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Diffusion Of A Rodlike Virus In Complex Solutions, Randall Charles Cush Jan 2003

Diffusion Of A Rodlike Virus In Complex Solutions, Randall Charles Cush

LSU Doctoral Dissertations

Entanglement phenomena in concentrated polymer solutions remain an interesting and challenging problem. It is still unclear how entanglement onset affects polymer chain motion at small distance scales. One way to study such motion is to follow the diffusion of a probe particle while increasing the concentration of the polymer. Many such studies have been done using probes ranging from linear and star polymers to various colloidal particles; however, relatively few studies have used rodlike probes. Rodlike probes are potentially more interesting due to the added information that may be gained by following rotational as well as translational diffusion. The anisotropic …


Constraint Preserving Boundary Conditions For The Linearized Einstein Equations, Gioel Calabrese Jan 2003

Constraint Preserving Boundary Conditions For The Linearized Einstein Equations, Gioel Calabrese

LSU Doctoral Dissertations

The successful construction of long time convergent finite difference schemes approximating highly gravitating systems in general relativity remains an elusive task. The presence of constraints and the introduction of artificial time-like boundaries contribute significantly to the difficulty of this problem. Whereas in the absence of boundaries the Bianchi identities ensure that the constraints vanish during evolution provided that they are satisfied initially, this is no longer true when time-like boundaries are introduced. In this work we consider the linearization around the Minkowski space-time in Cartesian coordinates of the generalized Einstein-Christoffel system and analyze different kinds of boundary conditions that are …


Genome Analysis: Mutation Analysis Using Near Infrared Laser-Induced Fluorescence (Nir-Lif) And Single Molecule Detection In Microfluidic Devices, Musundi Ben Wabuyele Jan 2003

Genome Analysis: Mutation Analysis Using Near Infrared Laser-Induced Fluorescence (Nir-Lif) And Single Molecule Detection In Microfluidic Devices, Musundi Ben Wabuyele

LSU Doctoral Dissertations

A number of genotyping methods have been developed for mutation analysis, each of which has its own unique advantage. DNA amplification via polymerase chain reaction (PCR) provides an unlimited supply of material for subsequent genetic analysis even in case where only a single copy of the DNA molecule is present in the sample. Research presented in this dissertation first examines the efficiency of in vitro amplification of single copy DNA with subsequent sequencing analysis of PCR product. The PCR products (amplicons) were investigated for possible alteration, distortions or mutations due to the amplification process. The sequencing data for single copy …


Synchrotron Radiation As A Probe Of Chemical Information Using Novel Experimental Configurations, George Farquar Jan 2003

Synchrotron Radiation As A Probe Of Chemical Information Using Novel Experimental Configurations, George Farquar

LSU Doctoral Dissertations

Determination of chemical information with synchrotron radiation is an area of great scientific interest, and expanding the range of available techniques is the topic of this dissertation. The experimental methods described herein allows for a significant advancement of the availability of subtle chemical information. This dissertation uses ionizing radiation to study three chemical systems. First, the l=3 shape resonance in CO is investigated using a cryogenically cooled gas jet. Shape resonant effects have been studied for many years. Previously, this was accomplished on the vibrational structure of molecules with a limited ability to determine the rotational substructure effects. A dramatic …


The Effect On Water Quality Of Riverine Input Into Coastal Wetlands, Robert Raymond Lane Jan 2003

The Effect On Water Quality Of Riverine Input Into Coastal Wetlands, Robert Raymond Lane

LSU Doctoral Dissertations

This dissertation focuses on impact on water quality of two freshwater diversions, the Bonnet Carre Spillway and the Caernarvon freshwater diversion, as well as the Atchafalaya River Estuarine Complex. As water passed through the Bonnet Carre Spillway, there were reductions in total suspended sediment concentrations of 82-83%, in nitrite+nitrate of 28-42%, in total nitrogen (TN) of 26-30%, and in total phosphorus (TP) of 50-59%. The Si:N ratio generally increased and the N:P ratio decreased from the river to the plume edge in Lake Pontchartrain. At the Caernarvon diversion, there were reductions in concentrations of dissolved inorganic Si, N, and P …


Analyzing The Impact Of Changing Software Requirements: A Traceability-Based Methodology, James Steven O'Neal Jan 2003

