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Perceived Factors Of Intimate Partner Violence On Women Diagnosed With Post-Traumatic Stress Disorder, Angela M. Halcovich
Perceived Factors Of Intimate Partner Violence On Women Diagnosed With Post-Traumatic Stress Disorder, Angela M. Halcovich
Walden Dissertations and Doctoral Studies
Post-Traumatic Stress Disorder (PTSD) is a prevalent diagnosis, and many human and social services professionals strive to understand its components, to ensure that they serve the population properly. However, little is known about how PTSD may influence women’s vulnerabilities to and future experiences of intimate partner violence (IPV). Emphasizing relationship coaching, which provides tools to foster healthy relationships, within the therapeutic curricula on rehabilitation for women with PTSD may result in reduced chances to experience IPV as women integrate back into their everyday life after being diagnosed and treated for PTSD. The purpose of this generic qualitative study was to …
Perceived Factors Of Intimate Partner Violence On Women Diagnosed With Post-Traumatic Stress Disorder, Angela M. Halcovich
Perceived Factors Of Intimate Partner Violence On Women Diagnosed With Post-Traumatic Stress Disorder, Angela M. Halcovich
Walden Dissertations and Doctoral Studies
Post-Traumatic Stress Disorder (PTSD) is a prevalent diagnosis, and many human and social services professionals strive to understand its components, to ensure that they serve the population properly. However, little is known about how PTSD may influence women’s vulnerabilities to and future experiences of intimate partner violence (IPV). Emphasizing relationship coaching, which provides tools to foster healthy relationships, within the therapeutic curricula on rehabilitation for women with PTSD may result in reduced chances to experience IPV as women integrate back into their everyday life after being diagnosed and treated for PTSD. The purpose of this generic qualitative study was to …
Neural Correlates And Neuroanatomy Of Juvenile And Adult Contextual Fear Memory Retention, Natalie Odynocki
Neural Correlates And Neuroanatomy Of Juvenile And Adult Contextual Fear Memory Retention, Natalie Odynocki
Legacy Theses & Dissertations (2009 - 2024)
AbstractFear is an evolutionarily conserved mechanism that allows an organism to discern potential harm and act accordingly by engaging in defensive behaviors. While fear is an adaptive response, dysregulation of fear by means of a traumatic event can lead to psychiatric conditions such as post-traumatic stress disorder (PTSD). Animal research using rodents in Pavlovian context fear conditioning experiments allows for the ability to study the underlying neural circuitry of threat-appropriate and aberrant fear learning and memory that may contribute to PTSD. However, despite reports that women are more than two times more likely to develop PTSD compared to men, the …
Effect Of Neighborhood Socioeconomic Disadvantage On Brain Functional Connectivity And Structural Properties In Trauma-Exposed Adults, Elisabeth Kathleen Webb
Effect Of Neighborhood Socioeconomic Disadvantage On Brain Functional Connectivity And Structural Properties In Trauma-Exposed Adults, Elisabeth Kathleen Webb
Theses and Dissertations
Though there has been substantial progress towards understanding brain-behavior relationships and characterizing the neurobiology of psychiatric disorders, research has not translated as expected into novel prevention and treatment of mental health conditions. One limitation may be the emphasis on individual-level variables (e.g., income) and omission of relevant area-level factors (e.g., neighborhood socioeconomic disadvantage). Recently, attention has been directed towards identifying the biological mechanisms by which neighborhoods impact mental health. The chronic stress associated with living in a disadvantaged neighborhood promotes a cascade of maladaptive events, which in turn impact brain structure and functioning. The processes affected by chronic neighborhood stressors …
Facing Fears When Fearing Faces: Binocular Rivalry Perceptual Alternation And Approach-Avoidance In College-Aged Women With Autistic Traits And A History Of Adverse Experiences, Sarah Kamhout
Undergraduate Honors Theses
