Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Children (7)
- Inflammation (6)
- Oxidative stress (6)
- Psoriasis (5)
- Chronic obstructive pulmonary disease (4)
-
- Reliability (4)
- Ultrasonography (4)
- Validity (4)
- Atherosclerosis (3)
- Body mass index (3)
- Breast cancer (3)
- Child (3)
- Epilepsy (3)
- Gastric cancer (3)
- Intubation (3)
- Prevalence (3)
- Rat (3)
- Rehabilitation (3)
- Rheumatoid arthritis (3)
- Risk factors (3)
- Turkey (3)
- Vitiligo (3)
- Allergic rhinitis (2)
- Alopecia areata (2)
- Amputation (2)
- Anxiety (2)
- Asthma (2)
- Breast (2)
- Brucellosis (2)
- Calcification (2)
Articles 1 - 30 of 253
Full-Text Articles in Entire DC Network
Ischemic Modified Albumin As A New Biomarker In Predicting Oxidative Stress In Alopecia Areata, Hati̇ce Ataş, Müzeyyen Gönül, Yasi̇n Öztürk, Mustafa Kavutçu
Ischemic Modified Albumin As A New Biomarker In Predicting Oxidative Stress In Alopecia Areata, Hati̇ce Ataş, Müzeyyen Gönül, Yasi̇n Öztürk, Mustafa Kavutçu
Turkish Journal of Medical Sciences
Results show that oxidative stress is a pathophysiologic factor for alopecia areata (AA); however, the markers used can be confounding. Thus, we aimed to investigate the role of oxidative stress in the pathogenesis of AA through an evaluation of ischemia-modified albumin (IMA); other markers of the oxidant/antioxidant system, such as SOD, CAT, GSH-ST, and MDA; and contributing clinical risk factors. Materials and methods: The usefulness of IMA as a new marker for oxidative stress was compared with that of other markers and evaluated in patients with AA.Results: The mean serum level of IMA was of higher statistical significance in AA …
Evaluation Of Measles Immunity In Turkey: Is It Still A Threat?, Selda Karaayvaz, Melahat Melek Oğuz, Ufuk Beyazova, Fatma Gülay Korukluoğlu, Yasemi̇n Coşgun, Zeli̇ha Güzelküçük, Fatma Nur Baran Aksakal, Fi̇gen Şahi̇n Dağli
Evaluation Of Measles Immunity In Turkey: Is It Still A Threat?, Selda Karaayvaz, Melahat Melek Oğuz, Ufuk Beyazova, Fatma Gülay Korukluoğlu, Yasemi̇n Coşgun, Zeli̇ha Güzelküçük, Fatma Nur Baran Aksakal, Fi̇gen Şahi̇n Dağli
Turkish Journal of Medical Sciences
Background/aim: Measles is one of the important vaccine-preventable diseases with many complications in childhood. This study presents cross-sectional seroepidemiological data, beginning from neonatal cord blood in infants to children under 6 years of age, about waning of measles antibody and tries to suggest the proper time for measles immunization.Materials and methods: A total of 564 blood samples consisting of neonatal cord blood and samples taken from infants and children at ages of 6, 9, 24-48, and 49-72 months were analyzed for measles seropositivity in a period of 6 months. Results: Measles seropositivity rate was 72.5% in 109 cord blood samples, …
Effects Of Ankaferd Hemostat On Helicobacter Pylori Strains And Antibiotic Resistance, Rafi̇ye Çi̇ftçi̇ler, Ahmet Koluman, İbrahi̇m Celaletti̇n Haznedaroğlu, Nejat Akar
Effects Of Ankaferd Hemostat On Helicobacter Pylori Strains And Antibiotic Resistance, Rafi̇ye Çi̇ftçi̇ler, Ahmet Koluman, İbrahi̇m Celaletti̇n Haznedaroğlu, Nejat Akar
Turkish Journal of Medical Sciences
Background/aim: Ankaferd hemostat (ABS; Ankaferd blood stopper, İstanbul, Turkey) is a folkloric medicinal plant extract. The aim of this study was to determine the effect of Ankaferd hemostat (ABS) on the fate of Helicobacter pylori strains. The study also aims to determine alterations in the antimicrobial resistance of three different H. pylori strains in response to ABS exposure.Materials and methods: H. pylori Strain 1 was obtained from the culture collection ATCC 43504 and passaged three times for viability. Strain 2 was isolated from a gastric ulcer patient and Strain 3 was isolated from a gastritis patient. 1% of ABS was …
Retracted Article: Prevalence And Antimicrobial Susceptibility Pattern Of Toxigenic Clostridium Difficilestrains Isolated In Iran, Maryam Mohammadbeigi, Zahra Safayi Delouyi, Nima Mohammadzadeh, Arash Ala'almohadesin, Keyvan Taheri, Elahe Edalati, Mansour Sedighi, Abed Zahedi Bialvaei
Retracted Article: Prevalence And Antimicrobial Susceptibility Pattern Of Toxigenic Clostridium Difficilestrains Isolated In Iran, Maryam Mohammadbeigi, Zahra Safayi Delouyi, Nima Mohammadzadeh, Arash Ala'almohadesin, Keyvan Taheri, Elahe Edalati, Mansour Sedighi, Abed Zahedi Bialvaei
Turkish Journal of Medical Sciences
No abstract provided.