Analyzing The Impact Of Changing Software Requirements: A Traceability-Based Methodology, James Steven O'Neal

LSU Doctoral Dissertations

Software undergoes change at all stages of the software development process. Changing requirements represent risks to the success and completion of a project. It is critical for project management to determine the impact of requirement changes in order to control the change process. We present a requirements traceability based impact analysis methodology to predictively evaluate requirement changes for software development projects. Trace-based Impact Analysis Methodology (TIAM) is a methodology utilizing the trace information, along with attributes of the work products and traces, to define a requirement change impact metric for determining the severity of a requirement change. We define the …


Level Of Essentialness Of A Node In Flowcharts And Its Application To Program Testing, Osman Kandara Jan 2003

Level Of Essentialness Of A Node In Flowcharts And Its Application To Program Testing, Osman Kandara

LSU Doctoral Dissertations

Program testing is important to develop bug free software. A common form of program testing involves selecting test cases which execute (cover) a given set W of statements in the program. In regression testing, W typically forms a small subset of the program. It is often possible to find an alternate small set W so that execution of W' implies execution of W. We develop concepts and algorithms for finding W' as small as possible with the condition that the statements in W' are "close" to those in W in terms of program structure. These concepts generalize the notion of …


Atomic And Electronic Structure Of Bulk Intermetallic And Heteroepitaxially Grown Surface Alloys, Orhan Kizilkaya Jan 2003

Atomic And Electronic Structure Of Bulk Intermetallic And Heteroepitaxially Grown Surface Alloys, Orhan Kizilkaya

LSU Doctoral Dissertations

It has been well documented that the surfaces of solids may differ from their bulk counterpart. The symmetry that a bulk possesses is broken at the surface. Due to this broken symmetry in the reduced dimension of the surface, the energetic of the surface also differs from the bulk counterpart. Reconstruction, charge redistribution, and surface alloying are phenomena that minimize the surface free energy. Surface properties of scientifically and technologically important bimetallic systems are the main focus of this dissertation. Specifically, surfaces of bulk alloy or heteroepitaxially grown metal-on-metal systems have been investigated primarily with two indispensable surface techniques, scanning …


Design And Synthesis Of Constrained Dipeptide Units For Use As Β-Sheet Promoters, Umut Oguz Jan 2003

Design And Synthesis Of Constrained Dipeptide Units For Use As Β-Sheet Promoters, Umut Oguz

LSU Doctoral Dissertations

The study of factors promoting beta-sheet formation has recently gained interest due to the suspected involvement of beta-sheets in brain degenerative diseases such as Alzheimer's disease (AD), Creutzfeldt-Jacob disease (CJD) and bovine spongiform encephalopathy. Understanding beta-sheet formation and the factors that stabilize beta-sheet structure may serve as a basis for future drug design. The extended structure of a beta-sheet can be stabilized by constrained amino acid analogs that are pre-organized to adopt the extended conformation. In this dissertation using innovative synthetic organic chemistry methods, two dipeptide units are designed and synthesized that are constrained to form the extended conformation and …


Design And Synthesis Of Handles For Solid-Phase Peptide Synthesis And Convergent Peptide Synthesis, Jose Giraldes Jan 2003

Design And Synthesis Of Handles For Solid-Phase Peptide Synthesis And Convergent Peptide Synthesis, Jose Giraldes

LSU Doctoral Dissertations

The recent popularity of methods for solid-phase peptide synthesis that use the 9-fluorenylmethyloxycarbonyl (Fmoc) group for Nα-amino protection has created a need for compatible anchoring linkages and handles. In an effort to develop mild new methods for use in solid-phase peptide synthesis (SPPS), a new ferrocene containing linker or “handle”, the 1’1-ferrocenyl carboxaldehyde handle was designed, synthesized, characterized and tested. This linker is analogous to those commercially available and developed by Barany. The ferrocenyl amine linker(FAL) releases C-terminal peptide amides upon acidolysis. Since the FAL handle is acid labile it is compatible with Fmoc and Nα-dithiasuccinoyl …


Group Theoretical Approach To Pairing And Non-Linear Phenomena In Atomic Nuclei, Kristina D. Launey Jan 2003

