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Rapid Effects Of 25-Hydroxyvitamin D3 On Calcium Uptake In Isolated Chick Enterocytes, Ruta Phadnis

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

25-Hydroxyvitamin D₃[25(OH)D₃] is a metabolite of vitamin D₃ that has long been considered to be an inactive precursor of the hormonally active metabolite 1,25- dihydroxyvitamin D₃[l,25(OH)₂D₃]; consequently very few studies have addressed the potential biological activity of 25(OH)₂D₃. However, it is known that 100 nM 25(OH)₂D₃ increases calcium transport in the perfused duodenal loop of the chicken to 200% of controls within 20 minutes. The hypothesis of the current study is that 25(OH)₂D₃ may be a hormonally active metabolite …

Vitamin K As A Prophylaxis In The Infant, Michelle Whipple

Undergraduate Honors Capstone Projects

Since the mid-1960's, all infants in the US have received intramuscular vitamin K (IMVK) as a prophylactic measure against hemorrhagic disease of the newborn (HDN). Because the human race has obviously survived for so many years without this medical intervention, there is some question concerning the universal necessity of this practice.

Infants are born with comparatively low levels of vitamin K, a compound vital for the carboxylation of serum clotting factors. In the absence of adequately carboxylated clotting proteins, infants are at risk for developing HDN. This condition can cause severe complications, including mental retardation and death. IMVK significantly reduces …

The Effects Of Alternative-Site Blood Glucose Monitoring On Testing Frequency, Pain Rating, And Glycosylated Hemoglobin, Nancy Bennion

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

A crossover design study was conducted to determine if reducing pain, by using alternative sites off the finger tip, would increase testing frequency and improve clinical outcome as measured by glycosylated hemoglobin. Subjects with type 1 and type 2 diabetes tested with the FreeStyle alternative-site meter (group 1) or tested with their original meter (group 2). After 3 months the subjects used the alternate meter. Testing frequency and blood glucose concentrations were recorded for the month before the study began and monthly thereafter. Glycosylated hemoglobin was tested initially, at the crossover point, and at study conclusion. Insulin users increased testing …

Determining The Influence Of The Extracellular Proteinase From Brevibacterium Linens On The Metabolism Of Lactococcus Lactis Spp. Lactis Using Functional Genomics, Yi Xie

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Since the catabolism of amino acids in cheese results in the formation of most volatile flavor compounds, a proper intracellular pool of amino acids must be established in order to produce a desirable flavor production in cheese. Generation of this pool of amino acids requires complex interactions among casein and its derivatives, proteolytic enzymes, and transport systems in the associated bacteria, including lactococci. In this project, we hypothesized that casein hydrolysis by the extracellular proteinases of Brevibacterium linens BL2 modulates the expression profile of proteolytic related genes in Lactococcus lactis spp. lactis IL1403.

In order to monitor the …