Dose-Dependent Effects Of Salmon Calcitonin On Bone Turnover In Ovariectomized Rats., Beatrice H. Owens

Electronic Theses and Dissertations

In the United States, osteoporosis results in about 1.5 million annual fractures, costing approximately $15 billion. Calcitonin is safe and effective in slowing osteoporotic bone loss, but its effect is transient. The current studies were designed to explore the dose-dependent effects of salmon calcitonin on bone turnover in ovariectomized rats and to determine if the decrease in therapeutic effectiveness of calcitonin demonstrated over time with higher doses is due to oversuppression of bone turnover. Doses of 5, 15, & 50 IU/kg BW/day of calcitonin were compared to placebo in 12-week-old ovariectomized and sham-ovariectomized Sprague-Dawley rats for 24 weeks. The spinal …

Nursing Students' Self-Efficacy And Attitude: Examining The Influence Ofthe Omaha System In Nurse Managed Centers, Cherie Mooy

Master's Projects

Self-efficacy, or confidence, as an outcome behavior has been identified as influencing nursing job satisfaction and retention. Clinical learning environments and teaching strategies that build and support perceived self-efficacy are critical aspects of preparing new nurses for their entry and continuing role as professional nurses in today's information-intensive data-management healthcare environment. The purpose of this pre-test post-test study is to measure, using the C-scale (Grundy, 1992), nursing students' self-efficacy to perform patient assessment in Nurse Managed Centers (NMC) after one semester of using the Omaha System documentation framework. Nursing students' attitudes of preparation for using Standardized Nursing Languages (SNL) in …

Bad Is A Central Player In Cell Death And Cell Cycle Regulation In Breast Cancer Cells, Romaine Ingrid Fernando

Doctoral Dissertations

BAD is a Central Player in Cell Death and Cell Cycle Regulation in Breast Cancer Cells

The estrogen, 17-b estradiol (E2) can stimulate proliferation or induce differentiation or death depending on the cell context. In MCF 7 cells, an estrogen receptor (ER) positive human breast cancer cell line, E₂ has been shown to stimulate cell proliferation and may have an anti-apoptotic effect. E₂ rapidly activates mitogen activated protein kinases (MAPKs) in mammalian cells in an ER dependent fashion. The mechanisms underlying and the physiological significance of the signaling through MAPK remain to be determined. This signal pathway may …

The Potential Role Of Ledgf/P75 In Prostate Cancer, Tracy Ruth Daniels

Loma Linda University Electronic Theses, Dissertations & Projects

The serum autoantibody repertoire from cancer patients is currently being exploited for the identification of tumor associated antigens (TAA) and the design of TAA arrays. Such arrays would facilitate autoantibody profiling and potentially aid in the serological diagnosis and prognosis of tumors. The goal of this study was to identify and characterize prostate-specific TAA. We observed that while the general frequency and titers of autoantibodies in PCa patients were relatively similar to those in matched controls, significant differences could be detected between the two groups in the autoantibody response to the lens epithelial-derived growth factor p75 (LEDGF/p75). LEDGF/p75 is a …

Demographics And Perceptions Of Work Environment For Registered Nurses, Pamela Brotherton Sedano

Master's Projects

Registered nurses (RNs) are the lifeblood of hospitals. Therefore, retaining skilled nurses is necessary to insure the viability of these institutions. A two-year longitudinal, non-experimental research study utilized a descriptive design to compare the perceptions of RNs who remained on their units to those who left or changed units over a two-year time period. The purpose of this study was to ascertain whether there was a statistically significant difference between these two groups. Results in several areas indicate that further evaluation is necessary by nurse managers and administration. This information could help retain RNs as well as attract qualified nurses …

The Influence Of Performance Success, Skill Level, And Gender On The Causal Attributions Of Recreational Golfers, Kevin W. Mchenry

Graduate Theses

The purpose of this study was to examine the effect of performance success, skill level, and gender on the causal attributions made by recreational golfers. Skill level was determined by handicap, and performance success was the golfer’s estimation of whether the particular round of golf was successful or unsuccessful. It was hypothesized that the causal attributions that recreational golfers made would be more internal, stable, and personally controllable after a successful performance than after an unsuccessful performance. Male and female golfers (N=101), from age 19 to 73, with an average age of 39, playing recreationally completed the Causal Dimension Scale-ll …

