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Does Protein Folding Exhibit Self-Organized Criticality?, Addison Wisthoff

Senior Theses

Proteins are known to fold into tertiary structures that determine their functionality in living organisms. By understanding the general features of this folding process, that are independent of specific proteins, folding can be better understood. Self-organized critical systems exhibit behavior that scales with system size. In this project, I wrote a simulation of a simplistic three-dimensional cubic lattice protein model. The model consisted of only two different types of amino acids, one being hydrophobic and the other hydrophilic, known as the HP model. To identify self-organized criticality in proteins, there must be clear signs of power law behavior in the …