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- Calcium mobilization (2)
- Camptotheca (2)
- 3T3-L1 adipocyte (1)
- Adipogenesis (1)
- Anti-nociceptive (1)
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- Benzofuran (1)
- Camptothecins (CPTs) (1)
- Cancer (1)
- Canosol (1)
- Chemical induction (1)
- Cycloastragenol (1)
- Cytotoxicity (1)
- Ethnobotany (1)
- Etymology (1)
- Fabaceae (1)
- Happytree (1)
- Induced endogenous autotoxicity (1)
- Medicinal uses (1)
- Pharmaceutical crops (1)
- Phenolics (1)
- Pterocarpus soyauxii (1)
- Radix astragali (1)
- T-pruning (1)
- TRPA1 (1)
- Trichome management (1)
- Triterpenoids (1)
- Wood uses (1)
Articles 1 - 5 of 5
Full-Text Articles in Entire DC Network
Cycloastragenol, A Triterpene Aglycone Derived From Radix Astragali, Suppresses The Accumulation Of Cytoplasmic Lipid Droplet In 3t3-L1 Adipocytes (Abstract), Shifeng Wang, Chenxi Zhai, Qing Liu, Xing Wang, Zhenzhen Ren, Yuxin Zhang, Yanling Zhang, Qinghua Wu, Shengnan Sun, Shiyou Li, Yanjiang Qiao
Cycloastragenol, A Triterpene Aglycone Derived From Radix Astragali, Suppresses The Accumulation Of Cytoplasmic Lipid Droplet In 3t3-L1 Adipocytes (Abstract), Shifeng Wang, Chenxi Zhai, Qing Liu, Xing Wang, Zhenzhen Ren, Yuxin Zhang, Yanling Zhang, Qinghua Wu, Shengnan Sun, Shiyou Li, Yanjiang Qiao
NCPC Publications and Patents
No abstract provided.
Identification Of Natural Compound Carnosol As A Novel Trpa1 Receptor Agonist, Chenxi Zhai, Qing Liu, Yuxin Zhang, Shifeng Wang, Yanling Zhang, Shiyou Li, Yanjiang Qiao
Identification Of Natural Compound Carnosol As A Novel Trpa1 Receptor Agonist, Chenxi Zhai, Qing Liu, Yuxin Zhang, Shifeng Wang, Yanling Zhang, Shiyou Li, Yanjiang Qiao
NCPC Publications and Patents
The transient receptor potential ankyrin 1 (TRPA1) cation channel is one of the well-known targets for pain therapy. Herbal medicine is a rich source for new drugs and potentially useful therapeutic agents. To discover novel natural TRPA1 agonists, compounds isolated from Chinese herbs were screened using a cell-based calcium mobilization assay. Out of the 158 natural compounds derived from traditional Chinese herbal medicines, carnosol was identified as a novel agonist of TRPA1 with an EC50 value of 12.46 µM. And the agonistic effect of carnosol on TRPA1 could be blocked by A-967079, a selective TRPA1 antagonist. Furthermore, the specificity of …
Chemical Constituents From Pterocarpus Soyauxii, Zushang Su, Ping Wang, Wei Yuan, Shiyou Li
Chemical Constituents From Pterocarpus Soyauxii, Zushang Su, Ping Wang, Wei Yuan, Shiyou Li
NCPC Publications and Patents
Three new benzofurans (1-3) and one new isoflavan (4), pteroyanin G, H, I and J, together with 21 known compounds, were isolated from the heartwood of Pterocarpus soyauxii. Their structures were determined by the NMR and MS spectral data in comparison with literature data. Compounds (1-25) did not show cytotoxicity against three human cancer cell lines, A549, Panc-28, and HCT-116 (Gl50 > 50 μM)
Ethnobotany Of Camptotheca Decaisne: New Discoveries Of Old Medicinal Uses, Shiyou Li, Wanli Zhang
Ethnobotany Of Camptotheca Decaisne: New Discoveries Of Old Medicinal Uses, Shiyou Li, Wanli Zhang
NCPC Publications and Patents
Camptotheca trees had been used as fuelwood and an ornamental species in its native China. There were no reports on medicinal uses of Camptotheca in China and thus it was believed the trees had no medicinal before its antitumor activity discovered in 1957. We conducted national surveys of Camptotheca in China from 1994 to 1999. We found that Camptotheca acuminate is commonly known as happytree (xi shu) because the trees can be used as folk medicine to cure stubborn phlegm as well as other diseases, thus making patients “happy”. There are three local names to refer the uses of C. …
Trichome Management To Enhance Camptothecins In Camptotheca Decaisne, Shiyou Li, Zhizhen Zhang, Ping Wang, Wei Yuan
Trichome Management To Enhance Camptothecins In Camptotheca Decaisne, Shiyou Li, Zhizhen Zhang, Ping Wang, Wei Yuan
NCPC Publications and Patents
Inducible chemical defenses of plants have received much attention in the last three decades, and these defenses often involve trichomes. It is known that some plant secondary metabolites may accumulate in trichomes which can protect plants from damage by herbivores. However, studies on plant trichomes are largely limited to some major vegetable or cash crops and model species with large glandular trichomes (e.g., Nictotiana and Arabidopsis). In fact, the existing studies on the effect of damage (pruning or defoliation) on trichome density or chemical production in plants are partial and even contradictory. Management strategies to maximize chemical induction in …