Folk Healing In The Tradition Of The Fidencista Movement, Katherine Brittain

Theses and Dissertations - UTB/UTPA

The Fidencista Movement is a religion in process . Like in many other medico-religions whose primary ministry is healing, women hold the highest positions of authority. The shamanic channeling of the spirit of the folk saint, Niño Fidencio , plies Fidencistas' belief in the spirit world and ameliorates physical and emotional healing. Fidencistas are concentrated in the Texas/Mexico borderland region where they are facing a passing of traditionalism, the social matrix in which folk healing thrives. However, the signature of the Movement, the penitential trek up the Vía de Dolores in Espinazo, is a cohering bi-annual ritual that fortifies devotion …

The Effects Of Nursing Back Rub On Pain And Wound Cytokines And The Relationship Between Pre-Cabg Mood And Post-Cabg Wound Cytokines, Kathlene D. Smith

Doctoral Dissertations

This study, guided by psychoneuroimmunology theory, examined the effects of a 10-minute nursing back rub in 20 coronary artery bypass graft (CABG) patients on pain and four proinflammatory wound cytokines (IL-1β, IL-6, IL-8, and TNF-α). It also examined the relationships between the Profile of Mood States (POMS) and the proinflammatory cytokines. A control group (n = 8) received time with the researcher, and an experimental group (n = 12) received a slow stroke effleurage back rub. All participants initially completed the POMS and after surgery, wound fluid was collected from the mediastinal chest tube before and after the intervention. Analysis …

Childhood Experiences Of Appalachian Women Who Have Experienced Intimate Partner Violence During Adulthood., Amy L. Reeves

Electronic Theses and Dissertations

Recent national surveys in the United States estimate one in five females will experience abuse by an intimate partner during her lifetime. Previous quantitative research linked childhood victimization to repeated victimization in adult relationships. This qualitative study explored the lived experiences of childhood in eight female victims of intimate partner violence who were born and reared in southern Appalachia. Interviews were analyzed using a descriptive-interpretative phenomenological method, as described by Van Manen. The three essential themes from childhood were identified as: living 'as if' an orphan; surviving in chaos; and, manifesting a devalued self. These themes were congruent with findings …

A Closer Look At Development Of Self-Awareness And Compensatory Strategy Use In Adults With Traumatic Brain Injury, Melissa A. Byrne

Masters Theses

My study investigates the development of self-awareness and use of compensatory strategies in eight adults with traumatic brain injuries using the Awareness Questionnaire (AQ) and three additional questions of descriptive nature. This study also examines whether or not the severity of brain injury (mild, moderate, severe) impacts the development of self-awareness. In addition, the spouses' perceptions of client awareness are compared to the relatives' to determine existence of potential variance.

Results indicate that while there is no significant difference in self-awareness_ between the mild and moderate groups, the severe group significantly varies from both the mild and moderate groups. Also, …

A Study Of Pediatric Heart Transplant Patients In Relationship To Post Transplant Coronary Artery Disease, Mark Randall

Loma Linda University Electronic Theses, Dissertations & Projects

Post transplant coronary artery disease influences short and long-term survival of pediatric heart transplant recipients. Associated cardiovascular disease risk factors among non-heart transplant adult and pediatric heart populations for development of coronary artery disease have been documented. Little is known about these typical cardiovascular disease risk factors as well as other possible risk factors in the development of post transplant coronary artery disease. Objective: The purpose of this research was to examine children/adolescents (n=194), 5-18 years old, at least one-year post heart transplant. This study also investigated if there were physiological and psychological/behavioral differences between recipients with (n = 28) …

Benefits Of A Postgraduate Education: The Physician Assistants' Perspective, Jamie Cotter

Theses and Graduate Projects

Background: This study was completed to better understand the use of postgraduate education in the physician assistant profession. This research project gathered information to better understand how physician assistants have utilized postgraduate education in their careers. The potential benefits of a postgraduate education were also examined from the perspective of the physician assistant. The overall goal was to determine the benefits of a PA postgraduate education. Methods: For this research project, a survey was completed by practicing physician assistants who attended the Minnesota Academy of Physician Assistants (MAPA) Conference/North Central Regional Meeting that was held on March 27-29, 2003. This …

