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Medicine and Health Sciences

1997

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What's Happening: December 24, 1997, Maine Medical Center Dec 1997

What's Happening: December 24, 1997, Maine Medical Center

What's Happening

No abstract provided.


A Linkage Map Of The Canine Genome, Cathryn Mellersh, Amelia Langston, Gregory Acland, Melissa Fleming, Kunal Ray, Neil Weigand, Leigh Francisco, Mark Gibbs, Gustavo Aguirre, Elaine Ostrander Dec 1997

A Linkage Map Of The Canine Genome, Cathryn Mellersh, Amelia Langston, Gregory Acland, Melissa Fleming, Kunal Ray, Neil Weigand, Leigh Francisco, Mark Gibbs, Gustavo Aguirre, Elaine Ostrander

Gustavo D. Aguirre, VMD, PhD

A genetic linkage map of the canine genome has been developed by typing 150 microsatellite markers using 17 three-generation pedigrees, composed of 163 F2individuals. One hundred and thirty-nine markers were linked to at least one other marker with a lod score ≥ 3.0, identifying 30 linkage groups. The largest chromosome had 9 markers spanning 106.1 cM. The average distance between markers was 14.03 cM, and the map covers an estimated 2073 cM. Eleven markers were informative on the mapping panel, but were unlinked to any other marker. These likely represent single markers located on small, distinct canine chromosomes. This map …


Construction Of A Panel Of Canine–Rodent Hybrid Cell Lines For Use In Partitioning Of The Canine Genome, Amelia A. Langston, Cathryn S. Mellersh, Cassandra L. Neal, Kunal Ray, Gregory M. Acland, Mark Gibbs, Gustavo D. Aguirre, R.E. K. Fournier, Elaine A. Ostrander Dec 1997

Construction Of A Panel Of Canine–Rodent Hybrid Cell Lines For Use In Partitioning Of The Canine Genome, Amelia A. Langston, Cathryn S. Mellersh, Cassandra L. Neal, Kunal Ray, Gregory M. Acland, Mark Gibbs, Gustavo D. Aguirre, R.E. K. Fournier, Elaine A. Ostrander

Gustavo D. Aguirre, VMD, PhD

We have constructed a collection of canine–rodent microcell hybrid cell lines by fusion of canine fibroblast microcell donors with immortalized rodent recipient cells. Characterization of the hybrid cell lines using a combination of fluorescencein situhybridization and PCR analysis of canine microsatellite repeat sequences allowed selection of a panel of hybrids in which most canine chromosomes are represented. Approximately 90% of genetic markers and genes that were tested could be assigned to 1 of 31 anonymous canine chromosome groups, based on common patterns of retention in the hybrid set. Many of these putative chromosome groups have now been validated …


What's Happening: December 10, 1997, Maine Medical Center Dec 1997

What's Happening: December 10, 1997, Maine Medical Center

What's Happening

No abstract provided.


Examination Of Benefits Of Binaural Auditory Stimulation For Children With A Cochlear Implant And A Hearing Aid In The Contralateral Ear, Evonne Nicol Altesleben Dec 1997

Examination Of Benefits Of Binaural Auditory Stimulation For Children With A Cochlear Implant And A Hearing Aid In The Contralateral Ear, Evonne Nicol Altesleben

Dissertations and Theses

Congenital or acquired hearing impairments put children at risk of delayed language development. Today the cochlear implant (Cl) is a viable amplification option for some children with profound hearing losses. Audiologists often recommend that children with hearing impairments be fitted with binaural hearing aids in the hope that maximum stimulation will occur and that auditory deprivation will be lessened. An area lacking investigation is whether binaural stimulation will be beneficial to the cochlear implant recipient.Controversy also exists regarding the use of a hearing aid in the non-implanted ear.

