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Experimental Investigation Of Mixing Time In A Stirred, Torispherical-Bottomed Tank Equipped With A Retreat-Blade Impeller, Nonjaros Chomcharn May 2009

Experimental Investigation Of Mixing Time In A Stirred, Torispherical-Bottomed Tank Equipped With A Retreat-Blade Impeller, Nonjaros Chomcharn

Theses

Glass-lined reactors are typically used in the pharmaceutical and specialty chemicals industries because of their material compatibility with most reactants and their cleanability. These reactors are typically equipped with a retreat-blade impeller placed close to the bottom of the tank a single baffle mounted from the top. The mixing performance of such reactors has not received significant attention in the literature, despite their ubiquitous presence in the pharmaceutical industry. In particular, mixing time, i.e., the time required by the system to achieve a predefined level of homogeneity, has not been studied to any significant degree.

In this work, the mixing …


Mixing Performance Of A Novel, Continuous Confined Impinging Jets Mixer Using Competitive Reactions, Han Zheng May 2009

Mixing Performance Of A Novel, Continuous Confined Impinging Jets Mixer Using Competitive Reactions, Han Zheng

Theses

In this work, a novel continuous flow apparatus featuring the impingement of fluid jet streams in the presence of ultrasonic energy provided by an ultrasonic probe was tested using competitive reactions in order to determine its mixing effectiveness. The ultrasonic energy enhances micromixing of the fluid jet streams, which results in an overall mixing effectiveness improvements in different physical and chemical processes.

In the competitive reactions system used here (third Bourne reaction), one stream containing sodium hydroxide was continuously fed to the first impinging jet, while an aqueous solution of hydrochloric acid and ethyl chloroacetate was fed to the second …


Preparation Of Nanovehicles For Targeted Drug Delivery, Anagha Avinash Bhakay Jan 2009

Preparation Of Nanovehicles For Targeted Drug Delivery, Anagha Avinash Bhakay

Theses

Application of nanotechnology in pharmaceutical research has opened new frontiers for drug development and its efficient delivery. In recent years, the focus of the research has been on the engineering of nano/micro-particulate structures for efficient and targeted delivery of drugs for selective and enhanced absorption. This work throws light on the preparation of biodegradable and non-toxic nanoparticulate systems for targeted drug delivery. The drug vehicles were made by two different processes namely electrostatic interactions and desolvation process. The drug carriers made by these processes were found to be in the size range of 150-200nm which is necessary for cellular uptake …


Participation And Determinants Of Physical Activity Amongst Irish 3rd Level Students., Jonathan Lerner Jan 2009

Participation And Determinants Of Physical Activity Amongst Irish 3rd Level Students., Jonathan Lerner

Theses

Currently, there is a dearth of research investigating physical activity patterns among Irish third level young adults (17-22 year olds). Both national and international research report that levels of physical activity decline in adolescence, this trend being most pronounced among females. Various biological, psychological, social, and environmental determinants have been found to influence physical activity; however, specific factors associated with the decline in activity during adolescence remain largely unknown. This research study examines participation and determinants of physical activity among Irish third level students.

A “National questionnaire” was administered to a sample of 532 students from Health Education Authority (HEA) …


The Detection And Analysis Of Selected Pathogens In The Water Supply Of Dairy Cohort Herds., Niall Drummond Jan 2009

The Detection And Analysis Of Selected Pathogens In The Water Supply Of Dairy Cohort Herds., Niall Drummond

Theses

The issue of food safety is a growing concern to Irish agriculture and to the food industry. In the last twenty years, many novel pathogens, which can cause concern to the food industry, have been identified. Organisms such as Verocytotoxigenic Escherichia coli (VTEC) cause hemorrhagic colitis and Haemolytic Uremic Syndrome (HUS), which is the major cause of acute renal failure in children in many countries, and it’s presence in food is a cause of growing concern. Other pathogens causing concern are those implicated as causative agents of Acute Gastroenteritis (AGE) and these can be bacterial, viral and parasitic organisms.

Consumption …


A Longitudinal Examination Of The Contribution Of Perceived Motor Competence And Actual Motor Competence To Physical Activity In 6 To 9 Year Old Children, Fleur Mcintyre Jan 2009

A Longitudinal Examination Of The Contribution Of Perceived Motor Competence And Actual Motor Competence To Physical Activity In 6 To 9 Year Old Children, Fleur Mcintyre

Theses

This study examined the relationship between perceived motor competence, actual motor competence and physical activity. In particular, it aimed to identify the impact of perceived motor competence (PMC), actual motor competence (AMC), and age and gender on the physical activity levels of young children. A number of factors have been identified as key contributors to children’s physical activity levels. However, there had been little investigation into their developing impact and subsequent relationship with emergent physical activity levels, particularly in the younger primary age groups.

Physical activity, AMC and PMC measures were collected from 6-, 7-, 8-, and 9-year-old boys and …