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Retracted Publications In Otolaryngology-Head And Neck Surgery: What Mistakes Are Being Made?, Hannaan S Choudhry, Sugosh M Anur, Hassan S Choudhry, Emily M Kokush, Aman M Patel, Christina H Fang Jan 2024

Retracted Publications In Otolaryngology-Head And Neck Surgery: What Mistakes Are Being Made?, Hannaan S Choudhry, Sugosh M Anur, Hassan S Choudhry, Emily M Kokush, Aman M Patel, Christina H Fang

Otolaryngology (ENT) Resident Research

OBJECTIVES: Retraction of publications is critical to maintaining scientific integrity, yet there is a lack of research on its occurrence in Otolaryngology. This study investigates characteristics, trends, and reasons for retraction of publications in otolaryngology journals.

STUDY DESIGN: Bibliometric analysis.

SETTING: PubMed, Scopus, Web of Science.

METHODS: A PubMed search for publications retracted during 1990 to 2022 from the top 60 journals with the subject "Otorhinolaryngology" using Scopus' CiteScore was performed. Publications were excluded if they were not in English, had missing information or did not have available abstracts or full-text. Publication and retraction dates, journal, country of origin, citation …


Improving Pubmed For The Novice At The Expense Of The Expert: Surveying Librarians 3 Years Post-New Pubmed, Tim Kenny Mls, Heather Kemp Mlis May 2023

Improving Pubmed For The Novice At The Expense Of The Expert: Surveying Librarians 3 Years Post-New Pubmed, Tim Kenny Mls, Heather Kemp Mlis

MaineHealth Maine Medical Center

Background: In 2019 PubMed, the publically accessible search interface for the MEDLINE database underwent a user interface update and overhaul. MEDLINE is the primary component of PubMed, a literature database developed and maintained by the NLM National Center for Biotechnology Information (NCBI)” (National Library of Medicine, 2022).

Methods: Using a brief web-based survey, comprised of both closed-ended and open-ended questions, health science library professionals provided feedback on the new PubMed.


Peer Reviewed Evaluation Of Registered End-Points Of Randomised Trials (The Pre-Report Study): A Stepped Wedge, Cluster-Randomised Trial., Christopher Jones, Amanda Adams, Benjamin S Misemer, Mark A Weaver, Sara Schroter, Hayat Khan, Benyamin Margolis, David L Schriger, Timothy F Platts-Mills Sep 2022

Peer Reviewed Evaluation Of Registered End-Points Of Randomised Trials (The Pre-Report Study): A Stepped Wedge, Cluster-Randomised Trial., Christopher Jones, Amanda Adams, Benjamin S Misemer, Mark A Weaver, Sara Schroter, Hayat Khan, Benyamin Margolis, David L Schriger, Timothy F Platts-Mills

Cooper Medical School of Rowan University Departmental Research

OBJECTIVE: To test whether providing relevant clinical trial registry information to peer reviewers evaluating trial manuscripts decreases discrepancies between registered and published trial outcomes.

DESIGN: Stepped wedge, cluster-randomised trial, with clusters comprised of eligible manuscripts submitted to each participating journal between 1 November 2018 and 31 October 2019.

SETTING: Thirteen medical journals.

PARTICIPANTS: Manuscripts were eligible for inclusion if they were submitted to a participating journal during the study period, presented results from the primary analysis of a clinical trial, and were peer reviewed.

INTERVENTIONS: During the control phase, there were no changes to pre-existing peer review practices. After journals …


From Start To Finish: Examining Factors Associated With Higher Likelihood Of Publication Among Abstracts Presented At An International Infectious Diseases Scientific Meeting, Asia J. Johnson, Christopher M. Bland, Chengwen Teng, Lily Zheng, J Colin Hungerpiller, Morgan Easterling, Sarah Arnold, Madeline Dean, Carrington Royals, P. Brandon Bookstaver Aug 2022

From Start To Finish: Examining Factors Associated With Higher Likelihood Of Publication Among Abstracts Presented At An International Infectious Diseases Scientific Meeting, Asia J. Johnson, Christopher M. Bland, Chengwen Teng, Lily Zheng, J Colin Hungerpiller, Morgan Easterling, Sarah Arnold, Madeline Dean, Carrington Royals, P. Brandon Bookstaver

Faculty Publications

Background The landscape of infectious diseases research by interprofessional teams continues to change in both scope and engagement. Limited information exists regarding publication metrics and factors associated with publication of abstracts presented at professional infectious diseases meetings.