The Efficacy Of A School-Based Support Group On Adolescent Self-Esteem And Social Support, Julia Ann Smith Phd

Dissertations

Adolescents are faced with daily obstacles that affect their ability to progress into adulthood successfully. Rising divorce rates and subsequent single parenting, adolescent pregnancy, drug and alcohol abuse, violence, and lack of parental involvement represent only a few of the many issues teens confront. School nurses are on the front lines, attempting to educate youth against an alarming rise in personal and social controversies that impede their ability to come to school ready to learn. As part of the educational team, school nurses are in a prime position to develop and integrate intervention strategies aimed at assisting adolescents during this …

Factors That Contribute To Nursing Job Satisfaction At Valley Hospital, Christopher Jones

UNLV Theses, Dissertations, Professional Papers, and Capstones

The United States is in the midst of a nursing shortage and it is expected to get even worse in the coming years due to several trends. These trends include the aging of the workforce where many nurses will be retiring in the next few years, the low enrollment in nursing schools, nurses leaving the profession for other fields of work and the lack of interest that many people are showing towards a career in nursing.

The Role Of Dairy Products In The Calcium Intake Of Suburban Adolescents, Simie Bredeweg-Dejager

Masters Theses

The purpose of this study was to examine consumption of dairy products by suburban adolescents. This was a secondary analysis of data from a questionnaire administered in late fall of 2003. There were 255 adolescents who completed the questionnaire. Data were examined to estimate calcium intake from dairy products.

There was a significant difference in the amount of calcium adolescents consume from cheese, compared to that supplied by milk (t = -8.502, p = .000). Further analyzing by gender, there was a significant difference between boys and girls intake of milk and cheese. No significant difference was found between boys …

Pediatric Obesity: Intervention Outcomes, Kristy Anne Kuehfuss

Loma Linda University Electronic Theses, Dissertations & Projects

Childhood obesity is a national epidemic with serious medical and psychological implications. Almost one-fourth of children in the United States are overweight. Children do not typically grow out of obesity and without intervention the majority of overweight children become overweight adults. Further, childhood obesity results in numerous chronic medical conditions. Thus, the prevention and treatment of childhood obesity are paramount to the avoidance of resultant physical and psychological risk factors. Loma Linda University’s Growing Fit Program seeks to serve the critical and urgent needs of the ever-increasing population of obese children with a multi-disciplinary approach to pediatric weight management. Evaluating …

Coping Patterns Among Perpetrators Of Child Sexual Abuse, Henry Adolphus Beck

Loma Linda University Electronic Theses, Dissertations & Projects

This study examined the coping and religious coping strategies used by child sexual abuse (CSA) perpetrators. It was hypothesized that (1) Perpetrators of incestuous CSA would show greater use of Emotion-Oriented coping than perpetrators of non-incestuous CSA, (2) perpetrators of non-incestuous CSA would show greater use of Task-Oriented coping than perpetrators of incestuous CSA (3) Perpetrators of incestuous CSA would show greater use of Avoidance-Oriented coping than perpetrators of non-incestuous CSA, and (4) there would be a difference in the use of positive and negative religious coping between groups of incestuous and non-incestuous CSA perpetrators. Participants completed the Coping Inventory …

Prevalence Of Degenerative Joint Disease In A Pre-Orthodontic Adolescent Sample, Marie Mansour

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this research was to determine a prevalence of degenerative joint disease in our pre-orthodontic adolescent patients age ten through seventeen. The prevalence was assessed according to gender. Severity of DJD was established for each patient and a "red flag" for diagnosis was identified. The purpose was also to establish norms for joint space for patients with and without degenerative joint disease. Correlations to distal condyle position and angle classification were described. 123 consecutive patients, 77 female and 46 male T1 NewTom records were reviewed. Severity of DJD was classified according to none, mild, moderate, and severe. Sagittal …

Cone Beam Ct And Digital Radiography. A Comparative Study Of P/A Cephalometrics., Michael John Erickson

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to determine if Rickett's posterio-anterior (P/A) cephalogram measurements could be obtained from Cone Beam Computerized Tomographic (CBCT) images taken on the NewTom QR-DVT 9000™.