S1pr2 Deficiency Enhances Neuropathic Pain Induced By Partial Sciatic Nerve Ligation, Qiang Gu, Jin Chao Hou, Xiang Ming Fang
S1pr2 Deficiency Enhances Neuropathic Pain Induced By Partial Sciatic Nerve Ligation, Qiang Gu, Jin Chao Hou, Xiang Ming Fang
Turkish Journal of Medical Sciences
Background/aim: Sphingosine 1-phosphate receptor 2 (S1PR2), a member of the seven-transmembrane receptor family, can be activated by its natural ligand sphingosine 1-phosphate (S1P) to initiate signal transduction and is involved in a wide range of biological effects such as immune cell migration and vascular permeability. Its relationship with neuropathic pain (NP) has not been reported. In this study, the effects of S1PR2 on the development of NP were studied.Materials and methods: We generated a model of NP by partial sciatic nerve ligation (pSNL). The 50% paw withdrawal threshold of the wild-type (WT) group and the S1PR2 deficiency group were measured …
The Results Of Nasopharyngeal Cancer Patients Treated By Simultaneous Integrated Boost Technique And Concomitant Chemotherapy, Mehmet Fai̇k Çeti̇ndağ, Ati̇ye Yilmaz Özsavran, Bülent Yalçin, İclal Çeti̇ndağ, Şeyda Türkölmez, Karabeki̇r Ercan, Di̇nçer Yeğen
The Results Of Nasopharyngeal Cancer Patients Treated By Simultaneous Integrated Boost Technique And Concomitant Chemotherapy, Mehmet Fai̇k Çeti̇ndağ, Ati̇ye Yilmaz Özsavran, Bülent Yalçin, İclal Çeti̇ndağ, Şeyda Türkölmez, Karabeki̇r Ercan, Di̇nçer Yeğen
Turkish Journal of Medical Sciences
Background/aim: To assess the efficacy and side effects of concurrent weekly chemotherapy and radiotherapy with simultaneous integrated boost (SIB) technique for nasopharyngeal cancer (NPC). Materials and methods: A total of 51 consecutive patients with diagnosis of NPC were treated between February 2010 and December 2015. The median dose for PTV70 (range: 60-82) was given in 33 fractions (range: 31-35). Forty-five of the patients received concomitant weekly chemotherapy between 3-7 cycles (median 6). Eleven patients received neoadjuvant and thirty-nine patients received adjuvant chemotherapy. Results: At a median follow-up 43 months (range: 2-76) the estimated 5-year overall survival and disease-free survival were …
Evaluation Of Sarcopenia, Sarcopenic Obesity, And Phase Angle In Geriatric Gastrointestinal Cancer Patients: Before And After Chemotherapy, Derya Hopanci Biçakli, Rüksan Çehreli̇, Ahmet Özveren, Reci̇ Meseri̇, Rüçhan Uslu, Mehmet Uyar, Bülent Karabulut, Selahatti̇n Fehmi̇ Akçi̇çek
Evaluation Of Sarcopenia, Sarcopenic Obesity, And Phase Angle In Geriatric Gastrointestinal Cancer Patients: Before And After Chemotherapy, Derya Hopanci Biçakli, Rüksan Çehreli̇, Ahmet Özveren, Reci̇ Meseri̇, Rüçhan Uslu, Mehmet Uyar, Bülent Karabulut, Selahatti̇n Fehmi̇ Akçi̇çek
Turkish Journal of Medical Sciences
Background/aim: The purpose of this study was to determine sarcopenia, sarcopenic obesity and phase angle (PA) and the influence of chemotherapy (CT) on anthropometric measurements and and the PA in in geriatric patients with gastrointestinal (GI) cancer. Material and methods: The anthropometric measurements, calf circumference (CC), upper midarm circumference (UMAC), and hand grip strength (HGS), have been measured to understand muscle function of 153 patients (mean age of 70.5 ± 5.6 years, 28.8% female, 71.2% male). Sarcopenia and PA measurements have been evaluated by bioelectrical impedance analyses. The same evaluations were checked again after 1 cycle of CT (min: 4, …
Results Of Home-Based Modified Combined Decongestive Therapy In Patients With Lower Extremity Lymphedema, Ali̇s Kostanoğlu, Meltem Ramoğlu, Ethem Güneren
Results Of Home-Based Modified Combined Decongestive Therapy In Patients With Lower Extremity Lymphedema, Ali̇s Kostanoğlu, Meltem Ramoğlu, Ethem Güneren
Turkish Journal of Medical Sciences
Background/aim: The aim of this study is to present the results of modified combined decongestive therapy (CDT) in patients with lower extremity lymphedema (LEL). Materials and methods: We retrospectively reviewed 95 patients aged 55.84 ± 15.70 years who had been diagnosed with LEL between May 2015 and May 2017. The patients were treated for 4 weeks with modified CDT, including self-manual lymphatic drainage, self-bandaging, decongestive exercises, and skin care.Results: The mean reduction amounts of edema volume before and after treatment were 296.05, 784.92, and 1038.50 mL for stages 1, 2, and 3 respectively (P = 0.001). There were significant differences …