Group Theoretical Approach To Pairing And Non-Linear Phenomena In Atomic Nuclei, Kristina D. Launey

LSU Doctoral Dissertations

The symplectic sp(4) algebra provides a natural framework for studying proton-neutron (pn) and like-nucleon pairing correlations as well as higher-J pn interactions in nuclei when protons and neutrons occupy the same shell. While these correlations manifest themselves most clearly in the binding energies of 0+ ground states, they also have a large effect on the spectra of excited isobaric analog 0+ states. With a view towards nuclear structure applications, a fermion realization of sp(4) is explored and its q-deformed extension, sp(4)q, is constructed for single and multiple shells. The su(2)(q) substructures that enter are associated with isospin symmetry and with …


Control Of Transport Dynamics In Overlay Networks, Qishi Wu Jan 2003

Control Of Transport Dynamics In Overlay Networks, Qishi Wu

LSU Doctoral Dissertations

Transport control is an important factor in the performance of Internet protocols, particularly in the next generation network applications involving computational steering, interactive visualization, instrument control, and transfer of large data sets. The widely deployed Transport Control Protocol is inadequate for these tasks due to its performance drawbacks. The purpose of this dissertation is to conduct a rigorous analytical study on the design and performance of transport protocols, and systematically develop a new class of protocols to overcome the limitations of current methods. Various sources of randomness exist in network performance measurements due to the stochastic nature of network traffic. …


Angle-Resolved Photoemission Study And Neutron Diffraction Measurements On Lasb2, Alice Acatrinei Jan 2003

Angle-Resolved Photoemission Study And Neutron Diffraction Measurements On Lasb2, Alice Acatrinei

LSU Doctoral Dissertations

LaSb2 has recently been found to have unusual magnetoresistive properties despite the fact that neither La nor Sb are magnetic. The resistance is anisotropic, and at high magnetic fields presents an anomaly that might be a result of a charge density transition. The magnetoresistance is anisotropic and linear, and the resistivity presents high relative changes when a magnetic field is applied. Discovered in 1954, LaSb2, as the rest of the light rare-earth diantimonides, was poorly studied. The anisotropic magnetic properties reported in 1998 by Bud'ko, Canfield and their collaborators make the series very interesting. A description of …


The Extinction Properties Of Reddened Galactic Ob Sightlines, Lynne Angela Valencic Jan 2003

The Extinction Properties Of Reddened Galactic Ob Sightlines, Lynne Angela Valencic

LSU Doctoral Dissertations

A solid understanding of dust grains and their extinction properties is needed to better remove the effects of extinction from data and to comprehend the nature of the processes which modify grains. This requires a large sample of Galactic sightlines, extending far beyond the solar neighborhood, sampling not only a large volume of space but also a wide variety of environments. To fulfill this requirement, a database of sightlines toward 426 young, reddened stars was constructed using extinction curves based on IUE spectra. The curves were fit and the Fitzpatrick-Massa (FM) parameters were found. FM parameters allow for a quantitative …


Massively Parallel Molecular Dynamics Simulations Of Crack-Front Dynamics And Morphology In Amorphous Nanostructured Silica, Cindy Lynn Rountree Jan 2003

Massively Parallel Molecular Dynamics Simulations Of Crack-Front Dynamics And Morphology In Amorphous Nanostructured Silica, Cindy Lynn Rountree

LSU Doctoral Dissertations

Atomistic aspects of dynamic fracture in amorphous and nanostructured silica are herein studied via Molecular dynamics (MD) simulations, ranging from a million to 113 million atom system. The MD simulations were performed on massivelly parallel computers using highly efficient multi-resolution algorithms. Crack propagation in these systems is accompanied by nucleation and growth of nanometer scale cavities up to 20 nm ahead of the crack front. Cavities coalesce and merge with the advancing crack to cause mechanical failure. Recent AFM studies in silica glasses confirm this scenario of fracture [1]. The morphology of the fracture surfaces is studied by calculating the …


Computer Assisted Screening Of Digital Mammogram Images, John Terry Sample Jan 2003

