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Moving Target Network Steganography, Tapan Soni
Moving Target Network Steganography, Tapan Soni
Theses and Dissertations
A branch of information hiding that has gained traction in recent years is network steganography. Network steganography uses network protocols are carriers to hide and transmit data. Storage channel network steganography manipulates values in protocol header and data fields and stores covert data inside them. The timing channel modulates the timing of events in the protocol to transfer covert information. Many current storage channel network steganography methods have low bandwidths and they hide covert data directly into the protocol which allows discoverers of the channel to read the confidential information. A new type of storage channel network steganography method is …
Prediction Of Drug-Drug Interaction Potential Using Machine Learning Approaches, Joseph Scavetta
Prediction Of Drug-Drug Interaction Potential Using Machine Learning Approaches, Joseph Scavetta
Theses and Dissertations
Drug discovery is a long, expensive, and complex, yet crucial process for the benefit of society. Selecting potential drug candidates requires an understanding of how well a compound will perform at its task, and more importantly, how safe the compound will act in patients. A key safety insight is understanding a molecule's potential for drug-drug interactions. The metabolism of many drugs is mediated by members of the cytochrome P450 superfamily, notably, the CYP3A4 enzyme. Inhibition of these enzymes can alter the bioavailability of other drugs, potentially increasing their levels to toxic amounts. Four models were developed to predict CYP3A4 inhibition: …