Diagnostic Value Of 3d Power Doppler Ultrasound In The Characterization Of Thyroid Nodules, Ayşegül Cansu, Emi̇n Ayan, Si̇bel Kul, İlker Eyüboglu, Şükrü Oğuz, Sevdegül Mungan
Diagnostic Value Of 3d Power Doppler Ultrasound In The Characterization Of Thyroid Nodules, Ayşegül Cansu, Emi̇n Ayan, Si̇bel Kul, İlker Eyüboglu, Şükrü Oğuz, Sevdegül Mungan
Turkish Journal of Medical Sciences
Background/aim: This study aimed to evaluate the diagnostic value of vascular indices obtained using 3D power Doppler ultrasound (3D PDUS) in differentiation of benign and malignant thyroid nodules.Materials and methods: Sixty-seven patients (56 female, 11 male, mean age 44.6) with 81 thyroid nodules exhibiting mixed (peripheral and central) vascularization patterns, with the largest diameter between 10 and 30 mm, were prospectively evaluated using 3D PDUS. Nodule volume, vascularization index (VI), flow index (FI), and vascularization flow index (VFI) were calculated using the Virtual Organ Computer-aided Analysis (VOCAL) software, and these indices were then compared with regard to the cytohistopathology-based diagnosis. …
Clinical Significance Of Progastrin-Releasing Peptide, Neuron-Specific Enolase, Chromogranin A, And Squamous Cell Cancer Antigen In Pulmonary Neuroendocrine Tumors, Nuri̇ Tutar, Nur Aleyna Yetki̇n, Cevat Yazici, Ömer Önal, Olgun Kontaş, Fahretti̇n Keleştemur
Clinical Significance Of Progastrin-Releasing Peptide, Neuron-Specific Enolase, Chromogranin A, And Squamous Cell Cancer Antigen In Pulmonary Neuroendocrine Tumors, Nuri̇ Tutar, Nur Aleyna Yetki̇n, Cevat Yazici, Ömer Önal, Olgun Kontaş, Fahretti̇n Keleştemur
Turkish Journal of Medical Sciences
Background/aim: It is not always easy to diagnose pulmonary neuroendocrine tumors (PNETs). The aim of the present study is to make a differential diagnosis by studying the same markers in patients with non-small-cell lung carcinoma (NSCLC), patients with benign lung disease (chronic obstructive pulmonary disease and pneumonia), and healthy volunteers to determine the roles of these markers in pulmonary neuroendocrine tumor diagnosis and to identify their power. Materials and methods: A total of 100 participants including 23 PNET patients and 28 NSCLC patients who were pathologically di-agnosed but not yet treated, 25 participants with benign disease, and 24 healthy volunteers …
Bloodstream Infections In Pediatric Hematology/Oncology Patients: Six Years? Experience Of A Single Center In Turkey, Tuğçe Tural Kara, Tuğba Erat, Aysun Yahşi̇, Hali̇l Özdemi̇r, Di̇lber Tali̇a İleri̇, Eli̇f İnce, Nurdan Taçyildiz, Emel Ünal, Ergi̇n Çi̇ftci̇, Erdal İnce
Bloodstream Infections In Pediatric Hematology/Oncology Patients: Six Years? Experience Of A Single Center In Turkey, Tuğçe Tural Kara, Tuğba Erat, Aysun Yahşi̇, Hali̇l Özdemi̇r, Di̇lber Tali̇a İleri̇, Eli̇f İnce, Nurdan Taçyildiz, Emel Ünal, Ergi̇n Çi̇ftci̇, Erdal İnce
Turkish Journal of Medical Sciences
Background/aim: Bloodstream infections are the major cause of morbidity, increased cost, prolonged hospitalization, and mortality in pediatric patients. Identifying the predominant microorganisms and antimicrobial susceptibilities in centers helps to select effective empirical antimicrobials which leads to positive clinical outcomes. We aimed to identify the causative microorganisms and their antimicrobial susceptibilities in patients with bloodstream infections.Materials and methods: Data belonging to patients with hematological and/or oncological diseases admitted to our hospital with fever between January 2010 and November 2015 were analyzed. Results: In total, 71 patients who had 111 bloodstream infection episodes were included. Responsible pathogens were detected as follows: 35.1% …
Does Smoking Increase The Anesthetic Requirement?, Erdoğan Öztürk, Mustafa Sai̇d Aydoğan, Kazim Karaaslan, Zafer Doğan, Ufuk Topuz
Does Smoking Increase The Anesthetic Requirement?, Erdoğan Öztürk, Mustafa Sai̇d Aydoğan, Kazim Karaaslan, Zafer Doğan, Ufuk Topuz
