Digital Commons Network^™

Prevention Of Poxvirus Infection By Tetrapyrroles, Avril Rm Chen-Collins, Dabney W. Dixon, Andrei N. Vzorov, Luigi G. Marzilli, Richard W. Compans

Chemistry Faculty Publications

Background: Prevention of poxvirus infection is a topic of great current interest. We report inhibition of vaccinia virus in cell culture by porphyrins and phthalocyanines. Most previous work on the inhibition of viruses with tetrapyrroles has involved photodynamic mechanisms. The current study, however, investigates light-independent inhibition activity.

Methods: The Western Reserve (WR) and International Health Department-J (IHD-J) strains of vaccinia virus were used. Virucidal and antiviral activities as well as the cytotoxicity of test compounds were determined.

Results: Examples of active compounds include zinc protoporphyrin, copper hematoporphyrin, meso(2,6-dihydroxyphenyl)porphyrin, the sulfonated tetra-1-naphthyl and tetra-1- anthracenylporphyrins, selected sulfonated derivatives of halogenated tetraphenyl …

Multicasting In Multihop Optical Wdm Networks With Limited Wavelength Conversion, Hong Shen, Yi Pan, John Sum, Susumu Horiguchi

Computer Science Faculty Publications

This paper provides an overview on efficient algorithms for multicasting in optical networks supported by Wavelength Division Multiplexing (WDM) with limited wavelength conversion. We classify the multicast problems according to off-line and on-line in both reliable and unreliable networks. In each problem class, we present efficient algorithms for multicast and multiple multicast and show their performance. We also present efficient schemes for dynamic multicast group membership updating. We conclude the paper by showing possible extension of the presented algorithms for QoS provision.