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Medicine and Health Sciences

Electronic Theses and Dissertations, 2020-

Theses/Dissertations

2023

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Utilization And Costs Of Home Hemodialysis, In-Center Hemodialysis, And Peritoneal Dialysis Among Patients With End-Stage Renal Disease (Esrd) In The United States, Andres Mauricio Garcia Sierra Aug 2023

Utilization And Costs Of Home Hemodialysis, In-Center Hemodialysis, And Peritoneal Dialysis Among Patients With End-Stage Renal Disease (Esrd) In The United States, Andres Mauricio Garcia Sierra

Electronic Theses and Dissertations, 2020-

Chronic kidney disease (CKD) is a condition that requires access to renal replacement therapies (RRTs) to enable patients to live. The use of such therapies has been continuously researched due to the high cost to payers and their patients. This dissertation aimed to analyze the incidence, prevalence, and mortality of renal replacement therapies in patients with end-stage renal disease (ESRD), and document cost trends and analyze possible inequalities in access to these therapies. Based on an integrated health risk management (IHRM) model, this study examined patient characteristics associated with renal replacement therapies in ESRD patients through a pooled cross-sectional study …


Exploring Risk Factors Associated With Post-Traumatic Stress Disorder Symptomatology In Police, Lori Camacho Jan 2023

Exploring Risk Factors Associated With Post-Traumatic Stress Disorder Symptomatology In Police, Lori Camacho

Electronic Theses and Dissertations, 2020-

Mental health outcomes, especially post-traumatic stress disorder (PTSD), in police have become more of a concern for law enforcement administrators, peers, family and friends. Using culture as a theoretical framework, the current cross-sectional, convergent mixed methods study explored the relationship between personal cumulative exposure to different types of critical incidents and likelihood of reporting PTSD symptoms in a sample of officers (n=71) from one municipal police department. This study also examined how personal cumulative exposure to different types of critical incidents and likelihood of reporting symptoms of PTSD may be moderated by the degree of perception of social support from …


A Digitally Enhanced Virtual Cognitive Behavior Skill Building Intervention To Reduce Parent Stress And Family Obesogenic Behaviors, Sharlene Smith Jan 2023

A Digitally Enhanced Virtual Cognitive Behavior Skill Building Intervention To Reduce Parent Stress And Family Obesogenic Behaviors, Sharlene Smith

Electronic Theses and Dissertations, 2020-

Parental stress is associated with increased obesogenic family lifestyle behaviors contributing to childhood obesity. Novel interventions are needed to reduce parental stress and improve healthy lifestyle behaviors for preschool-age children and families. The primary study aim was to analyze preliminary effects of a digitally enhanced evidence-based cognitive- behavior skill-building (CBSB) intervention on parental stress and healthy lifestyle behaviors (diet and physical activity) among parents of preschool-age children. A secondary aim was to evaluate feasibility/acceptability of this school-based virtual intervention during the COVID-19 pandemic. The 12-week intervention involved text messaging and three pre-recorded CBSB educational video presentations accessed by parents of …


Role Of Vitamin D, Folate, And Cobalamin Deficiency In Mycobacterium Avium Paratuberculosis Infection And Inflammation, Joseph Vaccaro Jan 2023

Role Of Vitamin D, Folate, And Cobalamin Deficiency In Mycobacterium Avium Paratuberculosis Infection And Inflammation, Joseph Vaccaro

Electronic Theses and Dissertations, 2020-

Vitamin D, folate, and cobalamin (vitamin B12) are crucial micronutrients in human physiology that are necessary for healthy calcium, phosphorus, and single-carbon metabolism. Recent studies have indicated that these vitamins also affect the inflammatory response in ways unrelated to their well-characterized deficiencies. Accordingly, analysis of their effect on chronic inflammatory diseases like Crohn's disease (CD) is warranted. This investigation examines the effects of vitamin deficiency on macrophages and intestinal epithelial cells upon exposure to Mycobacterium avium paratuberculosis (MAP,) a pathogen capable of triggering CD, to model the inflammatory response in clinical CD patients. ELISA analysis of CD patient plasma established …


