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Oral Medicine and Surgical Sciences Issue (Oral Medicine, Oral and Maxillofacial Surgery, Oral Pathology, Oral Biology)
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Evaluation Of Local Versus Intravenous Administration Of Adipose Tissue-Derived Stem Cells On Regeneration Of Oral Epithelium Of Chemotherapy Treated Rats, Esraa Ibrahim, Heba Adawy, Nawal Lasheen, Mena Abd Allah
Evaluation Of Local Versus Intravenous Administration Of Adipose Tissue-Derived Stem Cells On Regeneration Of Oral Epithelium Of Chemotherapy Treated Rats, Esraa Ibrahim, Heba Adawy, Nawal Lasheen, Mena Abd Allah
Al-Azhar Journal of Dentistry
Purpose: This study aimed to evaluate the effect of local and intravenous administration of adipose tissue-derived stem cells on the regeneration of oral epithelium in chemotherapy-treated rats. Material and Methods: 48 adult male albino rats were used in this study throughout the experimental period (2 weeks). 12 rats were left as negative controls (G I) and the remaining experimental 36 rats were treated with 5-fluorouracil (chemotherapeutic agent) in a dose of 50 mg/kg/dose to induce oral mucositis. Moreover, acetic acid was injected in the buccal mucosa to produce ulcers and then the rats were subdivided into three subgroups, (G II) …
Possible Ameliorative Impact Of Curcumin On Regressive Changes Induced By Diabetes On Parotid Glands Of Albino Rats, Menatalla Elhindawy, Islam Ateia, Samah Ezzat
Possible Ameliorative Impact Of Curcumin On Regressive Changes Induced By Diabetes On Parotid Glands Of Albino Rats, Menatalla Elhindawy, Islam Ateia, Samah Ezzat
Al-Azhar Journal of Dentistry
Purpose: Diabetes mellitus (DM) has deleterious effect on various body organs especially salivary glands. Therefore, this study was conducted to evaluate the therapeutic effect of curcumin on parotid salivary glands in diabetic rats. Material andmethods: Fifty-six adult male albino rats weighting 150-200 g were selected and divided into two equal groups n= 28 rats each. Diabetes was induced in both groups I (Diabetic) & II (Diabetic & curcumin) with a single intraperitoneal injection of streptozotocin (STZ) at a dose of 55 mg/kg. After 2 weeks of diabetes confirmation; rats of group II received 200 mg\kg of curcumin orally once daily. …
Comparison Between Two Computer Designed Custom Made Miniplates For The Treatment Of Mandibular Angle Fractures, Aya Ahmed, Susan Hassan, Fatma Mohamed, Usama El Dakrory
Comparison Between Two Computer Designed Custom Made Miniplates For The Treatment Of Mandibular Angle Fractures, Aya Ahmed, Susan Hassan, Fatma Mohamed, Usama El Dakrory
Al-Azhar Journal of Dentistry
Purpose: To evaluate the clinical and radiographic outcomes of mandibular angle fractures (MAF), which were managed with two different computer designed custom made miniplates. Materials and Methods: Eight patients complaining of MAF were included in this study and divided into two equal groups. In group 1, the MAF were fixed with regular design custom made miniplates that were adapted at the superior border of external oblique ridge. Patients in group 2 received custom made miniplates with one straight section adapted to the superior border of external oblique ridge and two lateral extensions adapted to the buccal cortex; proximal and distal …
Efficacy Of Aloe Vera In Treatment Of Experimentally Induced Oral Lichenoid Reaction, Hind Mohmed, Mai Attia, Lobna Abd-Alaziz, Aya Dawaba, Noura Bakr
Efficacy Of Aloe Vera In Treatment Of Experimentally Induced Oral Lichenoid Reaction, Hind Mohmed, Mai Attia, Lobna Abd-Alaziz, Aya Dawaba, Noura Bakr
Al-Azhar Journal of Dentistry
Purpose: the present study was conducted to compare the efficacy of herbal treatment using Aloe Vera in induced lichenoid reaction versus topical steroids. Materials and methods: thirty-six rats were divided into four groups: 1stgroup control normal group with no induced oral lesions, 2ndgroup (Negative control group) with induced oral lesions but no treatment was used, 3rdgroup (Positive control group) treated with triamcinolone acetonide 0.1% paste, in the 4thgroup(Aloe vera group) treated with topical Aloe vera gel, rats in the 3rd and 4th groups are treated topically for 15 days, samples were taken from the buccal mucosa after the end of …