Methods This was a retrospective, observational study evaluating abstracts presented at IDWeek in 2017 and 2018. The primary endpoint was the proportion of abstracts that were subsequently published in peer-reviewed journals. Factors associated with publication were evaluated, and a description of publication metrics was reported.

Results Of the 887 abstracts analyzed from the IDWeek meetings, 236 (26.6%) were published. Significantly more abstracts were …


Gender Parity In Authorship Of Published Randomized Clinical Trials In Stroke Neurology From 2000 To 2021., Noor F Shaik, Ali A Saherwala, Diana L Tzeng Mar 2022

Gender Parity In Authorship Of Published Randomized Clinical Trials In Stroke Neurology From 2000 To 2021., Noor F Shaik, Ali A Saherwala, Diana L Tzeng

Department of Neurology Faculty Papers

Gender parity is a crucial goal in clinical medicine so that women have equal access and representation. Although approximately half (46%) of US neurology residents and fellows are female, proportions of female assistant, associate, and full professors are 49%, 41%, and 23%, respectively. This has far-reaching effects, from clinical publications to invited speakerships.Although a study noted increasing trends in female authorship in high-impact neurology journals the current literature lacks evidence on a more informative benchmark—first and last authorship in randomized clinical trials (RCTs), which is typically considered for career advancement. This study assessed annual proportions and trends of female first …


Health Insurance Coverage Disruptions And Cancer Care And Outcomes: Systematic Review Of Published Research, K Robin Yabroff, Katherine Reeder-Hayes, Jingxuan Zhao, Michael T Halpern, Ana Maria Lopez, Leon Bernal-Mizrachi, Anderson B Collier, Joan Neuner, Jonathan Phillips, William Blackstock, Manali Patel Jul 2020

Health Insurance Coverage Disruptions And Cancer Care And Outcomes: Systematic Review Of Published Research, K Robin Yabroff, Katherine Reeder-Hayes, Jingxuan Zhao, Michael T Halpern, Ana Maria Lopez, Leon Bernal-Mizrachi, Anderson B Collier, Joan Neuner, Jonathan Phillips, William Blackstock, Manali Patel

Kimmel Cancer Center Faculty Papers

BACKGROUND: Lack of health insurance coverage is associated with poor access and receipt of cancer care and survival in the United States. Disruptions in coverage are common among low-income populations, but little is known about associations of disruptions with cancer care, including prevention, screening, and treatment, as well as outcomes of stage at diagnosis and survival.

METHODS: We conducted a systematic review of studies of health insurance coverage disruptions and cancer care and outcomes published between 1980 and 2019. We used the PubMed, EMBASE, Scopus, and CINAHL databases and identified 29 observational studies. Study characteristics and key findings were abstracted …


Manuscript Writing And Publication Workshop: An Invoking Pilot Study On Enhancing Cognitive Research Capabilities In Health Sciences Institutes Of Pakistan, Mehwish Hussain, Rehana Rehman, Mukhtiar Baig Jun 2020

Manuscript Writing And Publication Workshop: An Invoking Pilot Study On Enhancing Cognitive Research Capabilities In Health Sciences Institutes Of Pakistan, Mehwish Hussain, Rehana Rehman, Mukhtiar Baig

Department of Biological & Biomedical Sciences

Background: With an upsurge in research in developing countries, researchers from allied sciences need to augment their skills for disseminating research work worldwide. Training workshop is one of the quick interventions which can enhance writing skills and ease research publication.
Objective: We designed this research to explore the perception of the faculty of different higher education institutes (HEIs) regarding manuscript writing and to assess the impact of these workshops in the improvement of cognitive capabilities of preliminary researchers in Pakistan.
Methodology: We conducted workshops in HEIs of Sindh, Pakistan. Contents of the workshop covered algorithm of writing manuscript and related …


When Will I Get My Paper Back? A Replication Study Of Publication Timelines For Health Professions Education Research., Lauren A Maggio, William E Bynum, Deanna N Schreiber-Gregory, Steven J Durning, Anthony R. Artino Jun 2020

When Will I Get My Paper Back? A Replication Study Of Publication Timelines For Health Professions Education Research., Lauren A Maggio, William E Bynum, Deanna N Schreiber-Gregory, Steven J Durning, Anthony R. Artino

Health, Human Function, and Rehabilitation Sciences Faculty Publications

INTRODUCTION: Biomedical researchers have lamented the lengthy timelines from manuscript submission to publication and highlighted potential detrimental effects on scientific progress and scientists' careers. In 2015, Himmelstein identified the mean time from manuscript submission to acceptance in biomedicine as approximately 100 days. The length of publication timelines in health professions education (HPE) is currently unknown.

