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Effects Of Insulin And Insulin Mimetics On Antioxidant Enzyme Levels: In Vivo And In Vitro, Shikha Varma
Effects Of Insulin And Insulin Mimetics On Antioxidant Enzyme Levels: In Vivo And In Vitro, Shikha Varma
Masters Theses
Tissue antioxidation status is considered to be an important factor for elucidating the etiology of diabetes and its physiological complications. This study was aimed to determine the in vivo antioxidant enzyme levels in the altered antioxidant status of diabetic rat liver with the treatment of two potent insulin mimetics, vanadium and selenate. The direct effects of vanadate, selenate, and zinc (another insulin mimetic) on the antioxidant enzyme levels in primary rat hepatocytes in culture was also determined. Levels of superoxide dismutase (SOD), catalase (CAT) and gluthahione peroxidase (GPX) were determined in both model systems.
In the vivo model, insulin treatment …
Evaluation Of Bail-Down Test Methods For Characterizing Free Product Recoverability From An Aquifer, Laura L. Krol
Evaluation Of Bail-Down Test Methods For Characterizing Free Product Recoverability From An Aquifer, Laura L. Krol
Masters Theses
Determination of the occurrence and recoverability of free product impacting the subsurface environment has been an on-going challenge in the environmental industry. A simple and relatively inexpensive test to perform in the field is the free product bail-down test. Many authors have proposed various analysis methods using these data for the determination of different free product characteristics.
The purpose of this project was to determine the comparability and possible validity of bail-down test interpretation methods for predicting hydrocarbon hydraulic conductivity/transmissivity and true free product thickness. Bail-down test data collected from two sites were analyzed and interpreted using methods from the …
A Study On The Causes Of Variations In Transmissivity And Storativity During Pump Tests At Asylum Lake, Paul Joseph Pare
A Study On The Causes Of Variations In Transmissivity And Storativity During Pump Tests At Asylum Lake, Paul Joseph Pare
Masters Theses
Over a two year period, Western Michigan University ran a number of pump tests in the Asylum Lake Area in Kalamazoo, Michigan. The transmissivities and storativities calculated from these tests differed significantly from well to well in any particular test, and from pump test to pump test. Utilizing the computer programs AQTESOLV 3.0 and Aquifer Parameter Estimator, a number of T and S values were calculated. After analysis of the results, the following conclusion was drawn. The main reason for the deviations in the T and S values arose from the mixing of the results of numerous methods (some of …
Band Structure For Acoustic Waves Propagating In A Periodic Elastic Media And Impurity Modes Arising From Slab Substitutions, Abdur Rahman
Band Structure For Acoustic Waves Propagating In A Periodic Elastic Media And Impurity Modes Arising From Slab Substitutions, Abdur Rahman
Masters Theses
In this thesis I study the band structure for acoustic waves propagating in a one-dimensional elastic array which forms a periodic elastic system in which band gaps are opened in the frequency spectrum. Specifically, I study the single impurity problem in this system. An impurity is introduced in the system by replacing one of the acoustic slabs with a new slab of different acoustic medium or by changing the thickness of impurity slab. I study the very narrow (in frequency) impurity modes in the band gaps which are localized about the impurity sites. Then I study the frequency of impurity …
Regulation Of The Expression Of Lipogenic Enzymes By Insulin-Mimetics, Juiyu Wu
Regulation Of The Expression Of Lipogenic Enzymes By Insulin-Mimetics, Juiyu Wu
Masters Theses
Many researchers have shown that selenate (SeO42-) and vanadate (VO42-) have insulin-mimetic effects in certain biological processes. These mimetic effects include increasing glucose transport, regulating glycolytic enzymes, normalizing plasma glucose levels and activities of insulin regulated enzymes in diabetic rats. To clarify the functions and roles of these insulin-mimetics in different insulin-regulated metabolic pathways, the expression of the genes for glucose-6-phosphate dehydrogenase (G6PDH) and fatty acid synthase (FAS) were investigated. G6PDH is a key enzyme in the pentose phosphate pathway and is also involved in lipogenic metabolism by providing 55-70% of the NADPH utilization …
The Variability Of Carbon Dioxide In The Vadose Zone, John J. Ring
The Variability Of Carbon Dioxide In The Vadose Zone, John J. Ring
Masters Theses
The purpose of this thesis was to observe and attempt to explain the variations of carbon dioxide in the vadose zone of a nature area in southwestern Michigan. Well nests, consisting of discrete soil gas sampling points and temperature probes set at depths ranging from 3 to 53 feet, were constructed in a sandy, glacial outwash plain. Soil samples were collected for analysis of organic carbon content during installation. Soil gas samples were collected periodically from June, 1992 to March, 1993 and analyzed for CO2 and O2 concentrations. Occasionally, samples were collected and analyzed for isotopic C13 …
The Effects Of Air Sparging On Aquifer Hydraulic Conductivity, Hans Neve
The Effects Of Air Sparging On Aquifer Hydraulic Conductivity, Hans Neve
Masters Theses
Air sparging is a relatively new technology used to remove organic contaminants from aquifers. This remediation technique involves injecting into contaminated portions of water table aquifers. Theoretically air sparging will reduce aquifer hydraulic conductivity. Injected air fills some of the available sediment pores, thus restricting the flow of water to the remaining water-filled pore spaces.
The purpose of this study was to measure the reduction in hydraulic conductivity due to air sparging. This was assessed using both laboratory and field techniques. The hydraulic conductivities of several different sediments were determined in the laboratory using a large constant head permeameter modified …
A Comparison Of Methods To Allocate Tasks On A Multiprocessor System, Kelly Cousineau
A Comparison Of Methods To Allocate Tasks On A Multiprocessor System, Kelly Cousineau
Masters Theses
The task scheduling problem is defined as a sequential algorithm, with individual tasks, t1, t2, t3… having associated execution times to be ported to a multiprocessor system. To determine the fastest parallel implementation is known to be an NP-complete problem, therefore heuristic techniques are employed to arrive at the best solution.