Effects Of Some Types Of Smoking On The Outcome Of Non-Surgical Periodontal Therapy Of Periodontitis Patients., Nouran Abdelmaged, Osama El-Shall, Zienab Farid
Effects Of Some Types Of Smoking On The Outcome Of Non-Surgical Periodontal Therapy Of Periodontitis Patients., Nouran Abdelmaged, Osama El-Shall, Zienab Farid
Al-Azhar Journal of Dentistry
Purpose: The aim of the current study was to compare and contrast the effects of various smoking types. This study focused on traditional cigarettes, electronic cigarettes and heated tobacco products compared with non-smokers on the outcome of non-surgical treatment of moderate generalized periodontitis. Subjects and methods: The present study included a total of sixty (60) patients with moderate generalized chronic periodontitis. They were divided into four equivalent groups to be managed with non-surgical mechanical debridement. The clinical results of the study were evaluated using Plaque Index, Gingival Index, Pocket depth measurements, and Clinical attachment level. The clinical measurements were obtained …
Evaluation Of Dose Dependent Chemopreventive Effect Of Diosmin On Induced Oral Squamous Cell Carcinoma, Menna-Tallah Osman, Amany Taha, Nadia Radi, Eman Abohager
Evaluation Of Dose Dependent Chemopreventive Effect Of Diosmin On Induced Oral Squamous Cell Carcinoma, Menna-Tallah Osman, Amany Taha, Nadia Radi, Eman Abohager
Al-Azhar Journal of Dentistry
Purpose: This study aimed to evaluate the chemoprevention efficacy of diosmin on experimentally induced hamster buccal pouch (HBP) squamous cell carcinoma utilizing Ki 67 as a proliferative marker. Material and Methods: Seventy Syrian male hamsters were used as experimental animals, these hamsters were divided into five groups, Group I (negative control): 5 hamsters were left untreated. Group II (DMBA treated group): 20 hamsters were divided equally into two subgroups, painted with 0.5% DMBA where subgroup IIa: for 8 weeks while subgroup IIb: for 14 weeks. Group III: 5 hamsters were orally administrated diosmin 150 mg/kg for 14 weeks. Group IV: …
Evaluation Of Photodynamic Therapy Using Diode Laser With Photosensitizer In Treatment Of Chronic Periodontitis, Doaa Bhgaat, Hamdy Nassar, Naglaa Elkilani, Eman Kandeel
Evaluation Of Photodynamic Therapy Using Diode Laser With Photosensitizer In Treatment Of Chronic Periodontitis, Doaa Bhgaat, Hamdy Nassar, Naglaa Elkilani, Eman Kandeel
Al-Azhar Journal of Dentistry
Purpose: The current clinical study was conducted to evaluate clinical and biochemical effects of photodynamic therapy in treatment of periodontal disease. Material and methods: The current study was conducted on twenty-eight (28) sites in fourteen (14) patients. A spilt-mouth design was used, sites were randomly selected from each patient, and assigned into two groups:(control group A) fourteen (14) sites received scaling and root planning only, and (test group B): fourteen (14) sites received PDT (Curcumin as photosensitizer agent was irradiated by diode laser beam) and another group without any laser beam in oral cavity, 5 patients received SRP only. Clinical …
Assessment Of Absorbed Radiation Dose Of Some Soft And Hard Oral Tissues After Panoramic And Cone Beam Ct Radiograph, Aya Talha, Ossama El-Shall, Aya Abaza, Nora Abdelgawad
Assessment Of Absorbed Radiation Dose Of Some Soft And Hard Oral Tissues After Panoramic And Cone Beam Ct Radiograph, Aya Talha, Ossama El-Shall, Aya Abaza, Nora Abdelgawad
Al-Azhar Journal of Dentistry
Purpose: The goal of the this study is to measure absorbed dose of oral tissues such as oral mucosa, salivary gland and bone after exposure to ionizing radiation through panoramic radiograph and cone beam CT. Subjects and Methods: about 50 Egyptian patients were selected in this study who were referred to the department of oral medicine, periodontology, oral diagnosis & radiology, Faculties of Dental Medicine, Al-Azhar university for panoramic or cone beam examination for various dental purposes. Patients were divided into two groups (25 patients each). First Group was subjected to panoramic examination and the second one was subjected to …