METHODS: This study replicates Himmelstein's work with a sample of 14 HPE journals published between 2008-2018. Using PubMed, 19,182 article citations were retrieved. Open metadata for each were downloaded, including the date the article was received by the journal, date the authors resubmitted revisions, date …


The National Framework For Health And Wellness: (Re)Framing The Work Of Cooperative Extension For The Next Century, David Buys, Sonja Koukel May 2018

The National Framework For Health And Wellness: (Re)Framing The Work Of Cooperative Extension For The Next Century, David Buys, Sonja Koukel

Journal of Human Sciences and Extension

Cooperative Extension is at a crossroads and has increasing opportunities to articulate its existing role and future growth in impacting the health and wellness of the individuals and communities it serves. This is important because the health outcomes in the U.S. are poorer than any other developed nation, health expenditures are high, challenges with navigating the health system are immense, and opportunities to intervene and remove barriers to improving the nation’s health and wellness abound. This article provides suggestions as a follow-up to the reports featured in this special issue of the Journal of Human Sciences and Extension from the …


A Bibliometric Analysis Of Peer-Reviewed Journal Publications By British Occupational Therapy Authors, Ted Brown, Yuh-Shan Ho, Sharon A. Gutman Jan 2018

A Bibliometric Analysis Of Peer-Reviewed Journal Publications By British Occupational Therapy Authors, Ted Brown, Yuh-Shan Ho, Sharon A. Gutman

The Open Journal of Occupational Therapy

Background: A bibliometric analysis was completed of the peer-reviewed literature from 1991 to 2015 written by British occupational therapy authors that was indexed in the Science Citation Index-Expanded (SCI-Expanded) or Social Sciences Citation Index (SSCI) databases.

Methods: “Occupational therapy” and “occupational therapist” were used as keywords to search journal articles’ publication title, abstract, author details, keywords, and KeyWords Plus. One of the authors had to be identified as a qualified occupational therapist with a British affiliation.

Results: From 1991 to 2015, 680 journal articles were published by British occupational therapy authors. The top three journals in which authors published …


Data Publication With The Structural Biology Data Grid Supports Live Analysis, Peter A. Meyer, Stephanie Socias, Jason Key, Elizabeth Ransey, Emily C. Tjon, Alejandro Buschiazzo, Ming Lei, Chris Botka, James Withrow, David Neau, Kanagalaghatta Rajashankar, Karen S. Anderson, Richard H. Baxter, Stephen C. Blacklow, Titus J. Boggon, Alexandre M. J. J. Bonvin, Dominika Borek, Tom J. Brett, Amedeo Caflisch, Chung-I Chang, Walter J. Chazin, Kevin D. Corbett, Michael S. Cosgrove, Sean Crosson, Sirano Dhe-Paganon, Enrico Di Cera, Catherine L. Drennan, Michael J. Eck, Brandt F. Eichman, Qing R. Fan, Oleg V. Tsodikov Mar 2016

Data Publication With The Structural Biology Data Grid Supports Live Analysis, Peter A. Meyer, Stephanie Socias, Jason Key, Elizabeth Ransey, Emily C. Tjon, Alejandro Buschiazzo, Ming Lei, Chris Botka, James Withrow, David Neau, Kanagalaghatta Rajashankar, Karen S. Anderson, Richard H. Baxter, Stephen C. Blacklow, Titus J. Boggon, Alexandre M. J. J. Bonvin, Dominika Borek, Tom J. Brett, Amedeo Caflisch, Chung-I Chang, Walter J. Chazin, Kevin D. Corbett, Michael S. Cosgrove, Sean Crosson, Sirano Dhe-Paganon, Enrico Di Cera, Catherine L. Drennan, Michael J. Eck, Brandt F. Eichman, Qing R. Fan, Oleg V. Tsodikov

