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Addressing Health Disparities In The Rural United States: Advocacy As Caregiving Among Community Health Workers And Promotores De Salud, Ryan I Logan, Heide Castañeda Dec 2020

Addressing Health Disparities In The Rural United States: Advocacy As Caregiving Among Community Health Workers And Promotores De Salud, Ryan I Logan, Heide Castañeda

All publications

Rural populations in the United States are faced with a variety of health disparities that complicate access to care. Community health workers (CHWs) and their Spanish-speaking counterparts, promotores de salud, are well-equipped to address rural health access issues, provide education, and ultimately assuage these disparities. In this article, we compare community health workers in the states of Indiana and Texas, based on the results of two separate research studies, in order to (1) investigate the unique role of CHWs in rural communities and (2) understand how their advocacy efforts represent a central form of caregiving. Drawing on ethnographic, qualitative data—including …


The Effect Of Hope On The Relationship Between Personal And Disease Characteristics And Anxiety And Depression In Adolescents And Young Adults With Cancer, Sharon B. Mcneil Nov 2020

The Effect Of Hope On The Relationship Between Personal And Disease Characteristics And Anxiety And Depression In Adolescents And Young Adults With Cancer, Sharon B. Mcneil

USF Tampa Graduate Theses and Dissertations

Adolescents and young adults (AYAs) with cancer face physical, psychosocial, emotional, and developmental challenges that are unique to their age group. In facing the crisis of a cancer diagnosis, both social support and hope have been shown to be tools utilized by some AYAs. However, AYAs have higher rates of anxiety and depression than in older adults which may have an effect on their levels of hope.

This cross-sectional study examined the mechanistic effects of hope on the relationship between personal characteristics of age, gender, and social support, the disease characteristics of type of cancer and length of time since …


Longitudinal Examination Of A Dual-Factor Model Of Mental Health: Academic Adjustment And Stability Of Group Membership In High School Students In Academically Accelerated Curricula, Letty Langton Dileo Oct 2020

Longitudinal Examination Of A Dual-Factor Model Of Mental Health: Academic Adjustment And Stability Of Group Membership In High School Students In Academically Accelerated Curricula, Letty Langton Dileo

USF Tampa Graduate Theses and Dissertations

Middle adolescence (ages 14 to 18 years old) has been associated with declines in both psychopathology and subjective well-being (SWB). This study examined a dual-factor model (DFM) of mental health, which conceptualizes complete mental health as including both low levels of psychopathology and high levels of SWB, across three time points, each 9-12 months apart, in a sample of 328 9th grade students enrolled in accelerated coursework. This study aimed to determine (1) the stability of students’ mental health status over time, (2) the role of psychopathology versus SWB for students who changed mental health status, and (3) the relationship …


A Review Of American College Campus Tobacco Or Smoke Free Policies: A Case Study Of A Large Urban University, Sarah E. Powell Oct 2020

A Review Of American College Campus Tobacco Or Smoke Free Policies: A Case Study Of A Large Urban University, Sarah E. Powell

USF Tampa Graduate Theses and Dissertations

Objective: A year after a tobacco free policy was passed, the University of South Florida (USF) was interested in the overall policy opinions and efficacy. To assess this a project was completed that included a survey and geospatial data. The survey measured tobacco policy enforcement behavior and a geographic information system (GIS) mapped tobacco policy violation. This project introduces an evaluation process that can efficiently assess an institutions tobacco-free policy. Methods: Using a cross-sectional survey sent to students, faculty, and staff, understanding of policy and resources, tobacco use observations, stage of change regarding policy enforcement, self-efficacy to enforce, and perceived …


On The Importance Of Context: Examining The Applicability Of Infertility Insurance Mandates In The United States Using A Mixed-Methods Study Design, Nathanael B. Stanley Oct 2020

On The Importance Of Context: Examining The Applicability Of Infertility Insurance Mandates In The United States Using A Mixed-Methods Study Design, Nathanael B. Stanley

USF Tampa Graduate Theses and Dissertations

Accessibility of infertility services is disproportionately experienced in the United States. Although there exist state-based health insurance mandates for infertility services, these mandates contain language that disqualify people from using them. In order to better understand why these mandates are not able to reduce the financial burden and bridge the income disparity for using infertility services, the purpose of this study is to add context to the applicability of these insurance mandates through qualitative and quantitative inquiry. Using the Glass and McAtee model of risk regulators as an operational paradigm, this research explores the role of environmental context, or “place”, …


Effects Of The 340b Drug Pricing Program On Hospitals’ Prescribing Behavior, Patient Mix, And Quality Of Care, Yilu Dong Jul 2020

Effects Of The 340b Drug Pricing Program On Hospitals’ Prescribing Behavior, Patient Mix, And Quality Of Care, Yilu Dong