Prevalence Of Temporomandibular Joints Disorders In Egyptian Undergraduate Dental Students And The Association Between The Clinical And Radiographic Findings, Esraa Gomaa, Naglaa El-Kilani, Mostafa Abdel-Ghany, Noura Abd El-Gawad
Prevalence Of Temporomandibular Joints Disorders In Egyptian Undergraduate Dental Students And The Association Between The Clinical And Radiographic Findings, Esraa Gomaa, Naglaa El-Kilani, Mostafa Abdel-Ghany, Noura Abd El-Gawad
Al-Azhar Journal of Dentistry
Purpose: to assess the prevalence of temporomandibular disorders among dental undergraduate Egyptian students and the association between the clinical features and radiographic findings. Material and Methods: 281 female dental undergraduate students were randomly selected to participate in the primary screening. In the study screening examination and final diagnosis were done according to a new modified Diagnostic Criteria for TMD (DC/TMD) Axis I which encompass (medical history, primary pain screening questionnaire, signs and symptoms questionnaire and examination protocol). The examination consisted of 11 criteria (pain location, headache location, incisal relationship ,opening pattern ,opening movement ,lateral and protrusive movements ,noises during opening …
Possible Proliferative Impact Of Human Platelet-Rich Fibrin Obtained From Controlled Type 2 Diabetic Patients On Human Dental Pulp Stem Cells (In Vitro Study), Mona Amer, Menatalla Elhindawy, Ahmed Zaher
Possible Proliferative Impact Of Human Platelet-Rich Fibrin Obtained From Controlled Type 2 Diabetic Patients On Human Dental Pulp Stem Cells (In Vitro Study), Mona Amer, Menatalla Elhindawy, Ahmed Zaher
Al-Azhar Journal of Dentistry
Purpose: This study was carried out in order to assess the effect of 10% PRF exudate obtained from controlled type 2 diabetic patients on proliferation capacity of dental pulp stem cells (DPSCs). Then 1% PRF exudate obtained from controlled type 2 diabetic patients was tested for osteogenic capability after 1 week. Material and methods: PRF exudates were prepared using the direct method from 8 healthy donors (control group) and 8 controlled type 2 diabetic patients (study group). In 96-well plates, DPSCs harvested from pulp tissue of impacted lower third molar were treated with 10% PRF exudate obtained from healthy donors …
Comparison Between Chitosan Hydrogel And Recaldent Paste In Enamel Re-Mineralization Of Induced Enamel Demineralized Lesions, Nada Desouky, Mostafa Abd El-Gany, Heba Adawy, Nehad Ahmed
Comparison Between Chitosan Hydrogel And Recaldent Paste In Enamel Re-Mineralization Of Induced Enamel Demineralized Lesions, Nada Desouky, Mostafa Abd El-Gany, Heba Adawy, Nehad Ahmed
Al-Azhar Journal of Dentistry
Purpose: This study aimed to compare between the effect of chitosan and GC MI paste plus on re-mineralization of demineralized enamel in-vitro. Subjects and methods: Extracted upper premolars from orthodontic patients. Sample premolars were examined one by scanning electron microscope with energy dispersive X-ray spectroscopy to determine the Ca/P ratio before demineralization and the other by Fourier transform Infrared spectroscopy to determine the degree of conversion of bonds. After demineralization, two premolars samples were selected; one was examined by scanning electron microscope with energy dispersive X-ray spectroscope and the other was examined by FTIR to determine the degree of conversion …
Evaluation Of Cytotoxic Effect Of Betanin Nanoparticles Against Squamous Cell Carcinoma Cell Line Compared To Doxorubicin, Noha Hassanine, Amany Taha, Eman Abohager
Evaluation Of Cytotoxic Effect Of Betanin Nanoparticles Against Squamous Cell Carcinoma Cell Line Compared To Doxorubicin, Noha Hassanine, Amany Taha, Eman Abohager
Al-Azhar Journal of Dentistry
Purpose: This study was aimed to evaluate the anticancer effect of nano sized betanine particles (betanine NP) on squamous cell carcinoma cell line compared to doxorubicin (DOX) using cytotoxicity assay. Materials and Methods: Human tongue squamous cell carcinoma cell line (SCC 25) were cultured to obtain 3 groups, two of them were subjected to DOX and the betanine NP. The third group was not subjected to treatment and used as negative control. Different concentrations of betanin NP and DOX were applied on SCC25 to choose the doses with high cytotoxic effects according to their IC50 using the methyl thiazolyl tetrazolium …
