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Mchm (4-Methylcyclohexane Methanol) Influences The Predator-Prey Interaction Between Danio Rerio And Daphnia Magna, Anna C. Wagner
Mchm (4-Methylcyclohexane Methanol) Influences The Predator-Prey Interaction Between Danio Rerio And Daphnia Magna, Anna C. Wagner
Electronic Theses and Dissertations
Chemical contamination alters organism-level traits, such as activity and feeding, that can ultimately affect aquatic trophic interactions. Despite the importance of predator-prey relationships in aquatic communities, chemical toxicity is often tested on single species prior to use. For example, 4-methylcyclohexane methanol (MCHM) used in industrial coal-cleaning enters the environment regularly from low-level contamination during disposal and occasionally in high concentrations following accidental spills, but its effects on fish-zooplankton interactions remain unknown. It was hypothesized MCHM exposure affects zebrafish and D. magna swimming behavior differently when exposed individually or together, and ultimately affects their relationship. Zebrafish and D. magna were exposed …
Assessment Of Short-Term Toxicity Of Titanium Dioxide Nano Fiber (Tdnf) In Sprague Dawley Rats, Daniel A. Hunter
Assessment Of Short-Term Toxicity Of Titanium Dioxide Nano Fiber (Tdnf) In Sprague Dawley Rats, Daniel A. Hunter
Electronic Theses and Dissertations
Nanotechnology is easily becoming one of the fastest growing markets around the globe. Synthetic nanomaterials have many unique chemical and physical properties, mainly due to their huge specific surface area and chemical makeup. Specifically, titanium dioxide (TiO2) nanomaterials have high stability, anticorrosive and photocatalytic properties. These nanomaterials have applications for semiconductor photocatalysis, treatment of water, as a photoactive material in nanocrystalline solar cells, and medicine. However, not much is known about the toxicity of TiO2 in the nanofiber form. The objective of the present study is to investigate the adverse effects associated with acute ingestion of TiO …
Total Synthesis Of Biologically Active Natural And Unnatural Products, Julia Heimberger
Total Synthesis Of Biologically Active Natural And Unnatural Products, Julia Heimberger
Electronic Theses and Dissertations
Herbarin A and B were isolated from the fungal strains of Cladosporium herbarum found in marine sponges Aplysina aerophoba and Callyspongia aerizusa. Total synthesis of Herbarin A and B was achieved by carrying out a multi-step synthesis approach, and the antioxidant properties were evaluated using FRAP assay. Toxicity of these compounds was determined using a zebrafish embryo model. Furthermore, synthesis of C-6 alkyl-azaarene derivatives of nucleosides by Csp3-H bond functionalization were investigated. Effective incorporation of 2-methylazaarene moiety at the C-6 position of the protected inosine nucleoside provided a new class of compounds with anticipated enhanced biological activity.