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Difference In The Inhibitory Effects Of Violacein On Various Yeast Isolate Strains From The Hudson Valley Region, Lilah Dorothy Blaker
Difference In The Inhibitory Effects Of Violacein On Various Yeast Isolate Strains From The Hudson Valley Region, Lilah Dorothy Blaker
Senior Projects Spring 2023
Violacein is a purple pigmented compound produced by numerous bacterial species including Janthinobacterium lividum. Studies into violacein have found it to have a multitude of medicinal properties, from antifungal, antibiotic, to antitumor activity. Research has shown that violacein significantly inhibits both tumor and fungal growth and it has been shown to have higher cyotoxicity in pathogenic or cancerous cells than in healthy ones, giving it great potential as for use as a pharmaceutical drug in humans, alongside the fact that as a bacterial compound it’s easier and faster to produce than some other drugs. Violacein has also been shown to …
Diversification Of Ergot Alkaloid Biosynthesis In Natural And Engineered Fungi, Kyle Austin Davis
Diversification Of Ergot Alkaloid Biosynthesis In Natural And Engineered Fungi, Kyle Austin Davis
Graduate Theses, Dissertations, and Problem Reports
Ergot alkaloids are a complex family of tryptophan-derived mycotoxins produced by a diverse range of fungi that occupy a wide variety of ecological niches including soil saprotrophs, plant endophytes, pathogens of plants or insects, and opportunistic pathogens of humans and other mammals. Ergot alkaloids are a similarly diverse family of chemicals that elicit a variety of pharmacological activities in animals due to their resemblance to neurotransmitters and high binding affinity for neurological receptors, including those that bind adrenaline, dopamine, and 5-hydroxytryptamine receptors. These structural similarities allow us to create medicines aimed at treating a range of neurological diseases and disorders …