Regenerative Potentiality Of Concentrated Growth Factors With Partially And Completely Amputated Pulp Tissue (Histological Study), Abeer Ezzat, Heba Adawy, Mena Abd Allah
Regenerative Potentiality Of Concentrated Growth Factors With Partially And Completely Amputated Pulp Tissue (Histological Study), Abeer Ezzat, Heba Adawy, Mena Abd Allah
Al-Azhar Journal of Dentistry
Purpose: This study aimed to investigate the effect of concentrated growth factors (CGF) with partially and completely amputated pulp tissue on the histologic outcome of dentin-pulp complex regeneration in immature dogs’ teeth with non-infected pulp and apical tissue. Materials and Methods: In this study fifty six immature teeth in four mongrel dogs were involved and simple randomization design was used. The teeth were divided into four groups; group (I): the teeth were left with no treatment (negative control), group (II): the teeth underwent complete pulp extirpation where blood clots filled the root canals (positive control), group (III): the root canals …
Assessment Of Dimensional Ridge Changes After Augmentation Using External Oblique Ridge With Or Without Computer Surgical Guide, Amira Abouelyazid, Hatem Al Ahmady, Fawzi Alsayed, Hanan Reda
Assessment Of Dimensional Ridge Changes After Augmentation Using External Oblique Ridge With Or Without Computer Surgical Guide, Amira Abouelyazid, Hatem Al Ahmady, Fawzi Alsayed, Hanan Reda
Al-Azhar Journal of Dentistry
Purpose: The current study was conducted to evaluate, clinically and radiographically, the results of defective ridge augmentation by external oblique ridge graft with or without the use of computer-generated surgical guide. Patients and methods: Twelve patients with alveolar ridges defect were included in this study. The patients were divided into 2 groups: Group A; The alveolar ridges defect augmentation from external oblique ridge graft using Khoury technique with computer- designed generated surgical guides. Group B; The alveolar ridges defect augmentation from external obliqueridge graft using traditional Khoury technique. Clinical and radiographic follow up was performed for 6 months. Treatment changes …
Evaluation Of The Addition Of Injectable Platelet Rich Fibrin To Xenograft In Management Of Periodontal Intraosseous Defects. “Randomized Controlled Trial”, Ahmed Elbarbary, Ahmed Reda, Ahmed Abd Elaziz
Evaluation Of The Addition Of Injectable Platelet Rich Fibrin To Xenograft In Management Of Periodontal Intraosseous Defects. “Randomized Controlled Trial”, Ahmed Elbarbary, Ahmed Reda, Ahmed Abd Elaziz
Al-Azhar Journal of Dentistry
Purpose: Platelet rich fibrin (PRF) has been widely and successfully used in periodontal regeneration. Injectable PRF (i PRF) is a liquid form of PRF containing more leucocyte and growth factors. I-PRF was used with great success in management of gingival recession and implant therapy. So the aim of the study was to evaluate the benefit of adding i-PRF to xenograft in management of periodontal intraosseous defects. Subjects and Methods: Twenty four patients (age range 36 - 59 years), with stage III periodontitis with at least one intrabony defect, probing pocket depth > 5 mm and radiographic evidence of vertical bone loss, …
Evaluation Of Anticarcinogenic Potential Of Broccoli Extract On Oral Squamous Cell Carcinoma Cell Line, Doaa Habba, Nadia Radi, Eman Abo Hager
Evaluation Of Anticarcinogenic Potential Of Broccoli Extract On Oral Squamous Cell Carcinoma Cell Line, Doaa Habba, Nadia Radi, Eman Abo Hager
Al-Azhar Journal of Dentistry
Purpose: The current research was conducted to estimate the anticarcinogenic effect of sulforaphane (SFN) combined with different doses of the chemotherapeutic agent cisplatin (CIS) on the cell line of Squamous cell carcinoma orally to consider sulforaphane (Broccoli extract) Outcome on cell viability and apoptosis of the oral squamous cell carcinoma cell line. Subjects and Method: Squamous cell carcinoma of the human tongue (SCC9) cell line subcultured to obtain 6 study groups, which were subjected to SFN, CIS with low dose, CIS with high dose and a combination of both (SFN with CIS in low concentration = mix1 and SFN with …