Turkish Journal of Medical Sciences
Background/aim:To examine the effects of active and passive smoking on perioperative anesthetic and analgesic consumption. Materials and methods: Patients were divided into three groups: group S, smokers; group PS, passive smokers; and group NS, individuals who did not have a history of smoking and were not exposed to smoke. All patients underwent the standard total intravenous anesthesia method. The primary endpoint of this study was determination of the total amount of propofol and remifentanil consumed. Results: The amount of propofol used in induction of anesthesia was significantly higher in group S compared to groups PS and NS. Moreover, the total …
Importance Of 14-3-3eta, Anti-Carp, And Anti-Sa In The Diagnosis Of Seronegative Rheumatoid Arthritis, Emrah Salman, Sali̇h Çeti̇ner, Bariş Boral, Fi̇li̇z Ki̇bar, Eren Erken, Emi̇ne Duygu Ersözlü, Suade Özlem Badak, Reyhan Bi̇li̇ci̇ Salman, Yaşar Sertdemi̇r, Alev Çeti̇n Duran, Akgün Yaman
Importance Of 14-3-3eta, Anti-Carp, And Anti-Sa In The Diagnosis Of Seronegative Rheumatoid Arthritis, Emrah Salman, Sali̇h Çeti̇ner, Bariş Boral, Fi̇li̇z Ki̇bar, Eren Erken, Emi̇ne Duygu Ersözlü, Suade Özlem Badak, Reyhan Bi̇li̇ci̇ Salman, Yaşar Sertdemi̇r, Alev Çeti̇n Duran, Akgün Yaman
Turkish Journal of Medical Sciences
Background/aim: Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial inflammation. The study aimed to assess serum 14-3-3eta, anti-CarP, and anti-Sa in seronegative RA (SNRA) patients who were treatment-naïve as well as in healthy subjects. This is the first study in the literature to examine these autoantibodies together in SNRA patients. Materials and methods: Forty-five treatment-naïve SNRA patients and 45 healthy subjects were recruited. Drugs change the levels of autoantibodies; therefore, patients who took any medication had been excluded from our study. Anti-carbamylated protein, anti-Sa, and 14-3-3eta were measured by using three different ELISA kits.Results: Median serum concentration of …
Nicotinamide N-Methyltransferase Expression And Its Association With Phospho-Akt, P53 Expression, And Survival In High-Grade Endometrial Cancer, Serra Akar, İsmai̇l Harmankaya, Serdar Ugras, Çeti̇n Çeli̇k
Nicotinamide N-Methyltransferase Expression And Its Association With Phospho-Akt, P53 Expression, And Survival In High-Grade Endometrial Cancer, Serra Akar, İsmai̇l Harmankaya, Serdar Ugras, Çeti̇n Çeli̇k
Turkish Journal of Medical Sciences
Background/aim: Nicotinamide N-methyltransferase (NNMT) is an enzyme that is overexpressed in malignancies. NNMT expression has not been previously studied in endometrial cancer (EC). Increased phospho-Akt (pAkt) levels in response to NNMT overexpression have been reported in in vitro studies of different cancer types. We assayed NNMT expression in primary and metastatic high-grade EC and investigated the relationship of NNMT with p53, pAkt, and survival. Materials and methods: NNMT, pAkt, and p53 expressions were assayed in 100 tissue samples of benign endometria, primary EC, and metastatic EC by immunohistochemistry. Results: The NNMT immunoreactivity score was significantly higher in primary high-grade EC …
Comparison Of Bactericidal And Fungicidal Efficacy Of Antiseptic Formulations According To En 13727 And En 13624 Standards, Asli Şahi̇ner, Ece Halat, Evren Alğin Yapar
Comparison Of Bactericidal And Fungicidal Efficacy Of Antiseptic Formulations According To En 13727 And En 13624 Standards, Asli Şahi̇ner, Ece Halat, Evren Alğin Yapar
Turkish Journal of Medical Sciences
Background/aim: In this study, the antibacterial and antifungal properties of the five most commonly used antiseptic formulations were evaluated in terms of different contact times and organic conditions. Materials and methods: Solutions of chlorhexidine digluconate, povidone iodine, isopropyl alcohol, hydrogen peroxide, and tincture of iodine were prepared and tested according to European standards EN 13727 and EN 13624 with different parameters.Results: The results showed that isopropyl alcohol (70% v/v) and tincture of iodine (2%) had greater bactericidal and fungicidal activity against the four tested bacteria and two fungi in all conditions.Conclusion: When the results of the five different active substances …
