Digital Commons Network^™

Towards Safe Automated Refactoring Of Imperative Deep Learning Programs To Graph Execution, Raffi Takvor Khatchadourian Ph.D., Tatiana Castro Vélez, Mehdi Bagherzadeh, Nan Jia, Anita Raja

Publications and Research

Efficiency is essential to support responsiveness w.r.t. ever-growing datasets, especially for Deep Learning (DL) systems. DL frameworks have traditionally embraced deferred execution-style DL code—supporting symbolic, graph-based Deep Neural Network (DNN) computation. While scalable, such development is error-prone, non-intuitive, and difficult to debug. Consequently, more natural, imperative DL frameworks encouraging eager execution have emerged at the expense of run-time performance. Though hybrid approaches aim for the “best of both worlds,” using them effectively requires subtle considerations to make code amenable to safe, accurate, and efficient graph execution. We present our ongoing work on automated refactoring that assists developers in specifying whether …

Towards Safe Automated Refactoring Of Imperative Deep Learning Programs To Graph Execution, Raffi T. Khatchadourian Ph,D,, Tatiana Castro Vélez, Mehdi Bagherzadeh, Nan Jia, Anita Raja

Publications and Research

Efficiency is essential to support responsiveness w.r.t. ever-growing datasets, especially for Deep Learning (DL) systems. DL frameworks have traditionally embraced deferred execution-style DL code—supporting symbolic, graph-based Deep Neural Network (DNN) computation. While scalable, such development is error-prone, non-intuitive, and difficult to debug. Consequently, more natural, imperative DL frameworks encouraging eager execution have emerged at the expense of run-time performance. Though hybrid approaches aim for the "best of both worlds," using them effectively requires subtle considerations to make code amenable to safe, accurate, and efficient graph execution. We present our ongoing work on automated refactoring that assists developers in specifying whether …

A Tool-Supported Metamodel For Program Bugfix Analysis In Empirical Software Engineering, Manal Zneit

Theses and Dissertations

This thesis describes a software modeling approach aimed at addressing empirical studies in software engineering. We build a metamodel that provides an overview of the taxonomy of program bugfixes in deep learning programs. For modeling purposes, we present a prototype tool that is an implementation of the model-driven techniques presented.

Challenges In Migrating Imperative Deep Learning Programs To Graph Execution: An Empirical Study, Tatiana Castro Vélez, Raffi T. Khatchadourian, Mehdi Bagherzadeh, Anita Raja

Publications and Research

Efficiency is essential to support responsiveness w.r.t. ever-growing datasets, especially for Deep Learning (DL) systems. DL frameworks have traditionally embraced deferred execution-style DL code that supports symbolic, graph-based Deep Neural Network (DNN) computation. While scalable, such development tends to produce DL code that is error-prone, non-intuitive, and difficult to debug. Consequently, more natural, less error-prone imperative DL frameworks encouraging eager execution have emerged at the expense of run-time performance. While hybrid approaches aim for the "best of both worlds," the challenges in applying them in the real world are largely unknown. We conduct a data-driven analysis of challenges—and resultant bugs—involved …

Diagnosis Of Polypoidal Choroidal Vasculopathy From Fluorescein Angiography Using Deep Learning, Yu-Yeh Tsai, Wei-Yang Ling, Shih-Jen Chen, Paisan Ruamviboonsuk, Cheng-Ho King, Chia-Ling Tsai

Publications and Research

Purpose: To differentiate polypoidal choroidal vasculopathy (PCV) from choroidal neovascularization (CNV) and to determine the extent of PCV from fluorescein angiography (FA) using attention-based deep learning networks.

Methods: We build two deep learning networks for diagnosis of PCV using FA, one for detection and one for segmentation. Attention-gated convolutional neural network (AG-CNN) differentiates PCV from other types of wet age-related macular degeneration. Gradient-weighted class activation map (Grad-CAM) is generated to highlight important regions in the image for making the prediction, which offers explainability of the network. Attention-gated recurrent neural network (AG-PCVNet) for spatiotemporal prediction is applied for segmentation …

Diagnosis Of Polypoidal Choroidal Vasculopathy From Fluorescein Angiography Using Deep Learning, Yu-Yeh Tsai, Wei-Yang Lin, Shih-Jen Chen, Paisan Ruamviboonsuk, Cheng-Ho King, Chia-Ling Tsai

Publications and Research

Purpose: To differentiate polypoidal choroidal vasculopathy (PCV) from choroidal neovascularization (CNV) and to determine the extent of PCV from fluorescein angiography (FA) using attention-based deep learning networks.