Three-Dimensional Measuring Of Zygomaticomaxillary Complex Symmetry After Fixation Of Unilateral Zygomaticomaxillary Complex Fracture, Mahetab Montaser, Fatma Khalifa, Fatma Mohamed, Wael Shawkat
Three-Dimensional Measuring Of Zygomaticomaxillary Complex Symmetry After Fixation Of Unilateral Zygomaticomaxillary Complex Fracture, Mahetab Montaser, Fatma Khalifa, Fatma Mohamed, Wael Shawkat
Al-Azhar Journal of Dentistry
Purpose: to evaluate the symmetry of the reduced unilateral zygomaticomaxillary complex (ZMC) fractures fixed with computer designed custom machined titanium miniplate and conventional titanium miniplate, using three dimensional computed tomography (3D-CT) analysis of ZMC position. Patients and Methods: Ten patients who suffered from unilateral ZMC fractured were involved in this study. The patients were randomly and equally divided into two groups. In group A, the ZMC fractures were reduced and fixed with computer designed custom machined titanium miniplates, whereas in group B, they were fixed by conventional 2.0mm titanium miniplates. Computed Tomography (CT) scan was performed for each patient pre …
Effect Of Systemic Administration Of Simvastatin On Dental Implant Stability, Aya Sharaf Eldeen, Osama El-Shall, Mai Attia
Effect Of Systemic Administration Of Simvastatin On Dental Implant Stability, Aya Sharaf Eldeen, Osama El-Shall, Mai Attia
Al-Azhar Journal of Dentistry
Purpose: This study was designed to evaluate implant stability in partially edentulous patients by investigating the effect of systemic simvastatin administration on the bone regeneration around the dental implant. Patients and Methods: A total of 18 patients were divided into two groups. Group I:9 healthy patients underwent a one-stage titanium screw-type endosseous dental implant and Group П:9 patients on simvastatin therapy (20 mg daily) as a prophylaxis drug, underwent the same type of one stage titanium screw type of endosseous dental implant as the control group. Modified plaque index (MPI), Probing depth (PD) and Modified Gingival Index (MGI) were recorded. …
Evaluation Of Laser Assisted Ridge Preservation Combined With Platelet Rich Fibrin And /Or Bone, Rehab Osman, Naglaa Elkilani, Heba Adawy, Mai Attia
Evaluation Of Laser Assisted Ridge Preservation Combined With Platelet Rich Fibrin And /Or Bone, Rehab Osman, Naglaa Elkilani, Heba Adawy, Mai Attia
Al-Azhar Journal of Dentistry
Purpose: The main target of our split mouth randomized controlled clinical trial was to evaluate how well laser assisted ridge preservation worked in conjunction with platelet rich fibrin (PRF) and/or bone clinical and radiographically. Subjects and Methods: Thirty extraction sockets from ten patients were split into three groups at random; group I treated by PRF and bone graft after atraumatic extraction, group II (PRF and laser assisted socket preservation) and group III (PRF, bone graft and laser assisted socket preservation). Width and height of the alveolar ridge observed at baseline, three and six months after treatment. Bone density recorded at …
Assessment Of Resistin Level Using Azithromycin As An Adjunctive To Non-Surgical Treatment Of Periodontitis Patients With Type Ii Diabetes Mellitus, Nora Hegab, Mai Attia, Olfat Shaker
Assessment Of Resistin Level Using Azithromycin As An Adjunctive To Non-Surgical Treatment Of Periodontitis Patients With Type Ii Diabetes Mellitus, Nora Hegab, Mai Attia, Olfat Shaker
Al-Azhar Journal of Dentistry
Purpose: This study was designed to evaluate the resistin levels in gingival crevicular fluid (GCF) of patients suffering from periodontitis and type II diabetes mellitus (TIIDM) after non-surgical periodontal therapy and Azithromycin (AZM) as adjunctive therapy. Subjects and Methods: 48 patients with periodontitis their age ranging between (20-50) years old were selected for this study were divided into three groups: (group I): healthy patients with periodontitis, (group II): controlled TIIDM patients with periodontitis, and (group III): controlled TIIDM patients with periodontitis who were received AZM. All patients received non-surgical periodontal therapy (NSPT) and were examined with the following clinical periodontal …