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Expression Profile Analysis Of Micrornas During The Oestrous Cycle Of Qira Black Sheep, Xi Chen, Hanying Chen, Song Jiang, Chaocheng Li, Xiancun Zeng
Expression Profile Analysis Of Micrornas During The Oestrous Cycle Of Qira Black Sheep, Xi Chen, Hanying Chen, Song Jiang, Chaocheng Li, Xiancun Zeng
The Thai Journal of Veterinary Medicine
Ovarian follicular development is closely regulated by a multitude of genes and specific non-coding RNAs (ncRNAs), which are typically altered during the oestrous cycle. Identification of the microRNAs (miRNA) expression profiles in sheep ovaries during the oestrous cycle is a prerequisite to further understanding their functional status. This study presents a genome-wide analysis of miRNAs from three groups of Qira black sheep: oestrus (day 0), dioestrus (day 10) and pro-oestrus (day 14). A total of 545 conserved miRNAs and 206 novel miRNAs were identified. Furthermore, 229 differentially expressed miRNAs were screened in three comparisons and 16 miRNAs were found to …