Women with Autism Spectrum Conditions (ASCs) may be more likely to experience symptoms of trauma exposure due to greater likelihood of facing adverse childhood experiences (ACEs). In order to gain a better understanding of the neural mechanisms involved with ASC and PTSD in women who experience difficulty with social interactions, I examined the ability of two vision tasks-- Binocular Rivalry Perceptual Alternation (BR) and Visual Approach/Avoidance by the Self Task (VAAST)-- to predict symptoms of both conditions as well as differentiate between them. I also examined differences in response to neutral or emotional (angry or fearful) faces under both paradigms. …
Neural Correlates Underlying The Interactions Between Anxiety And Cannabis Use In Predicting Motor Response Inhibition, Richard Ward
Neural Correlates Underlying The Interactions Between Anxiety And Cannabis Use In Predicting Motor Response Inhibition, Richard Ward
Theses and Dissertations
The ability to effectively withhold an inappropriate response is a critical feature of cognitive control. Prior research indicates alterations in neural processes required for motor response inhibition in anxious individuals, including those with posttraumatic stress disorder (PTSD), and those who engage in regular cannabis use. However, thus far most research has examined how anxiety-related symptoms and cannabis use influence response inhibition in isolation of one another. The current study examined the interactions between anxious symptomology and recent cannabis use in a sample that recently experienced a traumatic event using functional magnetic resonance imaging (fMRI) during the completion of a Stop-Signal …
Data-Driven Approach To Dynamic Resting State Functional Connectivity In Post-Traumatic Stress Disorder, Carissa Weis
Data-Driven Approach To Dynamic Resting State Functional Connectivity In Post-Traumatic Stress Disorder, Carissa Weis
Theses and Dissertations
Posttraumatic stress disorder (PTSD) is a heterogenous psychological disorder that may result from exposure to a traumatic event. Using functional magnetic resonance imaging (fMRI), symptoms of PTSD have been associated with aberrations in brain networks that emerge in the absence of a given cognitive demand or task, called resting state networks. Most previous research in resting state networks and PTSD has focused on aberrations in the static functional connectivity among specific regions of interest (ROI) in the brain and within canonical networks constrained by a priori hypotheses. However, dynamic fMRI, an approach that examines changes in brain network characteristics over …
Individual Differences In Ultrasonic Vocalizations And Freezing Behavior During Fear Learning And Extinction In Female Rats, Iris M. Sakamoto
Individual Differences In Ultrasonic Vocalizations And Freezing Behavior During Fear Learning And Extinction In Female Rats, Iris M. Sakamoto
Senior Theses
Although many people experience traumatic events, only 10%-20% go on to develop post- traumatic stress disorder (PTSD). Women are particularly susceptible, with a prevalence rate double that of men, even when controlling for type of trauma exposure. This disparity suggests the existence of distinct neurobiological processes, particularly related to sex, that predispose some individuals to be more resistant to extinguishing learned fear. Similar differences exist in rodent fear conditioning and extinction, though female rodents are considerably understudied. We hypothesized that female rodents would exhibit individual differences in fear extinction similar to those that we have observed previously in males. The …
White Matter Integrity In Individuals At-Risk For Ptsd Development: A Longitudinal Investigation, Carissa Weis
White Matter Integrity In Individuals At-Risk For Ptsd Development: A Longitudinal Investigation, Carissa Weis
Theses and Dissertations
Trauma exposure is prevalent and while most are resilient, some go on to develop post-traumatic stress disorder (PTSD)—an anxiety-related disorder that results from traumatic experience. The brain changes that result from traumatic experience and PTSD are not well understood. Further, little is known about what distinguishes those who are resilient after trauma from those at risk for developing PTSD. Previous work indicates white matter integrity may be a useful biomarker in predicting PTSD and researchers have found changes in the integrity of three white matter tracts—the cingulum bundle, corpus callosum (CC), and uncinate fasciculus (UF)—in the aftermath of trauma. However, …