Topographical Distribution And Morphology Of Sympathetic Postganglionic Innervation And Chronic Intermittent Hypoxia (Cih) Induced Remodeling Of The Whole Heart At Single Cell/Axon/Varicosity Scale, Ariege Bizanti Jan 2023

Topographical Distribution And Morphology Of Sympathetic Postganglionic Innervation And Chronic Intermittent Hypoxia (Cih) Induced Remodeling Of The Whole Heart At Single Cell/Axon/Varicosity Scale, Ariege Bizanti

Electronic Theses and Dissertations, 2020-

The sympathetic nervous system is crucial for controlling multiple cardiac functions and its overactivity is associated with many cardiovascular diseases (CVD). Chronic intermittent hypoxia (CIH) is a current model for sleep apnea, which constitutes a major risk factor for CVD through sympathetic overactivity. However, a comprehensive neuroanatomical map of the sympathetic innervation of the heart is unavailable which impedes our understanding of the remodeling of this map in pathological conditions. First, we used a combination of state-of-the-art techniques, including flat-mount tissue processing, immunohistochemistry for tyrosine hydroxylase (TH, a sympathetic marker), confocal microscopy and Neurolucida 360 software to trace, digitize, and …


The Successful Characteristics That Contribute To Black Male Students Matriculating Into Medical School, Cedric Brown Jan 2023

The Successful Characteristics That Contribute To Black Male Students Matriculating Into Medical School, Cedric Brown

Electronic Theses and Dissertations, 2020-

In 2019, individuals that identified as Black represented 13.4% of the U.S. population, 12.5% of the undergraduate student enrollment population and 7.1% of the medical school population. Subsequently, this has yielded a 5% Black physician population and workforce consisting of just 2.3% Black male physicians (AAMC, 2018). The disproportionately low Black physician representation contributes to greater healthcare disparity outcomes within the U.S. Black population. This study is centered on the post-positive characteristics of Black male medical students that have successfully overcome barriers to entry and matriculated into medical school. The phenomenological post-positive study was conducted through the lens of Self-Efficacy …


The Role Of Savoring In The Relationship Between Concussion History And Consummatory Reward, John O'Donnell Jan 2023

The Role Of Savoring In The Relationship Between Concussion History And Consummatory Reward, John O'Donnell

Electronic Theses and Dissertations, 2020-

Concussions are a relatively common neurological injury and are associated with several adverse outcomes including depression. Anhedonia is a core feature of depression, with multiple subtypes, including consummatory anhedonia (i.e., diminished reward liking). Reward liking is related conceptually to the practice of savoring pleasurable stimuli. Savoring has been a component of mindfulness-based interventions that have efficacy in treating depressive symptoms. The purpose of this study was to examine the relationships between lifetime concussion history, reward liking, savoring, and depression severity. 293 participants (56% women; mean age: 19.31) completed an online questionnaire and computer-based image savoring task. Contrary to expectations, no …


Optimizing Biomechanical Models: Estimation Of Muscle Tendon Parameters And Ankle Foot Orthosis Stiffness, Sepehr Ramezani Jan 2023

Optimizing Biomechanical Models: Estimation Of Muscle Tendon Parameters And Ankle Foot Orthosis Stiffness, Sepehr Ramezani

Electronic Theses and Dissertations, 2020-

The complexity of the human musculoskeletal system presents challenges in accurately identifying its characteristics, particularly due to the presence of redundant actuators on a single joint. Non-invasive measures are necessary to overcome these challenges. Optimization algorithms have emerged as a crucial tool to advance subject-specific musculoskeletal modeling allows a more realistic representation of biomechanical behaviors, enhancing our understanding of human movement and enabling better clinical decision-making. Furthermore, optimization algorithms play a vital role in customizing rehabilitation and assistive devices, such as orthoses and prostheses. The current ankle-foot orthosis (AFO) stiffness measurement methods require bulky, complex designs, and often permanent modification …