Pharmaceutical Sciences Faculty Publications

Access to experimental X-ray diffraction image data is fundamental for validation and reproduction of macromolecular models and indispensable for development of structural biology processing methods. Here, we established a diffraction data publication and dissemination system, Structural Biology Data Grid (SBDG; data.sbgrid.org), to preserve primary experimental data sets that support scientific publications. Data sets are accessible to researchers through a community driven data grid, which facilitates global data access. Our analysis of a pilot collection of crystallographic data sets demonstrates that the information archived by SBDG is sufficient to reprocess data to statistics that meet or exceed the quality of the …


Normalizing Rejection, Vicki S. Conn, Julie Zerwic, Urmeka Jefferson, Cindy M. Anderson, Cheryl M. Killion, Carol E. Smith, Marlene Z. Cohen, Nancy Fahrenwald, Linda Herrick, Robert V. Topp, Lazelle E. Benefield, Julio Loya Feb 2016

Normalizing Rejection, Vicki S. Conn, Julie Zerwic, Urmeka Jefferson, Cindy M. Anderson, Cheryl M. Killion, Carol E. Smith, Marlene Z. Cohen, Nancy Fahrenwald, Linda Herrick, Robert V. Topp, Lazelle E. Benefield, Julio Loya

College of Nursing Faculty Research and Publications

Getting turned down for grant funding or having a manuscript rejected is an uncomfortable but not unusual occurrence during the course of a nurse researcher’s professional life. Rejection can evoke an emotional response akin to the grieving process that can slow or even undermine productivity. Only by “normalizing” rejection, that is, by accepting it as an integral part of the scientific process, can researchers more quickly overcome negative emotions and instead use rejection to refine and advance their scientific programs. This article provides practical advice for coming to emotional terms with rejection and delineates methods for working constructively to address …


Transforming The Managerial Class: Binary And Dialectical Thinking In Counseling, Thomas Harrison, Troyann I. Gentile, Terianne Harrison Oct 2015

Transforming The Managerial Class: Binary And Dialectical Thinking In Counseling, Thomas Harrison, Troyann I. Gentile, Terianne Harrison

Troyann I. Gentile

Many counselor conceptualizations of client issues as well as interventions with clients are replete with binary thinking. The subtle result can be a type of management of clients which serves to both create change on some levels and to thwart change on other levels. Clearly, this is in direct opposition to the fundamental tenets of professional counseling. Dialectical thought is defined as the "developmental movement through forms." Dialectical thought is a type of "both/and" thinking that includes binary thought as a subset of advanced systems theory. In essence, dialectical thought puts motion into the binary thought process. This article will …


The War Within: One Soldier's Experience, Several Clinician's Perspectives, Laura M. Schmuldt, Troyann I. Gentile, Jason S. Bluemlein, John C. Fitch Iii, William R. Sterner Oct 2015

The War Within: One Soldier's Experience, Several Clinician's Perspectives, Laura M. Schmuldt, Troyann I. Gentile, Jason S. Bluemlein, John C. Fitch Iii, William R. Sterner

Troyann I. Gentile

Soldiers returning from deployment are presenting with a plethora of serious mental health challenges, including depression, anxiety, post-traumatic stress disorder, sleep disturbances, and substance abuse issues. This paper will describe the journey of one soldier following his deployment to Iraq and the difficulties he faced during reintegration. Clinicians representing five approaches – dialectical behavior therapy (DBT), eye movement desensitization and reprocessing (EMDR), group systems theory, and motivational interviewing (MI) will provide perspectives on the development of traumatic response symptomology, as well as suggestions for understanding and treating the soldier profiled in the case study.


Video Applications For Online Counseling: Design And Practice, Leping Liu, Troyann I. Gentile Oct 2015

Video Applications For Online Counseling: Design And Practice, Leping Liu, Troyann I. Gentile

Troyann I. Gentile

Online counseling has been one important portion in our counseling skill training courses. In online counseling, video applications (such as video-conferences, storytelling, interactive information materials, screen-capture video, and counseling video session evaluation) are used for client assessment, online communications, counseling education and evaluation. This paper will present the analysis, design, implementation, and evaluation of integrating these applications into online counseling. Methods, procedures, activities, and issues will be described.