The focus of this study was to compare binaural auditory stimulation benefits …


Alterations In Calcium Homeostasis And The Insulin-Like Growth Factor Signaling Pathway Induced By Carcinogenic Polycyclic And Halogenated Aromatic Hydrocarbons In Human Mammary Epithelial Cells, Stacey L. Tannheimer Dec 1997

Alterations In Calcium Homeostasis And The Insulin-Like Growth Factor Signaling Pathway Induced By Carcinogenic Polycyclic And Halogenated Aromatic Hydrocarbons In Human Mammary Epithelial Cells, Stacey L. Tannheimer

Pharmaceutical Sciences ETDs

Breast cancer is a major health concern for women, with only a small percent of the risk factors currently identified. It has been estimated that environmental factors may contribute to up to 80% of breast cancer cases. Many environmental carcinogens, such as polycyclic and halogenated aromatic hydrocarbons (PAHs and HAHs), are proven mammary carcinogens in animal models. Therefore, these studies were conducted to elucidate potential roles of PAHs and HAHs in alterations in known signaling pathways in human mammary epithelial cells (HMEC). Carcinogenic PAHs have previously been shown to produce sustained alterations in the calcium (Ca2') homeostasis of lymphocytes Therefore, …


Spruce Run News (December 1997), Spruce Run Staff Dec 1997

Spruce Run News (December 1997), Spruce Run Staff

Maine Women's Publications - All

No abstract provided.


Interaction Of Gaba And Excitatory Amino Acids In The Basolateral Amygdala: Role In Cardiovascular Regulation, Robert P. Soltis, Jennifer C. Cook, Adam E. Gregg, Brian J. Sanders Dec 1997

Interaction Of Gaba And Excitatory Amino Acids In The Basolateral Amygdala: Role In Cardiovascular Regulation, Robert P. Soltis, Jennifer C. Cook, Adam E. Gregg, Brian J. Sanders

Scholarship and Professional Work – COPHS

Activation of the amygdala in rats produces cardiovascular changes that include increases in heart rate and arterial pressure as well as behavioral changes characteristic of emotional arousal. The objective of the present study was to examine the interaction of GABA and excitatory amino acid (EAA) receptors in the basolateral amygdala (BLA) in regulating cardiovascular function. Microinjection of the GABAA receptor antagonist bicuculline methiodide (BMI) or the E A A receptor agonists NMDA or AMPA into the same region of the BLA of conscious rats produced dose-related increases in heart rate and arterial pressure. Injection of the nonselective EAA receptor …


Flight Physician - December, 1997, Civil Aviation Medical Association Dec 1997

Flight Physician - December, 1997, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A fourteen page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.


A Comparative Study Of Nursing And Non-Nursing Majors Knowledge And Attitudes Toward Hiv And Aids At The Sophomore And Senior Level, Diana R. Lubandi Dec 1997

A Comparative Study Of Nursing And Non-Nursing Majors Knowledge And Attitudes Toward Hiv And Aids At The Sophomore And Senior Level, Diana R. Lubandi

Electronic Dissertations and Theses

The primary purpose of this study was to examine the impact of a baccalaureate nursing program on the knowledge and attitudes of United States nursing students towards HIV/AIDS. Mathematics and engineering majors were used as a comparison group and to control the threats to internal validity of history and maturation. Data for this study was obtained using an AIDS Knowledge Scale and an AIDS Attitude Scale in the form of questionnaires. A convenience sample of 103 students comprised of 30 sophomore nursing students, 34 senior nursing students, 16 sophomore Non nursing students and 23 senior non-nursing students was utilized. The …


The Morality Of Intimate Faculty-Student Relationships, Nicholas Dixon Dec 1997

The Morality Of Intimate Faculty-Student Relationships, Nicholas Dixon

Center for the Study of Ethics in Society Papers

Presented September 19, 1996 for the Center for the Study of Ethics in Society


Further Characterization Of A Complement-Sensitive Mutant Of A Virulent Avian Escherichia Coli Isolate, Theodore J. Kottom, Lisa K. Nolan, Michael Robinson, John Brown, Tom Gustad, Shelley M. Horne, Catherine W. Giddings Dec 1997

Further Characterization Of A Complement-Sensitive Mutant Of A Virulent Avian Escherichia Coli Isolate, Theodore J. Kottom, Lisa K. Nolan, Michael Robinson, John Brown, Tom Gustad, Shelley M. Horne, Catherine W. Giddings