Some of the traditional methods used to solve this problem, are the list scheduling algorithm and the simulated annealing algorithm. However, evolutionary techniques are now also a consideration with the increased computation power available.
Evolutionary techniques, based on the popular theory of evolution, …
Planar Over The Cell Routing, Srinivasa R. Danda
Planar Over The Cell Routing, Srinivasa R. Danda
Masters Theses
Planar over the cell routing in standard cell layouts is an important problem and it has been studied quite extensively. In two layer standard cell design methodology, Ml layer is typically used for connections internal to the cell, and the M2 layer is available for routing over-the-cell. In this thesis, we consider the Two Row Maximum Planar Subset (TRMPS) problem in Over-The-Cell routing. The TRMPS problem requires selection of the maximum planar subset of nets, which can be routed between two rows of terminals in a cell row. This problem was first encountered by Cong, Liu, and Preas [3]. They …
A Unified Approach To Multilayer Routing, Sreekrishna Madhwapathy
A Unified Approach To Multilayer Routing, Sreekrishna Madhwapathy
Masters Theses
Several Over-the-Cell (OTC) routing algorithms have been proposed for two and three layer processes. All the existing OTC routers assume that the terminals are laid out in a specific predetermined fashion. These restrictions on the terminals complicate the task of cell design and increase the width of the cells.
In this thesis, we report two results. First, we present a new layout methodology, for obtaining minimum width cells, with arbitrarily located terminals. Next, we develop a multilayer routing approach, which is independent of the cell model used in the layout design. Freed from fixed terminal placement restrictions, cell designers can …
Structural Effects On Micellar Catalyzed Hydrolysis Of Hydroxamic Acids With Perfluorooctanoic Acid As Surfactant, Xing Zhang
Masters Theses
This thesis demonstrated the structural effects on micellar catalyzed hydrolysis of hydroxamic acids with prefluorooctanoic acid as the reactive counterion surfactant in aqueous acetonitrile solution.
For different hydroxamic acids, the observed pseudo-first order rate constant-surfactant concentration profiles were obtained and were used in the determination of critical micellar concentrations (cmc).
The micellar catalytic effect was satisfactorily explained by the pseudo-phase ion exchange (PPIE) model. The PPIE model was successfully applied in the determination of the reaction rate constants both in the water phase and in micellar pseudo-phase.
Further investigation into more appropriate hydroxamic acids is suggested in order to obtain …
A Feasibility Study For Using Computerized Water Well Records To Delineate Areas Of Recharge-Discharge Potential, Lauren D. Hughes
A Feasibility Study For Using Computerized Water Well Records To Delineate Areas Of Recharge-Discharge Potential, Lauren D. Hughes
Masters Theses
A method for delineating areas of recharge-discharge potential has been developed utilizing computerized water well records. The methodology is based on the vertical head differences found between wells with shallow depths of submergence and those with deeper depths of submergence. The residual values generated represent the magnitude of vertical potential and can be contoured to delineate areas of recharge-discharge potential. Well data were obtained from the Kalamazoo County Groundwater Database. Well selection was based on depth of submergence and total well depth.
The methodology was tested in Texas and Schoolcraft Townships, the Donnell Lake Study Area, and Kalamazoo County. Regularly …
Hydrogeochemical Delineation Of A Groundwater Flow System, Berrien County, Michigan, Patrick J. Bartnik
Hydrogeochemical Delineation Of A Groundwater Flow System, Berrien County, Michigan, Patrick J. Bartnik
Masters Theses
The objective of this study was to examine the possibility of determining groundwater flow directions from natural variations in groundwater chemistry. Groundwater samples were analyzed for major cation and anion concentrations. These data were to have been contoured and then compared with groundwater flow maps generated by conventional methods. The purpose was to determine whether a correlation could be drawn between the two methods. However, the results of the study did not allow for this comparison.
The plotted major cation and anion data did not lend themselves to contouring, which suggests that greater control may be required during the selection …
An Experimental Apparatus For Studying Differential Scattering Of Multiply-Charged Ions From Neutral Targets Following Capture, John Edward Edens
An Experimental Apparatus For Studying Differential Scattering Of Multiply-Charged Ions From Neutral Targets Following Capture, John Edward Edens
Masters Theses
An experimental apparatus has been designed, enabling measurement of angular differential cross sections for single-electron capture (SEC). The design consists of a microchannel plate detector with a one-dimensional position sensitive anode. A bow-time shaped aperture was employed to convert a radially scattered distribution into an approximate linear one. An electrostatic retarding grid was used to separate SEC contributions from the reaction products. Measurements were made of the angular differential cross sections for SEC of Arq+ (q=4-6,8) ions scattering from He and Ar at impact energies of 600 to 3000 eV and angles between 0 and 23 mrad. The experimental …
Geophysical Investigation At The Mouth Of The St. Joseph River Valley And Adjacent Lake Michigan Shoreline In St. Joseph And Benton Harbor, Michigan, David L. Seng
Masters Theses
A combination of geophysical methods were employed in an attempt to characterize a small section of the shoreline of the St. Joseph, Michigan, region of the Lake Michigan shoreline. Electrical resistivity and Ground Penetrating Radar profiles conducted along the shoreline and within the nearshore environment reveal a buried valley of the ancestral St. Joseph river. This valley represents incision of the channel during lowered lake levels at the end of the Pleistocene.
Lakeward dipping radar reflectors are identified throughout the study site. Within the buried valley the reflectors are not glacial till as is the case outside the inferred valley …