White Matter Integrity In Individuals At-Risk For Ptsd Development: A Longitudinal Investigation, Carissa Weis
White Matter Integrity In Individuals At-Risk For Ptsd Development: A Longitudinal Investigation, Carissa Weis
Theses and Dissertations
Trauma exposure is prevalent and while most are resilient, some go on to develop post-traumatic stress disorder (PTSD)—an anxiety-related disorder that results from traumatic experience. The brain changes that result from traumatic experience and PTSD are not well understood. Further, little is known about what distinguishes those who are resilient after trauma from those at risk for developing PTSD. Previous work indicates white matter integrity may be a useful biomarker in predicting PTSD and researchers have found changes in the integrity of three white matter tracts—the cingulum bundle, corpus callosum (CC), and uncinate fasciculus (UF)—in the aftermath of trauma. However, …
Curcumin Inhibits The Ikk:Nf-Kappa B Pathway In Neural Fear Circuits, Miguel A. Briones
Curcumin Inhibits The Ikk:Nf-Kappa B Pathway In Neural Fear Circuits, Miguel A. Briones
Dissertations, Theses, and Capstone Projects
The study of how the brain acquires fearful memories has attracted considerable experimental attention, due in part to the promise of discovering novel therapeutic approaches for psychiatric disorders that are characterized by unusually strong and persistent traumatic memories. In recent years, extensive research has focused on studying the neural and molecular mechanisms by which fear memories are acquired, stored, and retrieved in the brain. Once acquired, fear memories may be attenuated using one of 2 procedures: 1) fear extinction, which involves repeated presentation of the fear-arousing stimulus in the absence of an aversive consequence, or 2) interference with the reconsolidation …
Prefrontal Cortex Dopamine Transmission Regulates Emotional Memory Processing And Morphine Reward Salience: Implications For Post-Traumatic Stress Disorder And Addiction Comorbidity, Jing Jing Li
Electronic Thesis and Dissertation Repository
Post-Traumatic Stress Disorder (PTSD) and addiction are strongly comorbid. However, the underlying neural mechanisms by which traumatic memory recall may increase addiction liability are poorly understood. The inability to suppress memory recall related to either stressful or rewarding, drug-related experiences may be an underlying neuropsychological feature capable of triggering both PTSD or addiction-related behaviours. Our previous research has shown that transmission through dopamine (DA) D4 and D1 receptor subtypes (D4R, D1R) within the prefrontal cortex (PFC) strongly modulates emotional memory acquisition and recall (Lauzon et al., 2009). Using olfactory fear conditioning and morphine conditioned …
The Effect Of Ethanol Consumption And Stress On Brain Derived Neurotrophic Factor And Tropomyosin Receptor Kinase B Expression., Katie Marie Masters
The Effect Of Ethanol Consumption And Stress On Brain Derived Neurotrophic Factor And Tropomyosin Receptor Kinase B Expression., Katie Marie Masters
Chancellor’s Honors Program Projects
No abstract provided.
Dopamine D1 Receptor Activity In The Basolateral Amygdala Is Important For Mediating Fear, Reward And Safety Discrimination Learning, Ka Ho Ng
Open Access Theses
Post traumatic stress disorder (PTSD) patients frequently show impairment in safety learning (Jovanovic, Kazama, Bachevalier, & Davis, 2012). Since the amygdala is known to be critical for emotional processing(Wassum & Izquierdo, 2015) and dopamine signaling in the amygdala is important for mediating both fear and reward learning, current experiments examined the role of dopamine signaling in the BLA in mediating both safety learning and reward seeking. We manipulated dopamine D1 receptor activity with a D1 receptor agonist (SKF 38393) or D1 receptor antagonist (SCH23390) either systemically or infused directly into the BLA 20 minutes prior to training rats in a …
Ultrasonic Vocalizations As A Predictor Of Resilience To Intermittent Swim Stress-Induced Anxiety: An Investigation Of Re-Exposure Effects, Yandan Wang, Robert C. Drugan, Nathaniel Stafford
Ultrasonic Vocalizations As A Predictor Of Resilience To Intermittent Swim Stress-Induced Anxiety: An Investigation Of Re-Exposure Effects, Yandan Wang, Robert C. Drugan, Nathaniel Stafford
Honors Theses and Capstones
No abstract provided.