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Articles 1 - 8 of 8
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Novel Application Of Graphene Oxide Based-Biosensor Utilizing Crispr/Dcas9 For Rapid Detection Of Antibiotic Resistance Genes, Joel Omage
Masters Theses & Specialist Projects
Antibiotic resistance is one of the biggest public health challenges globally. To combat this threat, we have designed a method for the facile and rapid detection of antibiotic resistance gene (ARG) in bacteria. We utilized an emerging tool termed the clusters of regularly interspaced short palindromic repeats (CRISPR) in complex with deactivated CRISPR associated proteins (dCas9) on conjugated 2-dimensional graphene oxide (GO) sheets. Nuclease-deactivated Cas9 in complex with customized single guided RNA (sgRNA) was used for the target DNA recognition. The sgRNA was easy to design and we demonstrated that it is complementary to its target sequence by performing a …
Validation Of A Novel Vo2max Protocol, Griffin Green
Validation Of A Novel Vo2max Protocol, Griffin Green
Masters Theses & Specialist Projects
Though there are several to choose from, the Bruce protocol is the most commonly utilized treadmill protocol when assessing maximal oxygen consumption (VO2max). Originally developed for cardiac patients, the Bruce protocol may not be an appropriate treadmill protocol for young or trained individuals with higher levels of cardiorespiratory fitness. The steep grade used often leads localized muscular fatigue, which may cause participants to end the test prior to reaching their true VO2max. Another popular protocol, the Astrand, also utilizes a steep grade, but the speed remains constant. Similar to the Bruce, the Astrand protocol may not prompt a maximal cardiovascular …
An Application Of The Interpersonal Psychological Theory Of Suicide In College-Age Survivors Of Sexual Assault, Ava Katherine Fergerson
An Application Of The Interpersonal Psychological Theory Of Suicide In College-Age Survivors Of Sexual Assault, Ava Katherine Fergerson
Masters Theses & Specialist Projects
Sexual victimization is a pervasive public health concern that disproportionately affects college students and results in severe mental and physical health risks for survivors. Despite low prevalence rates in the general population, a national study found that 33% of survivors of rape reported suicidal ideation, and 13% actually made a suicide attempt (Kilpatrick et al., 1992). Although it is clear that survivors of sexual violence are at increased risk for suicide, knowledge is largely limited to epidemiological studies. Few studies have integrated theories of suicide to understand how and why this population is at such elevated risk for suicidal thoughts …
Factors Influencing Both Maternal And Infant Body Composition At Two Years Postpartum, Samantha Henry
Factors Influencing Both Maternal And Infant Body Composition At Two Years Postpartum, Samantha Henry
Masters Theses & Specialist Projects
Maternal body composition (BC) and physical activity (PA) level during pregnancy both contribute to infant body composition; however, few studies follow children beyond the early weeks to determine the longer-term implications of maternal lifestyle on offspring health. The purpose of this study was threefold: 1) Determine the role of maternal obesity on offspring BC at 2 years of age; 2) Determine the role of PA during pregnancy on maternal and infant BC at two years postpartum; and 3) Determine whether BC at birth (assessed via air displacement plethysmography [PEA POD]) is related to BC at two years of age (assessed …
Effects Of Bingocize® On Overall Physical Activity, Functional Performance, Blood Glucose Level, Sleep Quantity, And Quality Among Older Adults In Assisted-Living Facilities, Sepehr Rassi
Masters Theses & Specialist Projects
Bingocize® has been established as an effective falls prevention exercise program for older adults, but its effects on older adults residing in assisted-living facilities have not been examined. The purpose of this investigation was to assess the effects of Bingocize® on overall physical activity level, functional performance, blood glucose level, sleep quantity and quality in older adults who live in assisted-living facilities. Participants (N = 13; mean age 86.23 ± 3.90) were asked to participate in Bingocize® while wearing activity trackers (Fitbit Charge 3 HR) for 10 weeks. The activity trackers were used to assess the average number of steps …
Reliability And Validity Of An Assessment Of Engagement In Nursing Home Residents During Bingocize®, Elizabeth Batson Apelt
Reliability And Validity Of An Assessment Of Engagement In Nursing Home Residents During Bingocize®, Elizabeth Batson Apelt
Masters Theses & Specialist Projects
Research suggests nursing home residents are often socially isolated and physically inactive despite overwhelming evidence that both social engagement and physical activity are crucial for healthy aging (Jones, Sung, & Moyle, 2018; Yen & Lin, 2018; Ice, 2002; Jansson et al., 2017). Bingocize® is a program that combines exercise and the game of Bingo to improve the quality of life, physical health, and social engagement of certified nursing facility (CNF) residents. The purpose of this study is to determine the level of social engagement displayed by CNF residents during Bingocize® using the Fun and Social Engagement Evaluation (FUSE). Reliability and …
Is Physical Activity During Late Pregnancy Related To Infant Body Composition At Birth?, Brenna Menke
Is Physical Activity During Late Pregnancy Related To Infant Body Composition At Birth?, Brenna Menke
Masters Theses & Specialist Projects
Exercise is typically regarded as having a positive impact on maternal and infant health. However, the relationship between maternal physical activity and infant body composition is unclear. The aim of this project was to determine how a physically active lifestyle during late pregnancy influences infant anthropometrics at birth. Pregnant women (34-39 weeks gestation) with low-risk pregnancies were given the Pregnancy Physical Activity Questionnaire (PPAQ) and an accelerometer to wear on their non-dominant wrist for seven consecutive days. Approximately 24-48 hours after delivery, infant body composition was assessed utilizing air displacement plethysmography at the patients’ bedside. Fifty-five pregnant women participated (age: …
H-Discrete Fractional Model Of Tumor Growth And Anticancer Effects Of Mono And Combination Therapies, Kamala Dadashova
H-Discrete Fractional Model Of Tumor Growth And Anticancer Effects Of Mono And Combination Therapies, Kamala Dadashova
Masters Theses & Specialist Projects
In this thesis, we focus on h–discrete and h–discrete fractional representation of a pharmacokinetics-pharmacodynamics (PK-PD) model which describes tumor growth considering time on hNa, where h>0. First, we introduce some definitions, lemmas and theorems on both h–discrete and h–discrete fractional calculus in the preliminary section. In Chapter 3, we work on the PD model with delay by exam ining nabla h–discrete equations and nabla h–discrete fractional equations as well as variation of constants formulas, accordingly. We introduce our model and solve it using theorems we proved in the last section of the indicated chapter. When we do simulation for …