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Programmatic Desensitization Of The Cough Reflex In Patients With Refractory Chronic Cough, Emma Bozarth Dailey
Programmatic Desensitization Of The Cough Reflex In Patients With Refractory Chronic Cough, Emma Bozarth Dailey
Graduate Student Theses, Dissertations, & Professional Papers
Aim: The purpose of this blinded, randomized, placebo-controlled pilot clinical trial was to determine the potential of treating refractory chronic cough (RCC) using a progressive desensitization model paired with behavioral cough suppression.
Methods: Twelve adults with chronic cough who had failed behavioral cough treatment enrolled in and completed the study. Participants were randomly assigned to a treatment (n=8) or placebo group (n=4). The study consisted of three phases. During Phase I, participants completed baseline testing, including cough sensitivity testing with capsaicin, the Leicester Cough Questionnaire (LCQ), urge-to-cough-testing, and 24-hour cough frequency testing. During Phase II, participants practiced behavioral cough suppression …