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Physical Sciences and Mathematics

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Theses

2006

Electroanalytical methods

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Development Of Electroanalytical Methods For The Determination Of Sialic Acid As A Biomarker For Cancer, Khawla Ali Rashid Al-Tayyari Jan 2006

Development Of Electroanalytical Methods For The Determination Of Sialic Acid As A Biomarker For Cancer, Khawla Ali Rashid Al-Tayyari

Theses

Sialic acid (SA) is a general term for a family composed of 43 derivatives of neuraminic acid. Whereas N-acetylneuraminic acid (NANA) is the most commonly occurring sialic acid in human. There has been a great interest in the determination of SA in humans because variations in SA level was linked to different medical conditions and diseases. In particular, serum SA are elevated in several types of cancers. SA also exists in Erythropoietin (EPO), a hormone, which induces the production of red blood cells and hence used in the treatment of anemia.

Although of the great physiological significance of SA …