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Investigation Of Antidiabetic Of Antidiabetic Activity And Pharmacokinetics In Herbo-Mineral Ayurvedic Formulation ‘Arogyavardhini Gutika In Streptozotocin Induced Wistar Rat, Ruchi Bhattacharya, Bina Gidwani Prof., Shiv Shankar Shukla Prof., Ravindra Kumar Pandey Prof.
Investigation Of Antidiabetic Of Antidiabetic Activity And Pharmacokinetics In Herbo-Mineral Ayurvedic Formulation ‘Arogyavardhini Gutika In Streptozotocin Induced Wistar Rat, Ruchi Bhattacharya, Bina Gidwani Prof., Shiv Shankar Shukla Prof., Ravindra Kumar Pandey Prof.
Palestinian Medical and Pharmaceutical Journal
Aim: Herbs, spices, and minerals are important therapeutic attributes of ayurvedic formulations. The formulation Arogyavardhini Gutika is mentioned in the essential drug list of the Ayurvedic Formulary of India. It has a claimed safety profile and is used for the treatment of jaundice, leprosy, fever, oedema, obesity, skin disorders, and other hepatic issues. Methods: An in- vitro study was performed by alpha-amylase inhibition using starch, iodine, and dinitrosalicyclic acid. An in-vivo study was performed using a streptozotocin-induced diabetic rat model. Graded doses of Arogyavardhini gutika (200 and 500 mg/kg) were administered orally for 14 days to normal and streptozotocin-induced …