Digital Commons Network^™

Wicked Problems: Depression, Sebastian Wendolowski

English Department: Research for Change - Wicked Problems in Our World

Depression is a disorder that can affect anybody and is the leading cause of disability and disorders in the United States. This year, due to COVID-19, it has hit an all time high, affecting many more people. Suicide rates have been steadily growing across all ages, and this year is at a record high too, showing correlation with depression. There are two types of depression, major depressive disorder and chronic depressive disorder. Diagnosis of depression is typically done physically or through a questionnaire, which is compared into a DSM-5. There are many risk factors for depression and other common mental …

Implementing Nudges For Suicide Prevention In Real-World Environments: Project Inspire Study Protocol, Molly Davis, Courtney Benjamin Wolk, Shari Jager-Hyman, Rinad S Beidas, Jami F Young, Jennifer A Mautone, Alison M Buttenheim, David S Mandell, Kevin G Volpp, Katherine Wislocki, Anne Futterer, Darby Marx, E L Dieckmeyer, Emily M Becker-Haimes

College of Life Sciences Faculty Papers

Background: Suicide is a global health issue. There are a number of evidence-based practices for suicide screening, assessment, and intervention that are not routinely deployed in usual care settings. The goal of this study is to develop and test implementation strategies to facilitate evidence-based suicide screening, assessment, and intervention in two settings where individuals at risk for suicide are especially likely to present: primary care and specialty mental health care. We will leverage methods from behavioral economics, which involves understanding the many factors that influence human decision making, to inform strategy development.

Methods: We will identify key mechanisms that limit …

Dramatic Outcomes In Epilepsy: Depression, Suicide, Injuries, And Mortality, Boulenouar Mesraoua, Dirk Deleu, Al Hail Hassan, Melykian Gayane, Alsheikh Lubna, Musab Abdalhalim Ali, Torbjorn Tomson, Bassel Abou Khalil, J Helen Cross, Ali A Asadi-Pooya

Department of Neurology Faculty Papers

In this narrative review, we will discuss some of the significant risks and dramatic consequences that are associated with epilepsy: depression, suicide, seizure-related injuries, and mortality, both in adults and in children. Considering the high prevalence of depression among people with epilepsy (PWE), routine and periodic screening of all PWE for early detection and appropriate management of depression is recommended. PWE should be screened for suicidal ideation regularly and when needed, patients should be referred for a psychiatric evaluation and treatment. When starting an antiepileptic drug (AED) or switching from one to another AED, patients should be advised to report …

Smartphone Applications Targeting Borderline Personality Disorder Symptoms: A Systematic Review And Meta-Analysis., Gabrielle Ilagan, Evan Iliakis, Chelsey Wilks, Ipsit Vahia, Ipsit Vahia, Lois Choi-Kain, Lois Choi-Kain

Psychology Faculty Works

Background: Smartphone applications could improve symptoms of borderline personality disorder (BPD) in a scalable and resource-efficient manner in the context limited access to specialized care. Objective: This systematic review and meta-analysis aims to evaluate the effectiveness of applications designed as treatment interventions for adults with symptoms such as anger, suicidality, or self-harm that commonly occur in BPD. Data sources: Search terms for BPD symptoms, smartphone applications, and treatment interventions were combined on PubMed, MEDLINE, and PsycINFO from database inception to December 2019. Study selection: Controlled and uncontrolled studies of smartphone interventions for adult participants with symptoms such as anger, suicidality, …

Preferences In Information Processing, Marginalized Identity, And Non-Monogamy: Understanding Factors In Suicide-Related Behavior Among Members Of The Alternative Sexuality Community, Robert J. Cramer, Jennifer Langhinrichsen-Rohling, Andrea R. Kaniuka, Corrine N. Wilsey, Annelise Mennicke, Susan Wright, Erika Montanaro, Jessamyn Bowling, Kristin E. Heron

Psychology Faculty Publications

Suicide-related behavior (SRB) is a mental health disparity experienced by the alternative sexuality community. We assessed mental health, relationship orientation, marginalized identities (i.e., sexual orientation minority, gender minority, racial minority, ethnic minority, and lower education), and preferences in information processing (PIP) as factors differentiating lifetime SRB groups. An online cross-sectional survey study was conducted in 2018. Members of the National Coalition for Sexual Freedom (NCSF; n = 334) took part. Bivariate analyses identified the following SRB risk factors: female and transgender/gender non-binary identity, sexual orientation minority identity, lower education, suicide attempt/death exposure, Need for Affect (NFA) Avoidance, depression, and anxiety. …

An Application Of The Interpersonal Psychological Theory Of Suicide In College-Age Survivors Of Sexual Assault, Ava Katherine Fergerson

Masters Theses & Specialist Projects

Sexual victimization is a pervasive public health concern that disproportionately affects college students and results in severe mental and physical health risks for survivors. Despite low prevalence rates in the general population, a national study found that 33% of survivors of rape reported suicidal ideation, and 13% actually made a suicide attempt (Kilpatrick et al., 1992). Although it is clear that survivors of sexual violence are at increased risk for suicide, knowledge is largely limited to epidemiological studies. Few studies have integrated theories of suicide to understand how and why this population is at such elevated risk for suicidal thoughts …