Lisa K. Nolan

An attempt was made to characterize the mechanism of complement resistance operating in a virulent avian Escherichia coli isolate. Using flow cytometry to detect antibody to C3, we found that there was significantly more antibody bound to a complement-sensitive mutant of this wild type than to the parent organism, suggesting that more C3 subunits were bound to the wild type. Neither the wild type nor the mutant degraded C3. Further, the mutant was phagocytosed to a significantly greater degree than the wild type by cultured phagocytes in the presence of C5-deficient serum. These data suggest that the wild type is …


A Highly Adherent Phenotype Associated With Virulent Bvg+-Phase Swine Isolates Of Bordetella Bronchiseptica Grown Under Modulating Conditions, Karen B. Register, Mark R. Ackermann Dec 1997

A Highly Adherent Phenotype Associated With Virulent Bvg+-Phase Swine Isolates Of Bordetella Bronchiseptica Grown Under Modulating Conditions, Karen B. Register, Mark R. Ackermann

Mark R. Ackermann

The ability of Bvg(-)-phase and Bvg(+)-phase Bordetella bronchiseptica swine isolates, grown under modulating or nonmodulating conditions, to adhere to swine ciliated nasal epithelial cells was determined. When virulent strains were cultivated at 37 degrees C in the Bvg+ phase, numerous adherent bacteria (approximately eight per cell, depending on the strain used) were observed. However, when such strains were grown under modulating conditions (23 degrees C), a significant increase in the level of attachment was seen, suggesting that B. bronchiseptica produces a Bvg-repressed adhesin under these conditions. bvg mutant strains, including an isogenic bvgS mutant, adhered minimally. Western blots indicated that …


Update - December 1997, Loma Linda University Center For Christian Bioethics Dec 1997

Update - December 1997, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- "Spirituality and Ethics in Patient Care"
-- Mind Manipulation: A Christian Ethical Analysis
-- Hobergs, Silk Hose, and Hypnosis


A Dichotomous Role For Nitric Oxide During Acute Toxoplasma Gondii Infection In Mice, Imtiaz A. Khan, Joseph D. Schwartzman, Tadashi Matsuura, Lloyd H. Kasper Dec 1997

A Dichotomous Role For Nitric Oxide During Acute Toxoplasma Gondii Infection In Mice, Imtiaz A. Khan, Joseph D. Schwartzman, Tadashi Matsuura, Lloyd H. Kasper

Dartmouth Scholarship

Production of nitric oxide by macrophages is believed to be an important microbicidal mechanism for a variety of intracellular pathogens, including Toxoplasma gondii. Mice with a targeted disruption of the inducible nitric oxide synthase gene (iNOS) were infected orally with T. gondii tissue cysts. Time to death was prolonged compared with parental controls. Histologic analysis of tissue from infected mice showed scattered small foci of inflammation with parasites in various tissues of iNOS−/− mice, whereas tissue from the parental C57BL/6 mice had more extensive tissue inflammation with few visible parasites. In particular, extensive ulceration and necrosis of distal small …


Direct Demonstration Of Retroviral Recombination In A Rhesus Monkey, Dawn P. Wooley, Randall A. Smith, Susan Czajak, Ronald C. Desrosiers Dec 1997

Direct Demonstration Of Retroviral Recombination In A Rhesus Monkey, Dawn P. Wooley, Randall A. Smith, Susan Czajak, Ronald C. Desrosiers

Neuroscience, Cell Biology & Physiology Faculty Publications

Recombination may be an important mechanism for increasing variation in retroviral populations. Retroviral recombination has been demonstrated in tissue culture systems by artificially creating doubly infected cells. Evidence for retroviral recombination in vivo is indirect and is based principally on the identification of apparently mosaic human immunodeficiency virus type 1 genomes from phylogenetic analyses of viral sequences. We infected a rhesus monkey with two different molecularly cloned strains of simian immunodeficiency virus. One strain of virus had a deletion in vpx and vpr, and the other strain had a deletion in nef. Each strain on its own induced low virus …


The Kinetic Assessment Of Sit-To-Stand In Stroke Patients And Its Relationship To Fall, Pao-Tsai Cheng, Shu-Hsia Wu, Mei-Yun Liaw, Pay-Shin Lin, May-Kuen Wong, Hsieh-Ching Chen, Fuk-Tan Tang Dec 1997

