells, James E. Dollarhide, Mark Reese Jan 1995

The Effect Of Rate And Source Of Potassium Fertilizer On Cured Leaf Yield Of Burley Tobacco And Leaf Content And Soil Test Levels Of Potassium And Magnesium, Kenneth L. Wells, James E. Dollarhide, Mark Reese

Soil Science News and Views

In response to questions being asked by tobacco growers about the effectiveness of sulfate of potash magnesia (SPM; 21% K2O and 11% Mg) as coinpared to sulfate of potash (SP; 50% K2O), field studies were conducted during 1993-1994 to compare the two potassium (K) sources for use on burley tobacco. Any effect of SPM on yield of tobacco should be due to Mg since the only difference between the two sources in kind of nutrient contained is the presence of magnesium (Mg) in SPM. To compare the two K sources, we selected field sites low enough …


Effect Of Subsoiling On Yield Of Burley Tobacco, Kenneth L. Wells, Kim D. Strohmeier Jan 1995

Effect Of Subsoiling On Yield Of Burley Tobacco, Kenneth L. Wells, Kim D. Strohmeier

Soil Science News and Views

Compaction of tobacco fields caused by overworking or working soils when they are too wet has become a topic of concern to burley producers in recent years. Despite the viewpoint of some producers that annual subsoiling of tobacco fields is a profitable practice, particularly on soils which percolate water slowly, the University of Kentucky College of Agriculture recommends subsoiling only for a defined compaction problem. In such cases, some field studies have shown increased yields of burley to tillage practices that penetrate and shatter the compacted layer. Questions persist, however, about the effectiveness of single shank subsoilers used annually by …


Estimated Nutrient Content And Uptake By Kentucky's Crops, Kenneth L. Wells, William O. Thom Jan 1994

Estimated Nutrient Content And Uptake By Kentucky's Crops, Kenneth L. Wells, William O. Thom

Soil Science News and Views

A commonly asked question by crop producers is, "how many pounds of plant nutrients do my crops take up?" While the absolute answer to this varies by yield and soil fertility, useful estimates can be made from research data to enable a producer to have a "ballpark" value for nutrient up-take by some of the major crops of Kentucky. The following tables contain estimates of nitrogen (N), phosphorus (P),and potassium (K) contained in certain crops and the amount of N, phosphate (P2O5), and potash (K,O) taken up by tobacco, corn, soybeans, wheat, alfalfa hay, clover grass …


Factors Affecting Color Of Cured Burley Leaf, J. L. Sims, Gary K. Palmer, Kenneth L. Wells Jan 1993

Factors Affecting Color Of Cured Burley Leaf, J. L. Sims, Gary K. Palmer, Kenneth L. Wells

Soil Science News and Views

Much interest has been shown by tobacco growers during recent months in fertilization and or other management practices that can be used to produce darker and redder cured leaf of burley tobacco. The purpose of this newsletter is to summarize what we know about some of the factors which affect color of cured leaf.


Fall Fertilization And Liming For Tobacco Production, J. L. Sims, Kenneth L. Wells Jan 1991

Fall Fertilization And Liming For Tobacco Production, J. L. Sims, Kenneth L. Wells

Soil Science News and Views

Proper nutrition of tobacco is a prerequisite for achieving high yields of cured leaf possessing desirable marketing characteristics. Together with the variety grown, soils, climate, and curing conditions, a desirable nutrient environment greatly influences yield, quality, and usability of the leaf produced. Late summer and early fall is a good time to select fields for future tobacco crops or to sample this year's tobacco fields which will be used for tobacco next year, and to assess their needs for lime, phosphorus, and potassium. Planning fertilization strategies this fall that lead to increased profit is much more effective than waiting until …


The Effect Of Fall And Spring Tillage Of A Compacted Soil On Corn And Tobacco Yields, Kenneth L. Wells, Roy V. Catlett Jan 1990

The Effect Of Fall And Spring Tillage Of A Compacted Soil On Corn And Tobacco Yields, Kenneth L. Wells, Roy V. Catlett

Soil Science News and Views

Soil compaction is being diagnosed in increasing instances as the cause of poor crop performance in Kentucky. While the basic causes of compaction can usually be identified, it is much more difficult to prescribe techniques to solve the problem. Following identification of compacted soil as being the cause of poor corn growth in a field in Shelby County, Kentucky, a study was conducted to compare three tillage tools on production of corn and tobacco. The compacted zone was within the top 6-inch layer of soil.