Fifteen frontal cephalometric radiographs were chosen for good image quality, with no regard for patient age or gender. Each cephalogram was traced three times by the same operator using ZeroBase™ software. Landmarks were located and measured according to the Rickett's frontal analysis technique. Methods were devised for obtaining analogous measurements using CBCT images on the same group of patients.

Measurements obtained using CBCT correlated well with those obtained using the …

Cultural Value Orientations, Attributions, And Breast Cancer Screening Behaviors, Patricia M. Flynn

Loma Linda University Electronic Theses, Dissertations & Projects

Discrepancies in breast cancer screening behavior exist among various ethnic groups in the United States (Jacobs & Lauderdale, 2001), with Latino American women reporting particularly low screening rates in comparison to Anglo American women (ACS, 2002). Research indicates that behavior is in part influenced by aspects of culture and relevant psychological processes (Betancourt & Lopez, 1993; Betancourt & Fuentes, 2001). This study was designed to investigate the relations among cultural values, attributional processes, and breast cancer screening behavior among Anglo and Latino women. This study also investigated the influence of acculturation among Latino women in relation to the other study …

Psychological Factors Associated With Anticipatory Nausea And Vomiting, Melinda L. Nielsen

Loma Linda University Electronic Theses, Dissertations & Projects

Many cancer patients experience adverse chemotherapy-related side effects. The present study examined the relationships among disease variables (i.e. stage of cancer, type of breast cancer), medical treatment variables (i.e. toxicity of chemotherapy regimen, strength of antiemetic treatment), psychological variables (i.e. health locus of control, anxiety sensitivity, desire for control, coping strategies), and anticipatory nausea and vomiting in women with breast cancer. One hundred women with breast cancer completed the Multidimensional Health Locus of Control Scale - Form C, the Anxiety Sensitivity Index, the Krantz Health Opinion Survey, the Coping Inventory for Stressful Situations, and the Morrow Assessment of Nausea and …

Facing Uncertainty, Proceeding With Caution, Living With Joy: Women With Multiple Sclerosis And The Motherhood Decision, Anne L. Van Acker

MALS Final Projects, 1995-2019

Multiple sclerosis is a degenerative neurological disorder, affecting approximately 250,000-350,000 persons in the United States. Women are diagnosed twice as frequently as men, with the majority of those diagnoses occurring during their childbearing (typically between the ages of 20 and 40) years. For women with multiple sclerosis, the decision to bear children is complicated by numerous factors. First, conventional cultural images of motherhood rarely acknowledge women with disability of any kind as "fit" mothers. For a disabled woman to pursue motherhood often means confronting predominant ideals and frequently having to justify her decision. Second, multiple sclerosis has proven to be …

How Much Weight Is Too Much For Manual Lifting : Determining A Weight Limit Guideline For Team-Effort Lifting Tasks, Piyush G. Chapla

Theses

Manual material handling is the primary cause of musculoskeletal injuries, which includes injuries related to lower back, at the workplaces in the U.S. Of all the manual material handling tasks, lifting has been the leading contributor to lower back injuries. These injuries may be induced by several risk factors associated with lifting tasks, weight of the object being lifted being one of them.

Weight limit guidelines have been developed by various groups recommending the weights that workers can lift safely without sustaining injuries. However, these guidelines are aimed to serve individual lifting tasks. Even though team lifting is a common …

Development And Assessment Of An Innovative Video To Introduce Concepts Of Adherence In Soweto, South Africa, Ilene Wong

Yale Medicine Thesis Digital Library

ISSUES: The widening availability of antiretroviral therapy but dearth of medication taking experience among rural South Africans has raised concerns about adequate adherence to these medications. Interventions to improve adherence have been limited in development and evaluation and are often not culturally appropriate to patients in resource poor settings. It is hypothesized that a culturally-sensitive audio-visual patient education program may be of significant use in increasing patient understanding of concepts of resistance and medication taking skills, particularly in areas with low literacy rates. METHODS: After focus groups with health care providers and HIV-positive adherence counselors, a 15 minute educational video …