Computer Assisted Screening Of Digital Mammogram Images, John Terry Sample

LSU Doctoral Dissertations

The use of computer systems to assist clinicians in digital mammography image screening has advantages over traditional methods. Computer algorithms can enhance the appearance of the images and highlight suspicious areas. Screening provides a more thorough examination of the images. Any computer system that does screening of digital mammograms contains components to address multiple tasks such as: image segmentation, mass lesion detection and classification, and microcalcification detection and classification. This dissertation provides both effective and efficient improvements to existing algorithms, which segment mammogram images and locate mass lesions. In addition, we provide a new algorithm to evaluate and report the …


Equations Of Parametric Surfaces With Base Points Via Syzygies, Haohao Wang Jan 2003

Equations Of Parametric Surfaces With Base Points Via Syzygies, Haohao Wang

LSU Doctoral Dissertations

Suppose $S$ is a parametrized surface in complex projective 3-space $mathbf{P}^3$ given as the image of $phi: mathbf{P}^1 imes mathbf{P}^1 o mathbf{P}^3$. The implicitization problem is to compute an implicit equation $F=0$ of $S$ using the parametrization $phi$. An algorithm using syzygies exists for computing $F$ if $phi$ has no base points, i.e. $phi$ is everywhere defined. This work is an extension of this algorithm to the case of a surface with multiple base points of total multiplicity k. We accomplish this in three chapters. In Chapter 2, we develop the concept and properties of Castelnuovo-Mumford regularity in biprojective spaces. …


Splitter Theorems For 3- And 4-Regular Graphs, Jinko Kanno Jan 2003

Splitter Theorems For 3- And 4-Regular Graphs, Jinko Kanno

LSU Doctoral Dissertations

Let g be a class of graphs and ≤ be a graph containment relation. A splitter theorem for g under ≤ is a result that claims the existence of a set O of graph operations such that if G and H are in g and HG with GH, then there is a decreasing sequence of graphs from G to H, say G=G0≥G1≥G2...Gt=H, all intermediate graphs are in g, and each Gi can be obtained from Gi-1 by applying a single …


Solid-Phase Dna Sequencing Reactions Performed In Micro-Capillary Reactors And Solid-Phase Reversible Immobilization In Microfluidic Chips For Purification Of Dye-Labeled Dna Sequencing Fragments, Yichuan Xu Jan 2003

Solid-Phase Dna Sequencing Reactions Performed In Micro-Capillary Reactors And Solid-Phase Reversible Immobilization In Microfluidic Chips For Purification Of Dye-Labeled Dna Sequencing Fragments, Yichuan Xu

LSU Doctoral Dissertations

The research presented in this dissertation involves micro-capillary reactors for solid phase DNA sequencing, the identification of dye terminator sequencing fragments with time-resolved methods, and purification of dye-labeled DNA fragments using solid- phase reversible immobilization in microfluidic chips. Solid-phase micro-reactors have been prepared for DNA sequencing applications using slab gel electrophoresis. A PCR product was immobilized to the interior wall of a fused-silica capillary tube via a biotin-streptavidin linkage. Solid-phase sequencing was carried out in micro-capillary reactors using a four-lane, single color dye primer chemistry strategy. The read length was found to be 589 bases. The complementary DNA fragments generated …


Toward A Global Microscopic Theory For Nuclear Structure: Mean Field Plus Random Phase Approximation Vs. Shell Model, Ionel Stetcu Jan 2003

Toward A Global Microscopic Theory For Nuclear Structure: Mean Field Plus Random Phase Approximation Vs. Shell Model, Ionel Stetcu

LSU Doctoral Dissertations

Our understanding of nuclear structure is built upon mean-field theories such as Hartree-Fock and time-dependent Hartree-Fock. The small-amplitude limit of the latter is the random phase approximation (RPA), which is widely used to model giant resonances in nuclei. Despite this popularity, RPA has been mostly validated against toy models; tests against complex models are scarce in the literature. We perform a thorough test of the RPA against full 0hw shell model (SM) calculations, including in our investigation binding energies, scalar ground-state observables, for which we develop a new method, and transition strengths. We allow deformed Hartree-Fock solutions and compare results …


Parallel Molecular Dynamics Simulations Of Dynamics Of Oxidation And Reactive Wetting In Metal/Ceramic Systems, Gurcan Aral Jan 2003

Parallel Molecular Dynamics Simulations Of Dynamics Of Oxidation And Reactive Wetting In Metal/Ceramic Systems, Gurcan Aral