Methods: We build two deep learning networks for diagnosis of PCV using FA, one for detection and one for segmentation. Attention-gated convolutional neural network (AG-CNN) differentiates PCV from other types of wet age-related macular degeneration. Gradient-weighted class activation map (Grad-CAM) is generated to highlight important regions in the image for making the prediction, which offers explainability of the network. Attention-gated recurrent neural network (AG-PCVNet) for spatiotemporal prediction is applied for segmentation of PCV. …

Treatment Selection Using Prototyping In Latent-Space With Application To Depression Treatment, Akiva Kleinerman, Ariel Rosenfeld, David Benrimoh, Robert Fratila, Caitrin Armstrong, Joseph Mehltretter, Eliyahu Shneider, Amit Yaniv-Rosenfeld, Jordan Karp, Charles F. Reynolds, Gustavo Turecki, Adam Kapelner

Publications and Research

Machine-assisted treatment selection commonly follows one of two paradigms: a fully personalized paradigm which ignores any possible clustering of patients; or a sub-grouping paradigm which ignores personal differences within the identified groups. While both paradigms have shown promising results, each of them suffers from important limitations. In this article, we propose a novel deep learning-based treatment selection approach that is shown to strike a balance between the two paradigms using latent-space prototyping. Our approach is specifically tailored for domains in which effective prototypes and sub-groups of patients are assumed to exist, but groupings relevant to the training objective are not …

Covid-19 Multi-Targeted Drug Repurposing Using Few-Shot Learning, Yang Liu, You Wu, Xiaoke Shen, Lei Xie

Publications and Research

The life-threatening disease COVID-19 has inspired significant efforts to discover novel therapeutic agents through repurposing of existing drugs. Although multi-targeted (polypharmacological) therapies are recognized as the most efficient approach to system diseases such as COVID-19, computational multi-targeted compound screening has been limited by the scarcity of high-quality experimental data and difficulties in extracting information from molecules. This study introduces MolGNN , a new deep learning model for molecular property prediction. MolGNN applies a graph neural network to computational learning of chemical molecule embedding. Comparing to state-of-the-art approaches heavily relying on labeled experimental data, our method achieves equivalent or superior prediction …

A Semi-Automated Approach To Medical Image Segmentation Using Conditional Random Field Inference, Yu-Chi Hu

Dissertations, Theses, and Capstone Projects

Medical image segmentation plays a crucial role in delivering effective patient care in various diagnostic and treatment modalities. Manual delineation of target volumes and all critical structures is a very tedious and highly time-consuming process and introduce uncertainties of treatment outcomes of patients. Fully automatic methods holds great promise for reducing cost and time, while at the same time improving accuracy and eliminating expert variability, yet there are still great challenges. Legally and ethically, human oversight must be integrated with ”smart tools” favoring a semi-automatic technique which can leverage the best aspects of both human and computer.

In this work …

Does Applying Deep Learning In Financial Sentiment Analysis Lead To Better Classification Performance?, Tao Wang, Changhe Yuan, Cuiyuan Wang

Publications and Research

Using a unique data set from Seeking Alpha, we compare the deep learning approach with traditional machine learning approaches in classifying financial text. We apply the long short-term memory (LSTM) as the deep learning method and Naive Bayes, SVM, Logistic Regression, XGBoost as the traditional machine learning approaches. The results suggest that the LSTM model outperforms the conventional machine learning methods on all metrics. Based on the tSNE graph, the success of the LSTM model is partially explained as the high-accuracy LSTM model distinguishes between positive and negative important sentiment words while those words are chosen based on SHAP values …

Semi-Supervised Regression With Generative Adversarial Networks Using Minimal Labeled Data, Greg Olmschenk

Dissertations, Theses, and Capstone Projects

This work studies the generalization of semi-supervised generative adversarial networks (GANs) to regression tasks. A novel feature layer contrasting optimization function, in conjunction with a feature matching optimization, allows the adversarial network to learn from unannotated data and thereby reduce the number of labels required to train a predictive network. An analysis of simulated training conditions is performed to explore the capabilities and limitations of the method. In concert with the semi-supervised regression GANs, an improved label topology and upsampling technique for multi-target regression tasks are shown to reduce data requirements. Improvements are demonstrated on a wide variety of vision …

Personality Recognition For Deception Detection, Guozhen An

Dissertations, Theses, and Capstone Projects

Personality aims at capturing stable individual characteristics, typically measurable in quantitative terms, that explain and predict observable behavioral differences. Personality has been proved to be very useful in many life outcomes, and there has been huge interests on predicting personality automatically. Previously, there are tremendous amount of approaches successfully predicting personality. However, most previous research on personality detection has used personality scores assigned by annotators based solely on the text or audio clip, and found that predicting self-reported personality is a much more difficult task than predicting observer-report personality. In our study, we will demonstrate how to accurately detect self-reported …

Object Localization, Segmentation, And Classification In 3d Images, Allan Zelener

Dissertations, Theses, and Capstone Projects

We address the problem of identifying objects of interest in 3D images as a set of related tasks involving localization of objects within a scene, segmentation of observed object instances from other scene elements, classifying detected objects into semantic categories, and estimating the 3D pose of detected objects within the scene. The increasing availability of 3D sensors motivates us to leverage large amounts of 3D data to train machine learning models to address these tasks in 3D images. Leveraging recent advances in deep learning has allowed us to develop models capable of addressing these tasks and optimizing these tasks jointly …

Exploring The Internal Statistics: Single Image Super-Resolution, Completion And Captioning, Yang Xian

Dissertations, Theses, and Capstone Projects

Image enhancement has drawn increasingly attention in improving image quality or interpretability. It aims to modify images to achieve a better perception for human visual system or a more suitable representation for further analysis in a variety of applications such as medical imaging, remote sensing, and video surveillance. Based on different attributes of the given input images, enhancement tasks vary, e.g., noise removal, deblurring, resolution enhancement, prediction of missing pixels, etc. The latter two are usually referred to as image super-resolution and image inpainting (or completion).

Image super-resolution and completion are numerically ill-posed problems. Multi-frame-based approaches make use of the …