Production Of No-Tillage Burley Tobacco, Jack M. Zeleznik, R. E. Phillips Jan 1990

Production Of No-Tillage Burley Tobacco, Jack M. Zeleznik, R. E. Phillips

Soil Science News and Views

In the early 1970's, researchers at the University of Kentucky produced burley tobacco by using no-tillage methods. These studies were abandoned a few years later due to poor growth, poor plant survival, and the lack of adequate weed control as the contributing factors. In 1984, the experimental production of no-tillage burley tobacco was reinitiated with the hopes that the newer herbicides would perform more effectively for no-tillage tobacco production. Burley producers could realize several potential advantages to no-tillage tobacco production if the yields produced by no-tillage were equal to or near those of conventional tillage. These potential advantages would include: …


Will Liming Acid Soils Now Be Adequate For Spring Needs?, Kenneth L. Wells, J. L. Sims Jan 1989

Will Liming Acid Soils Now Be Adequate For Spring Needs?, Kenneth L. Wells, J. L. Sims

Soil Science News and Views

Each spring many farmers are faced with seeding forages, corn, and soybeans, and transplanting tobacco into acid soils. The choices are either to go ahead with planting and do nothing, don't plant, or to try some liming practice and hope that it works. The results from planting without doing anything may be disastrous or result in limited crop performance. While not planting is a viable option for some producers, most cannot afford this choice. The question most often faced is, "Will liming now do any good for this year's crop?"


Foliar Fertilization Of Burley Tobacco At Topping, Kenneth L. Wells, Kim D. Strohmeier Jan 1989

Foliar Fertilization Of Burley Tobacco At Topping, Kenneth L. Wells, Kim D. Strohmeier

Soil Science News and Views

Many burley growers follow the practice of applying 1-2 gallons/A of liquid fertilizer to their tobacco crop by mixing it with their sucker control chemical and spraying the combined mixture on the crop soon after topping. This practice is thought to improve yields. However, previously reported testing of this practice by the University of Kentucky College of Agriculture indicated that it did not improve yields.


Control Measures For Manganese Toxicity Of Burley At Transplating Time, Kenneth L. Wells, J. L. Sims May 1987

Control Measures For Manganese Toxicity Of Burley At Transplating Time, Kenneth L. Wells, J. L. Sims

Soil Science News and Views

Manganese (Mn) toxicity of burley tobacco is viewed by tobacco specialists in Kentucky as the greatest single factor which reduces yields. Estimates are that this problem adds 30 to 50 million dollars to the cost of burley production because of the greater acreage (and all associated costs) required by growers to produce their allotment. And, even though the cause and cure of Mn toxicity has been known for about 50 years, many growers are caught each year at transplanting time with no knowledge as to whether Mn toxicity may be a problem in their fields. The solution to Mn toxicity …


Efficient Use Of Fertilizer On Tobacco, J. L. Sims Apr 1985

Efficient Use Of Fertilizer On Tobacco, J. L. Sims

Soil Science News and Views

Recent increases in fertilizer prices and other productions costs have stimulated interest in ways to increase the efficiency of fertilizer use while maintaining or increasing yields and quality of tobacco. Growers currently spend about $250 per acre for fertilizer. Although this represents only 15 to 20 percent of the total cash costs per acre, it is one category of cash expenses that can be decreased.


Developing A Fertilizer Program For Tobacco, J. L. Sims Aug 1984

Developing A Fertilizer Program For Tobacco, J. L. Sims

Soil Science News and Views

Use of adequate amounts of required fertilizer nutrients are necessary to increase both yield and quality of tobacco if they are lacking in a soil. However, to insure maximum profits from the tobacco crop, careful consideration must be given to fertilizer management (kinds, rates, and methods and times of fertilizer application), the chemical and physical characteristics of the soil, and the crops grown in rotation with tobacco. To develop a profitable fertilization program for tobacco requires thoughtful planning on the part of the grower. Late summer and early fall is a good time to make these plans for the future.


Current Research On Band Application Of Fertilizer To Burley Tobacco, J. L. Sims Apr 1983

Current Research On Band Application Of Fertilizer To Burley Tobacco, J. L. Sims

Soil Science News and Views

Present Status: Generally, past research conducted in the United States has shown that only one-half to two-thirds as much fertilizer is required to produce maximum crop yields when the fertilizer is properly banded as when it is broadcast. However, the magnitude of plant response to banding compared to broadcast applications varies widely with soil nutrient levels, soil temperature, soil pH, and the mobility of the nutrient being applied. Greatest benefits from banding result from (a) applications to soils having low or very-low soil test levels of the nutrient in question, (b) applications to crops grown in cool climates, (3) applications …