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Some Contributions In Statistical Discrimination Of Different Pathogens Using Observations Through Ftir, Dongmei Wang Dec 2009

Some Contributions In Statistical Discrimination Of Different Pathogens Using Observations Through Ftir, Dongmei Wang

Mathematics Theses

Fourier Transform Infrared (FTIR) has been use to discriminate different pathogens by signals from cells infected with these versus normal cells as references. To do the statistical analysis, Partial Least Square Regression (PLSR) was utilized to distinguish any two kinds of virus‐infected cells and normal cells. Validation using Bootstrap method and Cross‐validations were employed to calculate the shrinkages of Area Under the ROC Curve (AUC) and specificities corresponding to 80%, 90%, and 95% sensitivities. The result shows that our procedure can significantly discriminate these pathogens when we compare infected cells with the normal cells. On the height of this success, …


Advanced Statistical Methodologies In Determining The Observation Time To Discriminate Viruses Using Ftir, Shan Luo Jul 2009

Advanced Statistical Methodologies In Determining The Observation Time To Discriminate Viruses Using Ftir, Shan Luo

Mathematics Theses

Fourier transform infrared (FTIR) spectroscopy, one method of electromagnetic radiation for detecting specific cellular molecular structure, can be used to discriminate different types of cells. The objective is to find the minimum time (choice among 2 hour, 4 hour and 6 hour) to record FTIR readings such that different viruses can be discriminated. A new method is adopted for the datasets. Briefly, inner differences are created as the control group, and Wilcoxon Signed Rank Test is used as the first selecting variable procedure in order to prepare the next stage of discrimination. In the second stage we propose either partial …


Correction To Variations Of Ice Bed Coupling Beneath And Beyond Ice Streams: The Force Balance, Terence J. Hughes Jan 2009

Correction To Variations Of Ice Bed Coupling Beneath And Beyond Ice Streams: The Force Balance, Terence J. Hughes

Earth Science Faculty Scholarship

A geometrical force balance that links stresses to ice bed coupling along a flow band of an ice sheet was developed in 1988 for longitudinal tension in ice streams and published 4 years later. It remains a work in progress. Now gravitational forces balanced by forces producing tensile, compressive, basal shear, and side shear stresses are all linked to ice bed coupling by the floating fraction phi of ice that produces the concave surface of ice streams. These lead inexorably to a simple formula showing how phi varies along these flow bands where surface and bed topography are known: phi …


The Effect Of Bacteria On The Sensitivity Of Microalgae To Copper In Laboratory Bioassays, Jacqueline Levy, Jenny L. Stauber, Steven A. Wakelin, Dianne F. Jolley Jan 2009

The Effect Of Bacteria On The Sensitivity Of Microalgae To Copper In Laboratory Bioassays, Jacqueline Levy, Jenny L. Stauber, Steven A. Wakelin, Dianne F. Jolley

Faculty of Science - Papers (Archive)

Although single-species laboratory toxicity tests with microalgae are sensitive and highly reproducible, they lack environmental realism. Interactions between algae and their associated bacteria, either in the plankton or in biofilms, may alter algal sensitivity to contaminants, which are not mimicked in laboratory toxicity tests. This study investigated the effects of simple algal-bacterial relationships on the sensitivity of laboratory-cultured algae to copper using 72-h algal growth-rate inhibition bioassays. Four species of microalgae were used, two isolates of each; a strain of algae with no microscopically visible and no culturable bacteria present (operationally defined as axenic) and a non-axenic strain. The four …


A Chemical Ionization Mass Spectrometer For Continuous Underway Shipboard Analysis Of Dimethylsulfide In Near-Surface Seawater, Eric S. Saltzman, Warren J. De Bruyn, M. J. Lawler, Christa Marandino, C. A. Mccormick Jan 2009

A Chemical Ionization Mass Spectrometer For Continuous Underway Shipboard Analysis Of Dimethylsulfide In Near-Surface Seawater, Eric S. Saltzman, Warren J. De Bruyn, M. J. Lawler, Christa Marandino, C. A. Mccormick

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

A compact, low-cost atmospheric pressure, chemical ionization mass spectrometer ('mini-CIMS') has been developed for continuous underway shipboard measurements of dimethylsulfide (DMS) in seawater. The instrument was used to analyze DMS in air equilibrated with flowing seawater across a porous Teflon membrane equilibrator. The equilibrated gas stream was diluted with air containing an isotopically-labeled internal standard. DMS is ionized at atmospheric pressure via proton transfer from water vapor, then declustered, mass filtered via quadrupole mass spectrometry, and detected with an electron multiplier. The instrument described here is based on a low-cost residual gas analyzer (Stanford Research Systems), which has been modified …


Simulation Of Boundary Layer Trajectory Dispersion Sensitivity To Soil Moisture Conditions: Mm5 And Noah-Based Investigation, Rezaul Mahmood Jan 2009

Simulation Of Boundary Layer Trajectory Dispersion Sensitivity To Soil Moisture Conditions: Mm5 And Noah-Based Investigation, Rezaul Mahmood

School of Natural Resources: Faculty Publications

No abstract provided.