USF Tampa Graduate Theses and Dissertations

In 1992, Congress created the 340B Drug Pricing Program that requires drug manufacturers to provide outpatient drugs to participating hospitals with substantial discounts. Although the intent of the program is to allow covered entities to increase access to care for more vulnerable patients, hospitals are not required by law to pass on the discounts. Therefore, a concern is that hospitals might over-prescribe. This dissertation includes three chapters to study the effects of the 340B program on hospitals’ behavior changes:

Chapter 1 uses state aggregate hospital service spending data from the Centers for Medicare and Medicaid Services (CMS) to study the …


Temporal Discounting And The Assessment And Treatment Of Academic Procrastination, Anthony Concepcion Jul 2020

Temporal Discounting And The Assessment And Treatment Of Academic Procrastination, Anthony Concepcion

USF Tampa Graduate Theses and Dissertations

Many individuals engage in procrastination at some point in their lifetime. Although procrastination is usually not detrimental, for college students, academic procrastination is correlated with adverse health effects (e.g., anxiety, depression, sleep hygiene) and poor academic performance (Akinsola, et al., 2007; Ferrari, et al., 1995). Furthermore, the prevalence of academic procrastination is high with reports of up to 95% of college students engaging in detrimental amounts of procrastination (Hussain & Sultan, 2010). Notably, students enrolled in online courses are likely to be at greater risk to experience adverse consequences associated with procrastination (Elvers, et al, 2003). Previous studies have focused …


Evaluating Public Posting, Goal Setting, And Rewards To Increase Physical Activity In Children, Bryon G. Miller Jul 2020

Evaluating Public Posting, Goal Setting, And Rewards To Increase Physical Activity In Children, Bryon G. Miller

USF Tampa Graduate Theses and Dissertations

In Experiments 1 and 2 we evaluated a pedometer-based intervention consisting of public posting between two teams of students, with additional self-monitoring, goal setting, and reinforcement components, to increase physical activity during school recess. In the absence of self-monitoring, performance feedback alone did not increase physical activity levels above those observed during baseline. Additionally, higher levels of physical activity were observed when goal-setting was introduced, with the highest levels of activity observed when raffle tickets could be earned for exceeding a specified step-total goal. In Experiment 3 we removed the team component and evaluated similar intervention components across an entire …


Using Observations From The Uaw-Ford Ergonomic Assessment Tool To Predict Distal Upper Extremity Musculoskeletal Disorders, Zachariah T. Brandes-Powell Jun 2020

Using Observations From The Uaw-Ford Ergonomic Assessment Tool To Predict Distal Upper Extremity Musculoskeletal Disorders, Zachariah T. Brandes-Powell

USF Tampa Graduate Theses and Dissertations

Distal upper extremity (DUE) musculoskeletal disorders (MSDs) affect thousands of workers annually. Job tasks can have a significant amount of MSD risk depending on the presence of certain risk factors The UAW-Ford Ergonomic Surveillance Tool (EST) is a method specifically designed for the UAW and Ford Motor Company to assess MSD risk in its facilities. The purpose of this report is to evaluate which risk factors in the UAW-Ford EST predict the risk of developing DUE MSDs. Data collected by a previous study on four UAW-Ford automotive manufacturing plants were analyzed. Target jobs were selected based on associated First Time …


Enhancing Intergenerational Conversation Using Visual Cues: Effects Of A Historical Timeline, Allyson Lindsay Jun 2020

Enhancing Intergenerational Conversation Using Visual Cues: Effects Of A Historical Timeline, Allyson Lindsay

USF Tampa Graduate Theses and Dissertations

Interacting with individuals with expressive aphasia can be particularly challenging not only because of the language impairments, but also because of the frequent age difference between the clients with aphasia and student clinicians. Although students learn a variety of strategies to support language impairments, there remains a need to bridge the age gap in historical knowledge to enhance conversation. The current study explored the use of a timeline as written and pictorial cue to support conversations between individuals with aphasia and students. This study consisted of Two Experiments. The purpose of Experiment 1 was to identify the differences in knowledge …


Using Observations From The Uaw-Ford Ergonomic Assessment Tool To Predict Low Back Musculoskeletal Disorders, Colins Nwafor Jun 2020

Using Observations From The Uaw-Ford Ergonomic Assessment Tool To Predict Low Back Musculoskeletal Disorders, Colins Nwafor

USF Tampa Graduate Theses and Dissertations

Musculoskeletal disorders of the low back are common injuries found in many work environments. Some of the risk factors that workers experience include the weight of object being lifted during a task, frequency, duration, posture, distance the object is lifted, how well the worker can grasp the object, and the degree to which the worker may have to twist and turn their body during a lift. There are many tools that have been developed that are used to assess risk of a worker developing low back pain. The purpose of this study is to determine if the UAW-Ford Ergonomic Surveillance …


