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Mapping Quantitative Trait Loci In Humans: Some Statistical Contributions., Saurabh Ghosh Dr.

Doctoral Theses

Maty qualitative tralts - such an, milk yield la cows, blood pressure in lumans --are known to be determined primarly, though zot exclusively, by inherited genetic luctora. It ls the of coasklerable impartance to identify chromosontal locations of tho genes that control a quantitative character. Linkage analysis (Ou 1990), which deals with the deduction of linkagn and estimation of recombination fractions among the loci controlling a qualitative/quantitative character and major loci wkoo poertions are knows aprfori, is widely used for localisation of gens. Although statistical methodologies for magplag gemen determining dichotomos qualitative charactes in humans aro well-developed, the demicrant of …