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Sex- And Age-Associated Effects On The Retrosplenial Cortex Following Trace Fear Learning, Hanna Yousuf

Theses and Dissertations

The rodent granular retrosplenial cortex (gRSC) forms reciprocal connections with the thalamus and hippocampus (Van Groen and Wyss, 1990, 1992; Sugar et al., 2011). The gRSC is well-positioned to coordinate information between higher-order brain structures to support complex forms of memory such as associative trace fear memories (Kwapis et al., 2014, 2015). Further, sex differences in fear learning and mechanisms underlying fear memories are observed in many of the brain regions implicated in trace fear learning such as the hippocampus, amygdala, and mPFC (Maren et al., 1994; Dalla et al., 2009; Gresack et al., 2009; Blume et al., 2017; Keiser …