The Kinetic Assessment Of Sit-To-Stand In Stroke Patients And Its Relationship To Fall, Pao-Tsai Cheng, Shu-Hsia Wu, Mei-Yun Liaw, Pay-Shin Lin, May-Kuen Wong, Hsieh-Ching Chen, Fuk-Tan Tang

Rehabilitation Practice and Science

Fall has been reported as a major cause of morbidity, hospitalization and mortality of older people. Stroke patients are more prone to fall than non-stroke subjects, because of the pathological conditions inposing upon the physiological aging process. Since fall is so frequent, fall prevention strategies should therefore be developed and included in rehabilitation programs.Falls are associated with many physical and environmental factors. Excluding tripping, many of the falls in stroke patients occurred during the patients changing their positions, such as standing up, sitting down or initiation of steps. Therefore, the purpose of this study is focus on the kinetic analysis …


Lower Limb Length Discrepancy Caused By Lumbar Epidural Lipomatosis-- A Casereport And Review Of Literature, Mei-Hui Kuo, Chau-Peng Leong Dec 1997

Lower Limb Length Discrepancy Caused By Lumbar Epidural Lipomatosis-- A Casereport And Review Of Literature, Mei-Hui Kuo, Chau-Peng Leong

Rehabilitation Practice and Science

Epidural lipomatosis is resulted from abnormal accumulation of unencapsulated fat in the epidural space. A case with idiopathic spinal lipomatosis is commonly seen in the following situations: steroid treatment, endocrinopathy, and obesity. Interestingly, a young male without the previous three conditions developed idiopathic spinal epidural lipomatosis. He was observed with lower limb length discrepancy and functional scoliosis.This patient was diagnosed by the method of magnetic resonance imaging and later received a variety of treatments according to his symptoms. Since there was no progressive neurological deficit, his problem of functional scoliosis was corrected by elevating his left heel by 2 cm. …


Narrative Development In Late Talkers: Early School Age, Rhea Paul, Rita Hernandez, Lisa Taylor, Karen Johnson Dec 1997

Narrative Development In Late Talkers: Early School Age, Rhea Paul, Rita Hernandez, Lisa Taylor, Karen Johnson

Communication Disorders Faculty Publications

Children with slow expressive language development (SELD) as toddlers and a control group of children with normal language development (NL) were followed to early school age. Children with SELD were, at that point, subdivided into two groups: those who had moved within the normal range of expressive language (the History of Expressive Language Delay [HELD] subgroup); and those who continued to score below the normal range in expressive language at school age (the Expressive Language Delay [ELD] subgroup). During their kindergarten, first, and second grade years, they were administered a narrative generation task. Narratives were analyzed for MLU, lexical diversity, …


Predicting Respiratory Status In Patients With Duchenne Muscular Dystrophy, Rong-Bin Hong, Tyng-Guey Wang, Chih-Whei Lu, Jin-Shin Lai, I-Nan Lien Dec 1997

Predicting Respiratory Status In Patients With Duchenne Muscular Dystrophy, Rong-Bin Hong, Tyng-Guey Wang, Chih-Whei Lu, Jin-Shin Lai, I-Nan Lien

Rehabilitation Practice and Science

The life expectancy of individuals with untreated Duchenne muscular dystrophy(DMD) is around 18-19 years. The cause of their death is mostly from respiratory complications. Early detection of respiratory function will provide the opportunity of early management and prolong their life span.This study included 30 patients with DMD in a period of three years and took a cross-section design. All the data were obtained by telephone interview with the patients or their family. Nineteen of 30 patients accepted functional evaluation in Brooke’s grading scale and pulmonary function test(PFT). Ten of these 19 patients received nocturnal breathing monitor including O2 saturation and …


A Cytochemical Evaluation Of Blood-Brain Barrier Sodium, Potassium- And Calcium-Adenosine Triphosphatase Polarity, Panya Steve Manoonkitiwongsa Dec 1997

A Cytochemical Evaluation Of Blood-Brain Barrier Sodium, Potassium- And Calcium-Adenosine Triphosphatase Polarity, Panya Steve Manoonkitiwongsa