Counselor Education Beyond Our Borders: Promoting Mental Health Counseling In Romania Through A Service–Learning Project, Troyann I. Gentile, Laura M. Schmuldt, Barry Stephens Oct 2015

Counselor Education Beyond Our Borders: Promoting Mental Health Counseling In Romania Through A Service–Learning Project, Troyann I. Gentile, Laura M. Schmuldt, Barry Stephens

Troyann I. Gentile

The purpose of this article is to provide readers an account of the challenges and opportunities presented in a multi-faceted service-learning program in Romania. Developed in 2010, this endeavor involved an exploratory visit to assess the needs of social service agencies in Romania, and partnership with an American non-profit agency providing services to at-risk children. The mission of this program was to expose students to counseling as an emerging field in a developing post-communist community. In collaboration with the National Board of Certified Counselors-International (NBCC-I) Mental Health Facilitator (MHF) program, the authors were trained as Master Trainers in order to …


Two Counselors Integrate Two Integrational Approaches—Together [Book Chapter], Laura M. Schmuldt, Troyann I. Gentile Oct 2015

Two Counselors Integrate Two Integrational Approaches—Together [Book Chapter], Laura M. Schmuldt, Troyann I. Gentile

Troyann I. Gentile

No abstract provided.


Physical, Thermal And Spectral Properties Of Biofield Treated 3-Nitroacetophenone, Mahendra Kumar Trivedi, Rama Mohan Tallapragada, Alice Branton, Dahryn Trivedi, Gopal Nayak, Rakesh K. Mishra, Snehasis Jana Oct 2015

Physical, Thermal And Spectral Properties Of Biofield Treated 3-Nitroacetophenone, Mahendra Kumar Trivedi, Rama Mohan Tallapragada, Alice Branton, Dahryn Trivedi, Gopal Nayak, Rakesh K. Mishra, Snehasis Jana

Mahendra Kumar Trivedi

3-Nitroacetophenone (3-NAP) is an organic compound used as an intermediate for the synthesis of pharmaceutical agents. The aim of this study was to evaluate the impact of biofield energy treatment on the physical, thermal and spectral properties of 3-NAP. The study was performed in two groups i.e. control and treated. The control group remained as untreated, and the treated group received Mr. Trivedi’s biofield energy treatment. The control and treated 3-NAP samples were further characterized by X-ray diffraction (XRD), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), laser particle size analyzer, surface area analyzer, Fourier transform infrared (FT-IR) spectroscopy, and ultra …


Physical, Thermal And Spectral Properties Of Biofield Treated 1,2,3-Trimethoxybenzene, Mahendra Kumar Trivedi, Rama Mohan Tallapragada, Alice Branton, Dahryn Trivedi, Gopal Nayak, Rakesh K. Mishra, Snehasis Jana Oct 2015

Physical, Thermal And Spectral Properties Of Biofield Treated 1,2,3-Trimethoxybenzene, Mahendra Kumar Trivedi, Rama Mohan Tallapragada, Alice Branton, Dahryn Trivedi, Gopal Nayak, Rakesh K. Mishra, Snehasis Jana

Mahendra Kumar Trivedi

Study background: 1,2,3-Trimethoxybenzene is an important compound used for the synthesis of chemicals and pharmaceutical agents. The objective of this study was to investigate the influence of biofield energy treatment on the physical, thermal and spectral properties of 1,2,3-trimethoxybenzene.

Methods: The study was performed by dividing the sample into two groups (control and treated). The control group remained as untreated, while the treated group received Mr Trivedi’s biofield energy treatment. The control and treated 1,2,3-trimethoxybenzene samples were then characterized by X-ray diffraction (XRD), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), Fourier transform infrared (FT-IR) spectroscopy, and ultra violet-visible …


Physical, Thermal, And Spectroscopic Characterization Of Biofield Energy Treated Methyl-2-Naphthyl Ether, Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Gopal Nayak, Khemraj Bairwa, Snehasis Jana Sep 2015

Physical, Thermal, And Spectroscopic Characterization Of Biofield Energy Treated Methyl-2-Naphthyl Ether, Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Gopal Nayak, Khemraj Bairwa, Snehasis Jana

Mahendra Kumar Trivedi

Methyl-2-naphthyl ether (MNE) is an organic compound and used as the primary moiety for the synthesis of several antimicrobial and anti-inflammatory agents. This study was attempted to evaluate the impact of biofield energy treatment on the physical, thermal, and spectroscopic properties of MNE. The study was carried out in two groups i.e., control and treated. The treated group was subjected to Mr. Trivedi’s biofield treatment. Afterward, the control and treated samples of MNE were evaluated using X-ray diffraction (XRD), surface area analyzer, differential scanning calorimetry (DSC), thermogravimetric analysis-derivative thermogravimetric analysis (TGA-DTG), Fourier transform infrared (FT-IR), and ultraviolet-visible (UV-Vis) spectroscopy. The …


