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Returning Home And Leaving Again: A Phenomenological Investigation Of A Sojourner’S Experience, Victoria Christofi

Doctoral Dissertations

Two studies were conducted for this project. The goal of the first study was to describe the structure of the experience of individuals who have returned home after their stay abroad. The goal of the second study was to describe the structure of the experience of individuals who have returned to the country in which they studied, after having returned home. To accomplish these goals, phenomenological interviews were conducted with seventeen participants. In the first study, nine participants were interviewed in their own country after they had been abroad for their studies. In the second study, eight participants were interviewed; …

“Effects Of N-3 And N-6 Polyunsaturated Fatty Acids On Human Promyelocytic Hl- 60 Cells, Robert Clements Gillis

Doctoral Dissertations

Enteral nutrition with eicosapentaenoic acid (EPA; 20:5 n-3) and γ-linolenic acid (GLA; 18:3 n-6) decreased pulmonary inflammation by reducing neutrophil counts and chemotactic factors in bronchoalveolar lavage fluid during acute respiratory distress syndrome (ARDS). We hypothesize that the antiinflammatory effects of EPA and GLA may be due, in part, to induction of neutrophil apoptosis. Neutrophil apoptosis is an important physiological process in the resolution of pulmonary inflammation. Furthermore, pro-inflammatory eicosanoids formed from arachidonic acid (AA) by lipoxygenase (LO) and cyclooxygenase (COX) pathways have been shown to inhibit apoptosis in certain cell types. The purpose of this dissertation is to determine …

The Role Of Polyglutamine Aggregate Cytotoxicity In Huntington’S Disease, Wen Yang

Doctoral Dissertations

Polyglutamine diseases refer to a group of neuro-degenerative diseases including Huntington's disease , that share the same mutational basis: expansion of a CAG repeat coding sequence that encodes for a polyglutamine repeat in the respective proteins. Neuronal intranuclear inclusions (NII) formed by the aggregation of the expanded polyglutamine proteins is a hallmark of polyglutamine diseases. However, it is still under debate whether the polyglutamine aggregates are toxic to the cells, and if so, which aggregated forms are the toxic species. While important data has been provided by the existing transfected cell and transgenic animal models, technical aspects have limited our …

Psychological Reactance As A Personality Characteristic: Relationships To Attachment And Autonomy, Maurine Traville Hargrove Ladner

Doctoral Dissertations

Psychological reactance is a construct that motivates people to restore lost or threatened freedoms (Brehm, 1966). Research is beginning to show that psychological reactance may be related to family of origin dynamics. Autonomy is developed through a secure attachment. Dowd (1993) stated that autonomy is fostered by an optimal level of reactance, and one's personal identity is dependent on the development of a flexible autonomy. This study explored the relationship between psychological reactance and attachment. Additionally, research has suggested that level of reactance may be related to level of autonomy. This relationship was empirically explored. Participants were assessed using the …

An Investigation Of The Relationship Among Life-Skills, Self-Esteem, And Well-Being In Adults, Scott David Meche

Doctoral Dissertations

This study examined the relationship among life-skills, self-esteem, and well-being in 278 adults. Adults were classified into three age groups. Of the 278 participants, 96 were young adults, 92 were middle-aged, and 90 were older adults. Life-skills, global organizations of general coping skills that are learned behaviors which enable effective functioning, were assessed with the Life-Skills Inventory - Adult Form (Gazda, Illovsky, & Taylor, 1991). Analyses were performed to understand the influence of four generic life-skills areas, interpersonal communication/human relations, problem-solving/decision making, identity development/purpose in life, and physical fitness/health maintenance, on self-esteem. Self-esteem was measured with the Self-Esteem Inventory-Adult Form …

Effects Of Diabetes And Aging On Posture And Acceleration Thresholds During Lateral Translations, Samantha Jean Richerson

Doctoral Dissertations

Research objectives. One source of falls in the elderly may be an inability to sufficiently adjust to transient postural perturbations or slips. Identifying useful predictors of fall potential, as well as factors that affect the ability of an individual to detect a movement of the standing support surface may provide insight into postural stability and methods to increase stability in elders. To do this, acceleration thresholds to short, precise, lateral platform translations and the resultant psychophysical responses of adults with early Type 2 diabetes to age-matched controls and young adults were measured.

Methods. Using an innovative SLIP-FALLS platform, …