Loma Linda University Electronic Theses, Dissertations & Projects

The blood-brain barrier (BBB) is formed by cerebral vascular endothelial cells. Brain ion and fluid homeotasis essential for proper neural functioning is due to the BBB. Sodium-potassium and calcium-activated adenosine triphosphatase (Na+, K+-ATPase and Ca2+-ATPase) serve as one of the main mechanisms controlling brain Na+, K+, and Ca2+ concentrations. The present accepted concept is that both of these enzymes are localized to the abluminal plasma membrane of endothelial cells although there have been contrary results from some studies. Because of these discrepancies, further work was needed. Various cytochemical procedures …


Mutations In Yeast Proliferating Cell Nuclear Antigen Define Distinct Sites For Interaction With Dna Polymerase Δ And Dna Polymerase Ε, Joel C. Eissenberg, L. Rao Ayyagari, Xavier V. Gomes, Peter M.J. Burgers Dec 1997

Mutations In Yeast Proliferating Cell Nuclear Antigen Define Distinct Sites For Interaction With Dna Polymerase Δ And Dna Polymerase Ε, Joel C. Eissenberg, L. Rao Ayyagari, Xavier V. Gomes, Peter M.J. Burgers

Faculty Scholarship

The importance of the interdomain connector loop and of the carboxy-terminal domain of Saccharomyces cerevisiae proliferating cell nuclear antigen (PCNA) for functional interaction with DNA polymerases delta (Poldelta) and epsilon (Pol epsilon) was investigated by site-directed mutagenesis. Two alleles, pol30-79 (IL126,128AA) in the interdomain connector loop and pol30-90 (PK252,253AA) near the carboxy terminus, caused growth defects and elevated sensitivity to DNA-damaging agents. These two mutants also had elevated rates of spontaneous mutations. The mutator phenotype of pol30-90 was due to partially defective mismatch repair in the mutant. In vitro, the mutant PCNAs showed defects in DNA synthesis. Interestingly, the pol30-79 …


Diabetes And Exercise: The Role Of The Athletic Trainer, Carolyn C. Jimenez Dec 1997

Diabetes And Exercise: The Role Of The Athletic Trainer, Carolyn C. Jimenez

Sports Medicine Faculty Publications

No abstract provided.


Medical Care And Rehabilitation Services Providing To Children With Cerebral Palsy In Northern Taiwan, Hua-Fang Liao, Shwu-Chong Wu, Suh-Fang Jeng, Pen-Jung Wong, Su-Ching Lee, Wen-Po Chow Dec 1997

Medical Care And Rehabilitation Services Providing To Children With Cerebral Palsy In Northern Taiwan, Hua-Fang Liao, Shwu-Chong Wu, Suh-Fang Jeng, Pen-Jung Wong, Su-Ching Lee, Wen-Po Chow

Rehabilitation Practice and Science

The condition of medical and rehabilitation services for children with cerebal palsy(CP)in Taiwan has rarely been investigated. Such information is crucial for the health services planning. To understand the current status of medical and rehabilitation cares of CP children and related influencing factors, we sent 2435 copies of questionnaires to the main caregivers of possible CP children in the northern Taiwan. Six hundred and eighty-nine copies (28%) were returned. Four hundred and twenty-six copies were of CP children younger than 18 years of age(17.5%). Their data were analyzed for this report. In 6-month period prior to this investigation, three hundred …


Short Communication: Definitively Diagnosed Cases Of Paratuberculosis In Imported And Locally Produced Brahman Cows In Thailanf, Monoya Ekgatat, Masaharu Kanameda, Surapong Wongkashemjit, Banchon Apiwatanakorn, Tipa Tanticharoenyos, Pipol Sooksaithaichana, Wassana Seangsuwan Dec 1997

Short Communication: Definitively Diagnosed Cases Of Paratuberculosis In Imported And Locally Produced Brahman Cows In Thailanf, Monoya Ekgatat, Masaharu Kanameda, Surapong Wongkashemjit, Banchon Apiwatanakorn, Tipa Tanticharoenyos, Pipol Sooksaithaichana, Wassana Seangsuwan

The Thai Journal of Veterinary Medicine

No abstract provided.