Evaluation Of The Impact Of Biofield Treatment On Physical And Thermal Properties Of Casein Enzyme Hydrolysate And Casein Yeas T Peptone, Mahendra Kumar Trivedi Jul 2015

Evaluation Of The Impact Of Biofield Treatment On Physical And Thermal Properties Of Casein Enzyme Hydrolysate And Casein Yeas T Peptone, Mahendra Kumar Trivedi

Mahendra Kumar Trivedi

In the present study, the influence of biofield treatment on physical and thermal properties of Casein Enzyme Hydrolysate (CEH) and Casein Yeast Peptone (CYP) were investigated. The control and treated samples were characterized by Fourier transform infrared (FT-IR) spectroscopy, differential scanning calorimetry (DSC), Thermo Gravimetric Analysis (TGA), particle size and surface area analysis. The FTIR results revealed that biofield treatment has caused reduction of amide group (amide-I and amide-II) stretching vibration peak that is associated with strong intermolecular hydrogen bonding in treated CEH as compared to control. However, no significant changes were observed in FTIR spectrum of treated CYP. The …


Iarc Monographs: 40 Years Of Evaluating Carcinogenic Hazards To Humans, Neil E. Pearce, Aaron Blair, Paolo Vineis, Wolfgang Ahrens, Aage Andersom, Josep M. Anto, Bruce K. Armstrong, Andrea A. Baccarelli, Frederick A. Beland, Amy Berrington, Pier Alberto Bertazzi, Linda S. Birnbaum, Ross C. Brownson, John R. Bucher, Kenneth P. Cantor, Elisabeth Cardis, John W. Cherrie, David C. Christiani, Pierluigi Cocco, David Coggon, Pietro Comba, Paul A. Demers, John M. Dement, Jeroen Douwes, Ellen A. Eisen, Lawrence S. Engel, Richard A. Fenske, Lora E. Fleming, Tony Fletcher, Elizabeth Fontham, Francesco Forastiere, Rainer Frentzel-Beyme, Lin Fritschi, Michel Gerin, Marcel Goldberg, Philippe Grandjean, Tom K. Grimsrud, Per Gustavsson, Andy Haines, Patricia Hartge, Johnni Hansen, Michael Hauptmann, Dick Heederik, Kari Hemminki, Denis Hemon, Irva Hertz-Picciotto, Jane A. Hoppin, James Huff, Bengt Jarvholm, Daehee Kang, Margaret R. Karagas Jun 2015

Iarc Monographs: 40 Years Of Evaluating Carcinogenic Hazards To Humans, Neil E. Pearce, Aaron Blair, Paolo Vineis, Wolfgang Ahrens, Aage Andersom, Josep M. Anto, Bruce K. Armstrong, Andrea A. Baccarelli, Frederick A. Beland, Amy Berrington, Pier Alberto Bertazzi, Linda S. Birnbaum, Ross C. Brownson, John R. Bucher, Kenneth P. Cantor, Elisabeth Cardis, John W. Cherrie, David C. Christiani, Pierluigi Cocco, David Coggon, Pietro Comba, Paul A. Demers, John M. Dement, Jeroen Douwes, Ellen A. Eisen, Lawrence S. Engel, Richard A. Fenske, Lora E. Fleming, Tony Fletcher, Elizabeth Fontham, Francesco Forastiere, Rainer Frentzel-Beyme, Lin Fritschi, Michel Gerin, Marcel Goldberg, Philippe Grandjean, Tom K. Grimsrud, Per Gustavsson, Andy Haines, Patricia Hartge, Johnni Hansen, Michael Hauptmann, Dick Heederik, Kari Hemminki, Denis Hemon, Irva Hertz-Picciotto, Jane A. Hoppin, James Huff, Bengt Jarvholm, Daehee Kang, Margaret R. Karagas

Dartmouth Scholarship

Background: Recently, the International Agency for Research on Cancer (IARC) Programme for the Evaluation of Carcinogenic Risks to Humans has been criticized for several of its evaluations, and also for the approach used to perform these evaluations. Some critics have claimed that failures of IARC Working Groups to recognize study weaknesses and biases of Working Group members have led to inappropriate classification of a number of agents as carcinogenic to humans.