Does Transrectal Ultrasonography-Guided Biopsy Of The Prostate Lead To Possible Further Metastasis Via Circulating Tumor Cells?, Mustafa Kemal Ati̇lla, Bahatti̇n Avci, Lokman İrkilata, Mustafa Aydin, Alper Bi̇tki̇n, Mevlüt Keleş, İnci̇ Yücel, Mahmut Ulubay
Does Transrectal Ultrasonography-Guided Biopsy Of The Prostate Lead To Possible Further Metastasis Via Circulating Tumor Cells?, Mustafa Kemal Ati̇lla, Bahatti̇n Avci, Lokman İrkilata, Mustafa Aydin, Alper Bi̇tki̇n, Mevlüt Keleş, İnci̇ Yücel, Mahmut Ulubay
Turkish Journal of Medical Sciences
Background/aim: We evaluate whether transrectal ultrasonography (TRUS)-guided prostate biopsy might lead to spillage of tumor cells into peripheral blood as a result of disruption of the epithelial barrier and ultimately result in metastasis. Materials and methods: Eighty-eight patients underwent TRUS-guided prostate needle biopsy due to prostate-specific antigen (PSA) increase or abnormal digital rectal examination at the Samsun Research and Training Hospital (Samsun, Turkey) between April 2016 and September 2018. Approximately 10 mL of whole blood was collected from patients before, 1 week after, and 1 month after biopsy. Samples were analyzed for CD117 positivity and prostate-specific membrane antigen (PSMA) levels …
Cross-Cultural Adaptation, Reliability, And Validity Of The Turkish Version Of The Neck Outcome Score, Şeyda Candeni̇z, Seyi̇t Çitaker, Batuhan Bakirarar
Cross-Cultural Adaptation, Reliability, And Validity Of The Turkish Version Of The Neck Outcome Score, Şeyda Candeni̇z, Seyi̇t Çitaker, Batuhan Bakirarar
Turkish Journal of Medical Sciences
Background/aim: This study aims to determine the validity and reliability of the Turkish version of the Neck OutcOme Score (NOOS).Materials and methods: Two hundred eight patients suffering from nonspecific neck pain participated in the study. Test-retest reliability and internal consistency were assessed using intraclass correlation coefficients (2, 1) and Cronbach's alpha, respectively. The dimensionality was investigated with the factor analysis. The construct validity was determined by testing whether the hypothesis of correlations between NOOS subscales, Short Form-36 subscales, and the Neck Disability Index were met using Spearman's rank correlation coefficient. Ceiling/floor effects and measurement error were tested as well.Results: The …
Mild To Moderate Proteinuria Is A Heralding Sign For Acute Kidney Injury And Mortality For Intensive Care Unit Patients, Haci Hasan Yeter, Tolga Yildirim, Nesri̇n Damla Eyüpoğlu, Tural Pasayev, Abdullah Tarik Aslan, Sila Çeti̇k, Ömer Faruk Akçay, Arzu Topeli̇ İski̇t, Mustafa Arici
Mild To Moderate Proteinuria Is A Heralding Sign For Acute Kidney Injury And Mortality For Intensive Care Unit Patients, Haci Hasan Yeter, Tolga Yildirim, Nesri̇n Damla Eyüpoğlu, Tural Pasayev, Abdullah Tarik Aslan, Sila Çeti̇k, Ömer Faruk Akçay, Arzu Topeli̇ İski̇t, Mustafa Arici
Turkish Journal of Medical Sciences
Background/aim: Lack of early predictors of acute kidney injury is currently delaying timely diagnosis.This study was done to evaluate the relationship between mild to moderate proteinuria and incidence of acute kidney injury (AKI) and 28-day mortality in intensive care unit (ICU) patients. Material and methods: This observational, retrospective study was conducted in the internal medicine ICU. A total of 796 patients were screened and 525 patients were used for this analysis. Proteinuria was measured by urine dipstick test. AKI was defined according to the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines. Results: Patients with dipstick urine protein positivity on admission …
Prevalence Of Atopy And Allergic Rhinitis In Patients With Adult Non-Cystic Fibrosis Bronchiectasis, Eli̇f Yelda Ni̇ksarlioğlu, Saci̇de Rana Işik, Mehmet Ati̇lla Uysal, Derya Ünal, Güngör Çamsari
Prevalence Of Atopy And Allergic Rhinitis In Patients With Adult Non-Cystic Fibrosis Bronchiectasis, Eli̇f Yelda Ni̇ksarlioğlu, Saci̇de Rana Işik, Mehmet Ati̇lla Uysal, Derya Ünal, Güngör Çamsari
Turkish Journal of Medical Sciences