The Effects Of Animal Assisted Therapy When Used As An Adjunct To Occupational Therapy In The Rehabilitation Of Persons Who Have Had Cerebral Vascular Accidents, Alice Arlene Briggs Dec 1997

The Effects Of Animal Assisted Therapy When Used As An Adjunct To Occupational Therapy In The Rehabilitation Of Persons Who Have Had Cerebral Vascular Accidents, Alice Arlene Briggs

Masters Theses

Occupational therapists can use animals to assist their clients in achieving goals in treatment. Most often dogs are used as they are more easily trained. The dog may fetch a ball thrown by the client or stand still and allow the client to brush it. These activities with the animal increase the client's range of motion, endurance and strength. Dogs as well as other animals are used in various ways to elicit the desired response from the client. No studies were found in the literature that examined the use of animals as adjuncts to, or as modalities in occupational therapy …


Locus Of Control, Activity Level, And Living Situation Among The Elderly, Jennifer L. Birchenough Dec 1997

Locus Of Control, Activity Level, And Living Situation Among The Elderly, Jennifer L. Birchenough

Masters Theses

The focus of this study was to investigate the relationships among locus of control, activity level, and living situation in the elderly. The participants in this study consisted of 62 elderly individuals who resided in one of three living situations: (1) independent living, (2) assisted living, and (3) comprehensive care centers. All participants were screened for cognitive status using the Mini-Mental State Assessment (Folstein, M., Folstein, S., & McHugh, 1975). Individuals who scored in the normal range then completed a Locus of Control Scale (Rotter, 1966) and the Index of Occupational Behavior (Gregory, 1983) to address the meaningfulness of, and …


Cultural Considerations In Clinical Reasoning: An Occupational Therapy Case Study, Sandra M. Winter Dec 1997

Cultural Considerations In Clinical Reasoning: An Occupational Therapy Case Study, Sandra M. Winter

Masters Theses

This study looked at an occupational therapist's work with clients from varied cultural backgrounds. Qualitative research strategies and a phenomenological approach were used to gather data through interviews with a single respondent and observation of treatment. This methodology was used to examine the process utilized to acquire cultural knowledge and integrate that knowledge into treatment planning. Research focused on: (a) how the cultural background of a client influenced an occupational therapist as she planned and implemented treatment, (b) how the treatment process was influenced by cultural differences between the therapist and the client, and (c) how training or education helped …


A Comparison Of Listener And Speaker Perception Of Stuttering Events, Anne Jocelyn Schagen Dec 1997

A Comparison Of Listener And Speaker Perception Of Stuttering Events, Anne Jocelyn Schagen

Dissertations and Theses

Stuttering identification, measurement, research, and treatment have for many years had their basis in listener judgment of stuttering, but the covert aspects of stuttering are not behaviorally observable, and inter-rater reliability has repeatedly been shown to be low. Perkins (1990) has emphasized the importance of consulting the speaker for the most reliable perspective on stuttering identification. The question raised in this study is whether there is a significant correlation between stuttering identification based upon internal perception by a speaker who stutters, and identification based upon external perception of listeners, with points of inter-rater disagreement removed. Six adult males, aged 18 …


The Sensitivity Of Fluorescent Rabies Antibody Testing On Samples Taken From Brain Stem, Cerebellum, Cerebrum And Hippocampus, Veera Tepsumethanon, Boonlert Lumlertdacha, Channarong Mitmoonpitak Dec 1997

The Sensitivity Of Fluorescent Rabies Antibody Testing On Samples Taken From Brain Stem, Cerebellum, Cerebrum And Hippocampus, Veera Tepsumethanon, Boonlert Lumlertdacha, Channarong Mitmoonpitak

The Thai Journal of Veterinary Medicine

A review was carried out on 2,689 brains from animals that were found to be positive for rabies virus by a fluorescent antibody test (FAT) and mouse inoculation test (MIT). Samples were taken from the brain stem, cerebellum, cerebrum and hippocampus of each animal. FAT sensitivity was found to be 99.59, 99.29, 98.88 and 98.74 percent for each of the different sampling sites. It was concluded that the brain stem is the best site for routine rabies FAT diagnosis.