LSU Doctoral Dissertations

Oxidation of a flat aluminum (111) surface and the reactive wetting of the aluminum (Al) droplet on a flat alumina (α-Al2O3) surface are investigated by using parallel molecular-dynamics simulations with dynamic charge transfer among atoms on a microscopic length scale. The interatomic potential, based on the formalism of Streitz and Mintmire, allows atoms to vary their charges dynamically between anions and cations, when atoms move and their local environment is altered. We investigate the oxidation thickness as a function of time and the oxygen density which is 10-40 times that of the normal state (1 atm …


Molecular-Dynamics Simulations Of Self-Assembled Monolayers (Sam) On Parallel Computers, Satyavani Vemparala Jan 2003

Molecular-Dynamics Simulations Of Self-Assembled Monolayers (Sam) On Parallel Computers, Satyavani Vemparala

LSU Doctoral Dissertations

The purpose of this dissertation is to investigate the properties of self-assembled monolayers, particularly alkanethiols and Poly (ethylene glycol) terminated alkanethiols. These simulations are based on realistic interatomic potentials and require scalable and portable multiresolution algorithms implemented on parallel computers. Large-scale molecular dynamics simulations of self-assembled alkanethiol monolayer systems have been carried out using an all-atom model involving a million atoms to investigate their structural properties as a function of temperature, lattice spacing and molecular chain-length. Results show that the alkanethiol chains tilt from the surface normal by a collective angle of 25o along next-nearest neighbor direction at 300K. At …


A Comparison Of Life Histories And Ecological Aspects Among Snappers (Pisces: Lutjanidae), Fernando Martinez-Andrade Jan 2003

A Comparison Of Life Histories And Ecological Aspects Among Snappers (Pisces: Lutjanidae), Fernando Martinez-Andrade

LSU Doctoral Dissertations

An extensive search for data on life-history and ecological variables was conducted for a representative number of the species within the family Lutjanidae. After creating different databases and standardizing all data, these variables were examined in statistical, correlation and graphic analyses. Additionally, a series of Principal Component Analyses were used to examine patterns among variables. Life-history variables included age at length zero, asymptotic length, maximum length, longevity, asymptotic weight, length at maturity, age at maturity, reproductive life span, growth rate and mortality rate. Ecological variables included latitudinal and vertical distribution, habitat selection (represented by substrate type), and spawning seasons. The …


Biomechanical Reconstruction Of The Appendicular Skeleton In Three North American Jurassic Sauropods, Ray Wilhite Jan 2003

Biomechanical Reconstruction Of The Appendicular Skeleton In Three North American Jurassic Sauropods, Ray Wilhite

LSU Doctoral Dissertations

Forelimb and hindlimb articulation, reconstructed musculature, and function were examined in Apatosaurus, Diplodocus, and Camarasaurus. A technique was developed using a Microscribe three-dimensional digitizer to capture external morphological data for skeletal reconstruction and determination of taxonomically useful features. The appendicular musculature of Alligator mississippiensis was dissected to determine form, function, origin, and insertion of muscles to aid in reconstruction of sauropod musculature. Contrary to the literature, M. caudofemoralis longus was found to originate primarily from the lateral surfaces of the proximal chevrons instead of the bodies and transverse processes of the caudals, demonstrating that chevron morphology is indicative of the …


Synthesis, Characterization, And Application Of Water-Soluble Chiral Calix[4]Arene Derivatives In Spectroscopy And Capillary Electrokinetic Chromatography, Kim Hamilton Jan 2003

Synthesis, Characterization, And Application Of Water-Soluble Chiral Calix[4]Arene Derivatives In Spectroscopy And Capillary Electrokinetic Chromatography, Kim Hamilton

LSU Doctoral Dissertations

This dissertation is an account of the synthesis, characterization, and application of novel water-soluble chiral calixarenes in spectroscopy and capillary electrophoresis. It is divided into four sections. The first part describes the synthesis and nuclear magnetic resonance (NMR) characterization of four p-t-butylcalix[4]arenes bearing L-amino acid moieties on their lower rims (CX4-AA). The structure and conformation of the derivatives have been determined using one- and two-dimensional NMR techniques. Proton and carbon-13 spectra show that the derivatives are tetra-substituted and adopt a cone conformation. The preparation and characterization of silica-bonded calixarene stationary phases for capillary electrochromatography is also reported in Chapter 2. …