Objectives: The authors of this Commentary are scientists from various disciplines relevant to the identification and hazard evaluation of human carcinogens. We examined criticisms of the IARC classification process …


Health Disclaimers And Website Credibility Markers: Guidance For Consumer Health Reference In The Affordable Care Act Era, Deborah H. Charbonneau Jan 2015

Health Disclaimers And Website Credibility Markers: Guidance For Consumer Health Reference In The Affordable Care Act Era, Deborah H. Charbonneau

Deborah H. Charbonneau

This article reports on the current state of health disclaimers, online health resources, and credibility markers provided on public library websites (N = 105) for those seeking health information. In light of the Affordable Care Act (ACA), these findings have implications for consumer health reference services in public libraries. Approximately half of the public library websites in the study sample (n = 52, 49.5%) referred users to the ACA Health Insurance Marketplace website (HealthCare.gov). When referring to online consumer health resources, a small number of public library websites identified the authors of online health content (n = 16, 15.2%) or …


Animal Models And Therapeutic Molecular Targets Of Cancer: Utility And Limitations., Maria Cekanova Ms, Rndr, Phd, Kusum Rathore Oct 2014

Animal Models And Therapeutic Molecular Targets Of Cancer: Utility And Limitations., Maria Cekanova Ms, Rndr, Phd, Kusum Rathore

Maria Cekanova MS, RNDr, PhD

Cancer is the term used to describe over 100 diseases that share several common hallmarks. Despite prevention, early detection, and novel therapies, cancer is still the second leading cause of death in the USA. Successful bench-to-bedside translation of basic scientific findings about cancer into therapeutic interventions for patients depends on the selection of appropriate animal experimental models. Cancer research uses animal and human cancer cell lines in vitro to study biochemical pathways in these cancer cells. In this review, we summarize the important animal models of cancer with focus on their advantages and limitations. Mouse cancer models are well known, …


Accelerated Resolution Therapy For Treatment Of Pain Secondary To Symptoms Of Combat-Related Posttraumatic Stress Disorder, Kevin E. Kip, Laney Rosenzweig, Diego F. Hernandez, Amy Shuman, David M. Diamond, Sue Ann Girling, Kelly L. Sullivan, Trudy R. Wittenberg, Ann M. Witt, Cecile A. Lengacher, Brian Anderson, Susan C. Mcmillan May 2014

Accelerated Resolution Therapy For Treatment Of Pain Secondary To Symptoms Of Combat-Related Posttraumatic Stress Disorder, Kevin E. Kip, Laney Rosenzweig, Diego F. Hernandez, Amy Shuman, David M. Diamond, Sue Ann Girling, Kelly L. Sullivan, Trudy R. Wittenberg, Ann M. Witt, Cecile A. Lengacher, Brian Anderson, Susan C. Mcmillan

Kelly L. Sullivan

Background: As many as 70% of veterans with chronic pain treated within the US Veterans Administration (VA) system may have posttraumatic stress disorder (PTSD), and conversely, up to 80% of those with PTSD may have pain. We describe pain experienced by US service members and veterans with symptoms of PTSD, and report on the effect of Accelerated Resolution Therapy (ART), a new, brief exposure-based therapy, on acute pain reduction secondary to treatment of symptoms of PTSD.
Methods: A randomized controlled trial of ART versus an attention control (AC) regimen was conducted among 45 US service members/veterans with symptoms of combat-related …


Mycobacterium Ulcerans Fails To Infect Through Skin Abrasions In A Guinea Pig Infection Model: Implications For Transmission, H R. Williamson, L Mosi, Robert L. Donnell, M Aqqad, R W. Merritt, P L. Small Apr 2014

Mycobacterium Ulcerans Fails To Infect Through Skin Abrasions In A Guinea Pig Infection Model: Implications For Transmission, H R. Williamson, L Mosi, Robert L. Donnell, M Aqqad, R W. Merritt, P L. Small

Robert L Donnell DVM, Ph.D., DACVP College of Veterinary Medicine

Transmission of M. ulcerans, the etiological agent of Buruli ulcer, from the environment to humans remains an enigma despite decades of research. Major transmission hypotheses propose 1) that M. ulcerans is acquired through an insect bite or 2) that bacteria enter an existing wound through exposure to a contaminated environment. In studies reported here, a guinea pig infection model was developed to determine whether Buruli ulcer could be produced through passive inoculation of M. ulcerans onto a superficial abrasion. The choice of an abrasion model was based on the fact that most bacterial pathogens infecting the skin are able to …