Genome-Wide Dna Methylation Meta-Analysis In The Brains Of Suicide Completers, Stefanie Policicchio, Sam Washer, Joana Viana, Artemis Latrou, Joe Burrage, Eilis Hannon, Gustavo Turecki, Zachary Kaminsky, Jonathan Mill, Emma L. Dempster, Therese Murphy

Articles

Suicide is the second leading cause of death globally among young people representing a significant global health burden. Although the molecular correlates of suicide remains poorly understood, it has been hypothesised that epigenomic processes may play a role. The objective of this study was to identify suicide-associated DNA methylation changes in the human brain by utilising previously published and unpublished methylomic datasets. We analysed prefrontal cortex (PFC, n = 211) and cerebellum (CER, n = 114) DNA methylation profiles from suicide completers and non-psychiatric, sudden-death controls, meta-analysing data from independent cohorts for each brain region separately. We report evidence for …

Genome-Wide Dna Methylation Meta-Analysis In The Brains Of Suicide Completers, Stefania Policicchio, Sam Washer, Joana Viana, Artemis Iatrou, Joe Burrage, Eilis Hannon, Gustavo Tureki, Zachary Kaminsky, Jonathan Mill, Emma L. Dempster, Therese Murphy

Articles

Suicide is the second leading cause of death globally among young people representing a significant global health burden. Although the molecular correlates of suicide remains poorly understood, it has been hypothesised that epigenomic processes may play a role. The objective of this study was to identify suicide-associated DNA methylation changes in the human brain by utilising previously published and unpublished methylomic datasets. We analysed prefrontal cortex (PFC, n = 211) and cerebellum (CER, n = 114) DNA methylation profiles from suicide completers and non-psychiatric, sudden-death controls, meta-analysing data from independent cohorts for each brain region separately. We report evidence for …

Understanding The Relationship Between Suicide Rates, Exercise, Commute Drive, And Healthcare Provider, Kaitlin Beemiller

Scholarship in Medicine - All Papers

Suicide is the tenth leading cause of death in the United States, with rates that have been rising significantly over the past decade, differing in varying states.1,2 Although there is not a lot known about the specific causes of these trends, recent literature has found a dose-response relationship association between inactivity and poor mental health, self-harm, and suicidal attempt, indicating that physical activity may possess a protective nature.1,4 Further expanding off this research, I wanted to investigate the relationships between rates of access to exercise, long commute drives, and healthcare providers to rates of suicide in 5 different states— to …

The Effects Of Daily Sunlight Levels On Suicide Rates, Amna Amin

Scholarship in Medicine - All Papers

The correlation between sunlight and mental health has been long studied and is even involved in the development of Seasonal Affective Disorder (SAD), with subsequent development of light therapy for affected individuals. This points towards the question of the effects of varying levels of daily sunlight in the United States on rates of suicide – a reflection of the extreme state of suboptimal mental health. I have ventured to study this question, using publicly available data on the daily sunlight levels in various states in the U.S. during each month of the year and the rates of suicide in those …

Analysis Of Personality, Suicide, And Self‐Injury In Emerging Adulthood, Amanda C. La Guardia, Robert J. Cramer, Claire N. Bryson, Kelly Emelianchik-Key

Community & Environmental Health Faculty Publications

Nonsuicidal self‐injury (NSSI) is a maladaptive coping strategy that is of significant clinical concern for behavioral health professionals in college settings. Relationships between NSSI, acquired capability for suicide, interpersonal cognitions, and five‐factor model personality traits were assessed in a survey‐based study that included 192 young adults in a college setting. Results indicated that those with an affirmative suicide attempt history, greater acquired capability for suicide, and elevated neuroticism had an increased likelihood of lifetime NSSI.

A Hard Row To Hoe: Suicide Among Kentucky Farmers, Olivia Eiler

Mahurin Honors College Capstone Experience/Thesis Projects

According to the Centers for Disease Control and Prevention, male farmers die by suicide at nearly twice the rate of the general population. My research focuses on understanding the factors contributing to this trend and identifying potential solutions, with a specific focus on the Commonwealth of Kentucky. I have collected qualitative data through video interviews with political leaders, scholars, and youth who are active in the agriculture community. These individuals have identified several key stressors, including stigma, a lack of healthcare providers in rural areas, financial insecurity, a lack of appreciation from the public, and uncertainty due to decisions made …

A History Of The Law Of Assisted Dying In The United States, Alan Meisel

Articles

The slow growth in the number of states that have enacted legislation to permit what is often referred to as “death with dignity” legislation—and more frequently referred to popularly as “physician assisted suicide” laws—has begun to accelerate in the past few years since the enactment of the first such statute in Oregon in 1994.

Like much other social reform legislation, there is a long history behind it. In this case, the history in the United States dates back at least to the latter part of the nineteenth century. Not until the 1980s, however, did these efforts gain any traction in …