Background/aim: Non-cystic fibrosis bronchiectasis (non-CF BR) is common in developing countries.Limited data are available regarding the impact of atopy, and no data are available regarding allergic rhinitis in patients with adult bronchiectasis.The aim of this study was to evaluate the prevalence of atopy and allergic rhinitis in the clinical conditions of patients with BR.Materials and methods: The study enrolled 101 patients who were diagnosed with non-CF BR using high-resolution computed chest tomography. Allergic rhinitis (AR) was defined by skin prick test (SPT) positivity and the presence of any nasal symptoms (watery runny nose, nasal obstruction, nasal itching, and sneezing). Results: …
Validity And Reliability Study Of The Turkish Version Of The Postoperative Recovery Index Of Patients Undergoing Surgical Intervention, Hande Cengi̇z, Di̇lek Aygi̇n
Validity And Reliability Study Of The Turkish Version Of The Postoperative Recovery Index Of Patients Undergoing Surgical Intervention, Hande Cengi̇z, Di̇lek Aygi̇n
Turkish Journal of Medical Sciences
Background/aim: For the purpose of providing the optimal postoperative care for patients and assisting them in terms of recovery, their health conditions and particular symptoms should be evaluated systematically with an appropriate measurement tool. This research was designed with the purpose of conducting the validity and reliability study of the Postoperative Recovery Index-Turkish Version (PoRI-TR) and determining the postoperative recovery conditions.Materials and methods: The sample of this study, which was planned methodologically and analytically, consisted of 382 patients who had a surgical intervention in a university hospital between September 2016 and June 2017. Analyses concerning the Turkish validity and reliability …
Investigation Of The Relationship Between Ischemic Stroke And Endothelial Nitric Oxide Synthase Gene Polymorphisms [G894t, Intron 4 Vntr And T786c], Süleyman Ömer Anliaçik, Osman Serhat Tokgöz, Ayşegül Zamani̇, Mahmut Selman Yildirim, Mehmet Si̇nan İyi̇soy
Investigation Of The Relationship Between Ischemic Stroke And Endothelial Nitric Oxide Synthase Gene Polymorphisms [G894t, Intron 4 Vntr And T786c], Süleyman Ömer Anliaçik, Osman Serhat Tokgöz, Ayşegül Zamani̇, Mahmut Selman Yildirim, Mehmet Si̇nan İyi̇soy
Turkish Journal of Medical Sciences
Background/aim: We aimed to investigate the associations between endothelial nitric oxide synthase(eNOS) gene polymorphisms [G894T (rs1799983)], intron 4 (27-bpTR) variable number tandem repeat (VNTR) and T786C (rs2070744), and ischemic stroke in the Anatolian population.Materials and methods: This case-control study included 112 patients with "stroke of undetermined etiology" and 160 controls. Real-time polymerase chain reaction (RT-PCR) analysis was used to analyze these polymorphisms. Between-group frequencies of alleles and genotypes were compared using binary logistic regression analysis.Results: No significant difference was observed between the two groups in terms of the genotype and allele distributions of the eNOS G894T (rs1799983) polymorphism (P > 0.05). …
The Efficacy And Safety Of Targeted Narrowband Uvb Therapy: A Retrospective Cohort Study, Kübra Esen Salman, İlknur Altunay, Andaç Salman
The Efficacy And Safety Of Targeted Narrowband Uvb Therapy: A Retrospective Cohort Study, Kübra Esen Salman, İlknur Altunay, Andaç Salman
Turkish Journal of Medical Sciences
Background/aim: Phototherapy is a safe and effective treatment modality for numerous dermatological conditions. Recently, targeted phototherapy modalities have gained importance due to their advantages over conventional phototherapy.This retrospective study aimed to evaluate the safety and efficacy of targeted narrowband UVB phototherapy in patients with dermatological disorders.Materials and methods: This single-center study included 173 patients who were treated with targeted narrowband UVB phototherapy. Demographic features, phototherapy parameters, and adverse effects were evaluated in all patients, and the treatment response was assessed in patients who attended at least one follow-up visit. Results: A total of 173 patients (102 females; 71 males) with …