Early Speech And Language Development: A Comparison Of Typically Developing Children To Children With Cleft Palate., Holly Jannice Mcgahey

Electronic Theses and Dissertations

Previous research has shown that parent implemented intervention is effective in increasing the speech and language development of children with cleft lip and palate. To further determine the efficacy of this intervention, this study compared the speech and language development of children with CLP, who received parent implemented intervention, with a group of younger, typically developing children, matched for vocabulary size. This study also evaluated the language differences between the mothers of both groups of children. Speech and language assessments were administered to the typically developing children and their mothers at two times to mirror the time of assessment for …

Nongenomic Effects Of Estrogens On Epithelial Chloride Secretion., Sabyasachi Moulik

Electronic Theses and Dissertations

The human colonic cell line T84, a model for studying epithelial chloride secretion and cystic fibrosis chloride channel (CFTR) function, was used to investigate the regulatory role of estrogens in transepithelial ion transport. Estrogens and other steroid hormones do not stimulate chloride secretion by themselves. However, 17 β-estradiol (17β-E2) rapidly (within seconds to minutes) potentiates carbachol- and thapsigargin-stimulated chloride secretion measured as short circuit current in voltage-clamped T84 monolayer cultures. The cholinergic agonist carbachol and the SR Ca²⁺ ATPase inhibitor thapsigargin stimulate chloride secretion by elevating intracellular calcium. 17α-estradiol, a stereoisomer that does not activate nuclear estrogen receptors, is …

Responses Of Flight Nurses To Catastrophic Events, Gene L. Olsen

Masters Theses

The purpose of this study was to examine for the presence of symptoms associated with post-traumatic stress disorder (PTSD) in a sample of flight nurses. Also examined were the coping mechanisms used by the sample to ameliorate the stressors associated with performing the role of the flight nurse, as well as the relationship between the symptoms and the coping mechanisms identified by the sample. Data were collected by questionnaires sent to a randomly selected national sample of 350 flight nurses who belong to the Air and Surface Transport Nurses Association.

Of the 101 participants, intrusion was found to be most …

Examining The Meaning And Experience Of Self-Determination And Its Impact On Quality Of Life For Individuals With Cognitive Disabilities, Carol Marie Sundberg

Dissertations

There is a national agenda for advancing self-determination for persons with disabilities. Broadly defined, self-determination means having control over ones own life. The purpose of this research was to gain a better understanding of self-determination and its effect on the quality of life of persons with cognitive disabilities. A qualitative, phenomenological approach was selected. Ten individuals from a community mental health system in southwest Michigan participated in the study. Participants had a developmental disability and were dependent on others for their care. The research combined qualitative interviews with behavioral observations and proxy interviewing, and included the audiotaping of those interviews. …

Self-Efficacy, Metastasis, Treatment, And Demographics As Predictors Of Functional Performance Status Of Adult Colorectal Cancer Patients, Dollie A. Husfeld

Theses and Dissertations - UTB/UTPA

The purpose of this study was to assess self-efficacy as a predictor of functional performance status in order to discover correlations that could be used to improve care of the colorectal cancer patient. Thirty participants were accessed through three outpatient cancer clinics during a two-week period. Data was collected through a demographics questionnaire, the Cancer Behavior Inventory Long Form, and the Karnofsky Performance Scale Index. Stepwise multiple regression was used to identify and relationships between the dependent variable, functional performance status, and the independent variables, self-efficacy, age, gender, residence, treatment, and metastasis ( p = .05). Pearson's correlation showed a …

The Relationship Between Steps Walked Per Day And Body Composition In Postmenopausal Women, Emily Martin Krumm

Masters Theses

The objective of this study was to examine the relationship between pedometer-determined physical activity measured in steps per day and body composition in healthy, postmenopausal women. Ninety-three women (60.9 ± 5.76 years) participated in the study. Subjects made one visit to the laboratory for height, weight, percent body fat, and waist and hip circumference measurements. Subsequently, each subject wore a pedometer for 14 consecutive days to assess average daily steps. Subjects recorded each day’s accumulated step count and reset the pedometer the next morning. Pearson product moment correlations were used to examine the relationship between average steps per day and …