Aligning Voice And Communication With Identity – A Survey On Transgender And Gender Diverse Populations, Rachel T. Chalom Jun 2020

Aligning Voice And Communication With Identity – A Survey On Transgender And Gender Diverse Populations, Rachel T. Chalom

USF Tampa Graduate Theses and Dissertations

Purpose: This research has two goals. The first goal is to examine transgender (TG) and gender diverse (GD) voice and communication functioning and the impact of voice on their everyday lives. The second goal is to examine the knowledge, attitudes, and beliefs speech-language pathologists (SLP) have about the TG and GD community and to investigate the relationship between self- and listener-perception and its correspondence to quality of life (QoL).

Methods: A total of 59 participants took part in this research. The research was separated into two parts, the first included 24 TG and GD individuals who participated in a Qualtrics …


The Role Of Threat And Efficacy In Anti-Vaping Ads: A Test Of The Extended Parallel Process Model, Ryan Noone Jun 2020

The Role Of Threat And Efficacy In Anti-Vaping Ads: A Test Of The Extended Parallel Process Model, Ryan Noone

USF Tampa Graduate Theses and Dissertations

Often thought of as a safer alternative to traditional cigarettes, electronic cigarette use among youth and young adults has steadily increased over the past 10 years. With over 34 percent of high school students and over 7.8 percent of young adults using electronic cigarettes, organizations like the CDC and the FDA have created campaigns and advertisements to combat the epidemic (Truth Initiative). This study uses a 2x2 between subject factoral experiment to gain insights into how varying levels of anti-vaping advertisements’ threat and efficacy elements effect college age students’ perceptions and behaviors towards e-cigarettes. While several of the study’s hypotheses …


Impact Of Heat-Related Illness And Natural Environments On Behavioral Health Related Emergency And Hospital Utilization In Florida, Natasha Kurji Jun 2020

Impact Of Heat-Related Illness And Natural Environments On Behavioral Health Related Emergency And Hospital Utilization In Florida, Natasha Kurji

USF Tampa Graduate Theses and Dissertations

Behavioral health disorders are the leading cause of disability in the United States and are known to have multidimensional effect on wellbeing. Several environmental factors are known to impact behavioral health such as weather (i.e. heat) and access to natural environments (i.e. parks and beaches). The study goals were to identify contextual factors that increase the co-occurrence of heat-related illness and behavioral health disorders, illustrate the re-utilization patterns of these co-occurring cases in Florida emergency and inpatient settings, and explore the association between behavioral health disorders such as anxiety and depression, and natural environments such as parks and beaches. The …


Nurses And Needlesticks: Perceptions Of Stigma And Hiv Risk, Bethany Sharon Moore Jun 2020

Nurses And Needlesticks: Perceptions Of Stigma And Hiv Risk, Bethany Sharon Moore

USF Tampa Graduate Theses and Dissertations

Health-care providers (HCPs) are vulnerable to occupational health hazards, including dirty needle-stick injuries (DNSIs), which increase the risk for infection with HIV and other blood-borne pathogens. This study examines the perceptions of nurses and nurse practitioners who work in various health care settings regarding HIV-risk and DNSIs, in order to ascertain how these perceptions inform their decision-making regarding their health and nursing practice. I utilize a phenomenological approach to analyze the lived reality and embodiment of the DNSI experience by HCPs. The study explores the personal and institutional level factors that may influence the timely reporting and treatment of DNSIs, …


‘It’S Been A Huge Stress’: An In-Depth, Exploratory Study Of Vaccine Hesitant Parents In Southern California, Mika Kadono May 2020

‘It’S Been A Huge Stress’: An In-Depth, Exploratory Study Of Vaccine Hesitant Parents In Southern California, Mika Kadono

USF Tampa Graduate Theses and Dissertations

In 2015, the US experienced a widespread measles outbreak that originated at Disneyland, California and spread to six other states, Mexico, and Canada. That year, California passed Senate Bill 277 (SB 277), which eliminated the personal belief exemption for vaccinations required for school entry; California became the third state in the country to eliminate nonmedical exemptions. In 2019, Washington, Maine, and New York followed suit eliminating all nonmedical exemptions amid the largest measles outbreak in the US in 25 years. Many countries, including the US, are experiencing a rise in vaccine preventable diseases due, in part, to increasing vaccine hesitancy, …


Social Exclusion Of Older Mossi Women Accused Of Witchcraft In Burkina Faso, West Africa, Clarisse Barbier May 2020

Social Exclusion Of Older Mossi Women Accused Of Witchcraft In Burkina Faso, West Africa, Clarisse Barbier

