Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Entire DC Network
Mitochondrial Fragmentation Is Involved In Methamphetamine-Induced Cell Death In Rat Hippocampal Neural Progenitor Cells., Changhai Tian, L. Charles Murrin, Jialin C. Zheng
Mitochondrial Fragmentation Is Involved In Methamphetamine-Induced Cell Death In Rat Hippocampal Neural Progenitor Cells., Changhai Tian, L. Charles Murrin, Jialin C. Zheng
Journal Articles: Pharmacology & Experimental Neuroscience
Methamphetamine (METH) induces neurodegeneration through damage and apoptosis of dopaminergic nerve terminals and striatal cells, presumably via cross-talk between the endoplasmic reticulum and mitochondria-dependent death cascades. However, the effects of METH on neural progenitor cells (NPC), an important reservoir for replacing neurons and glia during development and injury, remain elusive. Using a rat hippocampal NPC (rhNPC) culture, we characterized the METH-induced mitochondrial fragmentation, apoptosis, and its related signaling mechanism through immunocytochemistry, flow cytometry, and Western blotting. We observed that METH induced rhNPC mitochondrial fragmentation, apoptosis, and inhibited cell proliferation. The mitochondrial fission protein dynamin-related protein 1 (Drp1) and reactive oxygen …
Persistencia De Anticuerpos Maternales Contra El Virus De La Peste Porcina Clásica En Lechones Nacidos De Marranas En Granjas Con Diferentes Estrategias De Vacunación, Katherine J. Portilla, Albert Manchego S., Hermelinda G. Rivera, Mariluz Araínga, Marcy Ramierz V.
Persistencia De Anticuerpos Maternales Contra El Virus De La Peste Porcina Clásica En Lechones Nacidos De Marranas En Granjas Con Diferentes Estrategias De Vacunación, Katherine J. Portilla, Albert Manchego S., Hermelinda G. Rivera, Mariluz Araínga, Marcy Ramierz V.
Journal Articles: Pharmacology & Experimental Neuroscience
In the study evaluated was the persistence of maternal antibodies levels Classical Swine Fever Against the virus (CSFV) in Vaccinated piglets born from sows from two farms (A and B) With different strategies against CSFV vaccination. In farm A sows were vaccinated at 90 days of gestation and in farm B at 18 - 21 days postpartum. Serum samples were collected from piglets of both farms, at first (n=15), third (n=15), fifth (n=15) and seventh (n=15) weeks of age, and from 15 sows from each farm A for detection of antibodies against CSFV by the indirect ELISA test. All piglets …