Evaluating Quality Improvement To Improve Hiv Reporting, Nandi A. Marshall, William C. Livingood, Angela Peden, Gulzar H. Shah, Russ Toal, Dayna Alexander, Alesha Wright, Sandra Jump, Shelby Freeman, Kay Davis, Lynn Woodhouse, Kellie Penix Feb 2014

Evaluating Quality Improvement To Improve Hiv Reporting, Nandi A. Marshall, William C. Livingood, Angela Peden, Gulzar H. Shah, Russ Toal, Dayna Alexander, Alesha Wright, Sandra Jump, Shelby Freeman, Kay Davis, Lynn Woodhouse, Kellie Penix

Russell B. Toal

The incorporation and evaluation of Quality Improvement into Georgia’s public health systems continues to be a focus of the Georgia Public Health Practice Based Research Network. This report describes the process, preliminary results and lessons learned from incorporating Quality Improvement into one of Georgia’s public health districts.


Magnetic Resonance Imaging (Mri) Spinal Cord And Canal Measurements In Normal Dogs, Silke Hecht, M M. Huerta, Robert B. Reed Feb 2014

Magnetic Resonance Imaging (Mri) Spinal Cord And Canal Measurements In Normal Dogs, Silke Hecht, M M. Huerta, Robert B. Reed

Silke Hecht

The goal of this study was to establish Magnetic resonance imaging (MRI) reference ranges for spinal measurements in normal dogs. Forty dogs (1–10 kg, 11–20 kg, 21–30 kg, > 30 kg; 10 dogs per category) underwent spinal MRI. Measurements were performed on sagittal T2-W images at the level of the 4th thoracic vertebra (T4), the 9th thoracic vertebra (T9) and the 3rd lumbar vertebra (L3). Spinal canal diameter (mm) ranged from 6.07 ± 0.63 (1–10 kg) to 8.27 ± 1.15 (> 30 kg) at the level of T4; 6.55 ± 0.61 (1–10 kg) to 9.04 ± 1.26 (> 30 kg) at …


From The Outside Looking In: A Response To The Hijacking Of Recreational Therapy, Daniel L. Dustin, Kelly S. Bricker, Keri A. Schwab Jan 2014

From The Outside Looking In: A Response To The Hijacking Of Recreational Therapy, Daniel L. Dustin, Kelly S. Bricker, Keri A. Schwab

Keri Schwab

Where does Dr. Austin want his line of thought to lead and what does he expect from the larger field of parks and recreation in return? Is he after reassurance that recreational therapy is valued by the rest of us? Does he want recreation therapists to be acknowledged as the closest thing we have in our midst to medical doctors? Or does he want recreational therapy to disassociate itself from the field of parks and recreation altogether? If recreation therapists want to be viewed as distinct and different from the rest of us, if it is autonomy they are after, …


Treatment Of Neurodegenerative Ataxias With Intravenous Immune Globulin, Theresa A. Zesiewicz, Seok Hun Kim, Kelly L. Sullivan, Jeannie Stephenson, Israt Jahan, Susan L. Perlman, Jessica D. Shaw, Tuan Vu, Clifton L. Gooch Jan 2014

Treatment Of Neurodegenerative Ataxias With Intravenous Immune Globulin, Theresa A. Zesiewicz, Seok Hun Kim, Kelly L. Sullivan, Jeannie Stephenson, Israt Jahan, Susan L. Perlman, Jessica D. Shaw, Tuan Vu, Clifton L. Gooch

Kelly L. Sullivan

Background: Neurodegenerative ataxias, including spinocerebellar ataxias (SCAs), are progressive diseases without effective treatment. There is preclinical evidence that inflammation may contribute to neuronal injury in several neurodegenerative ataxias. Intravenous immune globulin (IVIG) is a therapeutic modality that is used as treatment of several autoimmune and inflammatory disorders.
Methods: The primary objective of this open-label pilot study was to assess the effect of IVIG on neurodegenerative ataxias as measured by total scale for the assessment and rating of ataxia (SARA) score. Three patients received IVIG (2 g/kg of body weight, divided over 5 days) once monthly for 3 months, and were …