Abundance Trends And Environmental Habitat Usage Patterns Of Bottlenose Dolphins (Tursiops Truncatus) In Lower Barataria And Caminada Bays, Louisiana, Cara Edina Miller Jan 2003

Abundance Trends And Environmental Habitat Usage Patterns Of Bottlenose Dolphins (Tursiops Truncatus) In Lower Barataria And Caminada Bays, Louisiana, Cara Edina Miller

LSU Doctoral Dissertations

The paucity of research into the environmental requirements, stock membership, abundance and residency patterns of bottlenose dolphins (Tursiops truncatus) in coastal Louisiana creates difficulty in understanding how local ecosystems and threats (such as fishery interactions, habitat degradation and pollution) affect populations. This study combined fine-scale environmental measurements and photo-identification techniques to describe patterns of habitat usage and abundance of bottlenose dolphins in lower Barataria Basin from June 1999 to May 2002. In addition I investigated the validity and limitations of using mark-recapture models to estimate abundance from cetacean photo-identification data. Bottlenose dolphins were present year-round in a wide range of …


Design, Synthesis, And Applications Of Bio-Derived Crosslinking Monomers For Molecular Imprinting, Martha Sibrian-Vazquez Jan 2003

Design, Synthesis, And Applications Of Bio-Derived Crosslinking Monomers For Molecular Imprinting, Martha Sibrian-Vazquez

LSU Doctoral Dissertations

Most of the research in the field of molecular imprinting has been focused on the development of new functional monomers, in order to improve the molecular recognition properties afforded by these materials. The role of the crosslinking monomer has often been overlooked, since it is considered an inert component that only provides a scaffold to support the binding sites. However, the crosslinking monomer represents a high percent (80-90%) of the composition of molecularly imprinted polymers (MIPs), which can have a large influence on the MIPs properties. This research addresses the design, synthesis, and applications of new crosslinking monomers for molecular …


Machine Learning Techniques For Efficient Query Processing In Kowledge Base Systems, Kevin Paul Grant Jan 2003

Machine Learning Techniques For Efficient Query Processing In Kowledge Base Systems, Kevin Paul Grant

LSU Doctoral Dissertations

In this dissertation we propose a new technique for efficient query processing in knowledge base systems. Query processing in knowledge base systems poses strong computational challenges because of the presence of combinatorial explosion. This arises because at any point during query processing there may be too many subqueries available for further exploration. Overcoming this difficulty requires effective mechanisms for choosing from among these subqueries good subqueries for further processing. Inspired by existing works on stochastic logic programs, compositional modeling and probabilistic heuristic estimates we create a new, nondeterministic method to accomplish the task of subquery selection for query processing. Specifically, …


The Kauffman Bracket Skein Module Of The Quaternionic Manifold, John Michael Harris Jan 2003

The Kauffman Bracket Skein Module Of The Quaternionic Manifold, John Michael Harris

LSU Doctoral Dissertations

In this work, we study the structure of the Kauffman bracket skein module of the quaternionic manifold over the field of rational functions. We begin with a brief survey of manifolds whose Kauffman bracket skein modules are known, and proceed in Chapter 2 by recalling the facts from Temperley-Lieb recoupling theory that we use in the proofs. In Chapter 3, using recoupling theory and with Mathematica's assistance, we index an infinite presentation of the skein module, and conjecture that it is five-dimensional. In Chapter 4, using a new set of relations, we prove that the skein module is indeed spanned …


Book Embeddings Of Graphs, Robin Leigh Blankenship Jan 2003

Book Embeddings Of Graphs, Robin Leigh Blankenship

LSU Doctoral Dissertations

We use a structural theorem of Robertson and Seymour to show that for every minor-closed class of graphs, other than the class of all graphs, there is a number k such that every member of the class can be embedded in a book with k pages. Book embeddings of graphs with relation to surfaces, vertex extensions, clique-sums and r-rings are combined into a single book embedding of a graph in the minor-closed class. The effects of subdividing a complete graph and a complete bipartite graph with respect to book thickness are studied. We prove that if n ≥ 3, …