Relationship Between The Earlobe Crease And Brain White Matter Abnormalities In Apparently Healthy Subjects*, Hati̇ce Ayça Ata Korkmaz
Relationship Between The Earlobe Crease And Brain White Matter Abnormalities In Apparently Healthy Subjects*, Hati̇ce Ayça Ata Korkmaz
Turkish Journal of Medical Sciences
Background/aim: In the present study we aimed to investigate whether the earlobe crease (ELC) might provide predictive information about white matter intensities (WMIs) in the brain that reflect brain aging.Materials and methods: A total of 350 individuals examined from January 2016 to July 2016 were screened. Patients with known demyelinating white matter disease, neurodegenerative disorders, cerebrovascular event history, or brain tumors were excluded from the study. Finally, 285 cases were included in the study. The four-point cerebral intensity classification system of Fazekas was used in the evaluation of the brain. The ELC was evaluated by inspection.Results: A total of 285 …
Assessment Of Cardiac And Vessel Functions In Childhood Psoriasis, Berna Şaylan Çevi̇k, Fi̇gen Akalin, Eli̇f Erolu, Di̇lek Seçki̇n Gençosmanoğlu, Safi̇ye Atlas Tüli̇n Ergun
Assessment Of Cardiac And Vessel Functions In Childhood Psoriasis, Berna Şaylan Çevi̇k, Fi̇gen Akalin, Eli̇f Erolu, Di̇lek Seçki̇n Gençosmanoğlu, Safi̇ye Atlas Tüli̇n Ergun
Turkish Journal of Medical Sciences
Background/aim: Psoriasis is a chronic inflammatory disease. The effect of psoriasis on the cardiovascular system has not been studied in children before. We studied ventricular strain and vascular functions to assess early cardiovascular effects of psoriasis during childhood. Materials and methods: The study population consisted of 20 psoriatic and 20 age- and sex-matched control subjects. Two-dimensional echocardiography images, longitudinal and global strain, and carotid and brachial ultrasound studies were performed. Results: The mean age of psoriatic children was 14 ± 0.89 years and that of the controls was 14.05 ± 0.88. There were significant increases in terms of interventricular septum …
Elevated Neutrophil To Lymphocyte Ratio As An Indicator Of Secondary Erythema Nodosum, A Retrospective Observational Study, Yildiz Hayran, Ayşe Öktem, Emi̇ne Buket Şahi̇n, Pinar İncel Uysal, Nuran Alli, Başak Yalçin
Elevated Neutrophil To Lymphocyte Ratio As An Indicator Of Secondary Erythema Nodosum, A Retrospective Observational Study, Yildiz Hayran, Ayşe Öktem, Emi̇ne Buket Şahi̇n, Pinar İncel Uysal, Nuran Alli, Başak Yalçin
Turkish Journal of Medical Sciences
Background/aim: Erythema nodosum (EN) is an inflammatory disorder of subcutaneous tissue. Although etiopathogenesis of the disease is unknown, many predisposing factors such as infections, systemic disease, and drugs have been identified. Neutrophil to lymphocyte ratio (NLR) has been shown to be a novel inflammatory marker in many dermatological diseases. The aim of our study is to investigate NLR in EN patients and evaluate its relation to the underlying cause of the disease.Materials and methods: Between 2014 and 2018, clinical and laboratory data of 395 patients diagnosed with EN and 395 controls were extracted from patient files. EN patients were grouped …
Optimum Recording Time Of Routine Electroencephalogram For Adults With Epilepsy*, Kemal Tutkavul, Yilmaz Çeti̇nkaya
Optimum Recording Time Of Routine Electroencephalogram For Adults With Epilepsy*, Kemal Tutkavul, Yilmaz Çeti̇nkaya
Turkish Journal of Medical Sciences
Background/aim: This study aimed to reveal the optimum recording time of routine electroencephalogram (EEG) for adults with epilepsy.Materials and methods: In this clinical observational study we investigated features of paroxysms that emerged in EEGs recorded for 45 min in adults with epilepsy.Results: Paroxysms were detected in 38.14% of 97 patients. The probability of occurrence of paroxysm during the first 10 min was found to be statistically significantly low in comparison to the first 30 and 45 min (respectively P = 0.004, P = 0.0001). This probability was found to increase insignificantly when comparing the first 20 min with the first …
Analyzing The Effect Of Laparoscopy Duration Time On Peroperative Gastroesophageal Reflux, Gökhan Berktuğ Bahadir, Hakan Taşkinlar, Caner İsbi̇r, İsa Killi, Di̇lek Yünlüel, Ülkü Çömelekoğlu, Ali̇ Nayci
Analyzing The Effect Of Laparoscopy Duration Time On Peroperative Gastroesophageal Reflux, Gökhan Berktuğ Bahadir, Hakan Taşkinlar, Caner İsbi̇r, İsa Killi, Di̇lek Yünlüel, Ülkü Çömelekoğlu, Ali̇ Nayci
Turkish Journal of Medical Sciences
Background/aim: Intraabdominal pressure (IAP) is one of the main reasons for gastroesophageal reflux (GER). This study investigates whether IAP during laparoscopic surgery leads to GER in a time-dependent manner.Materials and methods: In a laparoscopy model, 15 mmHg IAP was created in 8 Wistar albino rats in the Trendelenburg position (TP). A 5 mm laparotomy was performed in the left lower abdominal region, and a 6 Fr catheter was placed intraabdominally. Air was insufflated into the abdominal cavity, and the pressure was kept constant at 15 mmHg. Esophageal pH alterations were measured by pH sticks for 4 h every 30 min.Results: …
Is There Any Difference Between Endometrial Hyperplasia And Endometrial Carcinoma In Terms Of Expression Of Trpm2 And Trpm7 Ion Channels?, Emre Yalçin, Şehmus Pala, Remzi̇ Atilgan, Tuncay Kuloğlu, Ebru Önalan, Gökhan Artaş, İlay Buran
Is There Any Difference Between Endometrial Hyperplasia And Endometrial Carcinoma In Terms Of Expression Of Trpm2 And Trpm7 Ion Channels?, Emre Yalçin, Şehmus Pala, Remzi̇ Atilgan, Tuncay Kuloğlu, Ebru Önalan, Gökhan Artaş, İlay Buran
Turkish Journal of Medical Sciences
Background/aim: This study compared TRPM2 and TRPM7 ion channel gene expression and immunohistochemical staining in endometrial hyperplasia and endometrium adenocarcinoma. Materials and methods: Sections were taken from paraffin blocks of 120 patients who were divided into 6 groups as follows: G1 (n = 20), proliferative endometrium (PE); G2 (n = 20), EH without atypia; G3 (n = 20), EH with atypia; G4 (n = 20), stage 1A, grade 1 EC; G5 (n = 20), stage 1A, grade 2 EC; and G6 (n = 20), stage 1A, grade 3 EC. TRPM2 and TRPM7 genes were analyzed with qRT-PCR in paraffin-embedded tissue …
Antibiotic Resistance Pattern And Spa Types Of Staphylococcus Aureus Strains Isolated From Food Business And Hospital Kitchen Employees In Çanakkale, Turkey, Nesri̇n Çakici, Alper Akçali, Nükhet Ni̇lüfer Zorba
Antibiotic Resistance Pattern And Spa Types Of Staphylococcus Aureus Strains Isolated From Food Business And Hospital Kitchen Employees In Çanakkale, Turkey, Nesri̇n Çakici, Alper Akçali, Nükhet Ni̇lüfer Zorba
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine antibiotic resistance profiles and spa types of Staphylococcus aureus strains isolated from food business employees in Çanakkale, Turkey.Materials and methods:S.aureus isolates were collected from hand and nasal swabs of 300 individuals working in 17 food businesses and 9 hospital kitchens. All S. aureus isolates obtained from each carrier were typed by staphylococcal protein A (spa) typing method.Staphylococcal cassette chromosome mec (SCCmec) and multilocus sequence typing (MLST) of MRSA were performed by sequencing method.Results: Of the 300 individuals, 125 (41.6%) were found to be carriers of S. aureus, 215 isolates of which …
In Vitro Combination Of Tigecycline With Other Antibiotics In Stenotrophomonas Maltophilia Isolates, Di̇lek Karamanlioğlu, Murat Di̇zbay
In Vitro Combination Of Tigecycline With Other Antibiotics In Stenotrophomonas Maltophilia Isolates, Di̇lek Karamanlioğlu, Murat Di̇zbay
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine the usefulness of tigecycline in combination treatment of Stenotrophomonas maltophilia infections by evaluating the in vitro synergistic effects of tigecycline with various antibiotics using the E-test method.Materials and methods: Synergy testing by E-test was performed with various antibiotic combinations in 10 S. maltophilia isolates identified as a cause of infection. The antibiotics used in the study included tigecycline (TGC), cefoperazone-sulbactam (CPS), ceftazidime (TZ), levofloxacin (LEV), and trimethoprim-sulfamethoxazole (cotrimoxazole)(TS). Four different combinations (TGC-CPS, TGC-TZ, TGC-LEV, TGC-TS) were studied with the E-test synergy method. Results: S. maltophilia isolates were found to have the …