USF Tampa Graduate Theses and Dissertations

Among the most marginalized populations in the world, one group of women has been persistently ignored, silenced, and forgotten. In Burkina Faso, West Africa, older women in rural villages are often the target of witchcraft accusations; the consequences of these accusations are alarming because these women undergo violent attacks, face exclusion from their villages, and become the most vulnerable and marginalized segment of the Burkinabe population. Between August 2017 and November 2018, I conducted an ethnographic study of Burkinabe women accused of witchcraft living in two shelters in the capital city of Ouagadougou and examined women’s experiences of accusation, trauma, …


“They Will Think We Are The Cancer Family”: Studying Patterns Of Cancer Disclosure And Communication Among Indian Immigrants In The United States, Kanan Mehta Apr 2020

“They Will Think We Are The Cancer Family”: Studying Patterns Of Cancer Disclosure And Communication Among Indian Immigrants In The United States, Kanan Mehta

USF Tampa Graduate Theses and Dissertations

Studies of Indian immigrants in Western countries show that the rates of cancer increase significantly within a generation in the host country. The negative social perceptions associated with health outcomes of cancer often perpetuate limited disclosure regarding the diagnosis of cancer among patients and families. This can result in disrupted communication in clinical settings, while causing increased stress among patients and caregivers. These findings demonstrate the need for studying lived experiences of cancer-related illness and its impacts on social relationships in the domestic and public sphere.

This study explored cancer disclosure and communication among Indian immigrants in the United States …


Differences In Knowledge Acquisition, Perceived Engagement And Self-Efficacy In Latino Promotores Delivering The Heart Disease Prevention Program Su Corazόn, Su Vida, Samuel Matos-Bastidas Apr 2020

Differences In Knowledge Acquisition, Perceived Engagement And Self-Efficacy In Latino Promotores Delivering The Heart Disease Prevention Program Su Corazόn, Su Vida, Samuel Matos-Bastidas

USF Tampa Graduate Theses and Dissertations

Su Corazόn, Su Vida (Your Heart, Your Life) is a community-based, small-group health intervention designed to empower Latinos to enhance cardiovascular disease awareness and initiate enduring lifestyle changes to improve health outcomes and quality of life. Originally developed to be delivered in weekly sessions in Spanish or English language, it addresses several heart disease risk factors including unhealthy eating habits, poor physical activity, high cholesterol, overweight, metabolic syndrome, diabetes and tobacco smoking, among others. Instructors use diverse learning and support strategies such as group discussion, role modeling, problem-solving, health action planning, and self-monitoring. Participants help each other to stay on …


Governmentality, Biopower, And Sexual Citizenship: A Feminist Examination Of Sexual And Reproductive Healthcare Experiences Of 18-24 Year-Olds In The U.S. Southeast, Melina K. Taylor Mar 2020

Governmentality, Biopower, And Sexual Citizenship: A Feminist Examination Of Sexual And Reproductive Healthcare Experiences Of 18-24 Year-Olds In The U.S. Southeast, Melina K. Taylor

USF Tampa Graduate Theses and Dissertations

Sexual and reproductive healthcare in the U.S. is a contentious and often stigmatized topic. Conservative politics and Christian religious ideology guide laws and policies that inform narratives of sexual citizenship that promote white, heterosexual, procreative, cis-gendered relationships as the ideal. For young people, exposure to sexuality education greatly influences their self-identity as sexual citizens and guides how they form intimate relationships. While sexual and reproductive healthcare has been included marginally in the discipline of anthropology, almost no research has focused on young people’s sexual and reproductive healthcare within the U.S.

This dissertation examines the viewpoints and experiences of 18-24 year-old …


The Role Of Financial Insecurity And Expectations On Perspectives Of Mental Health Services Among Refugees, Jacqueline M. Siven Feb 2020

The Role Of Financial Insecurity And Expectations On Perspectives Of Mental Health Services Among Refugees, Jacqueline M. Siven

USF Tampa Graduate Theses and Dissertations

This dissertation examines how perspectives of mental health among refugees are situated within the realities of the refugee resettlement system, a population for which information on this issue is quite limited. Through in-depth interviews and participant observation with Congolese refugees and non-Congolese refugee-serving professionals in a major Florida city, this dissertation examines how perceptions of mental health and mental health services among refugees were affected by financial insecurity and disparities in expectations. Local Congolese refugees expected the American Dream; they believed that once they arrived they would find prosperity through hard work. Instead they experienced frustration and distress because the …


Exploration Of Factors Associated With Perceptions Of Community Safety Among Youth In Hillsborough County, Florida: A Convergent Parallel Mixed-Methods Approach, Yingwei Yang Feb 2020

Exploration Of Factors Associated With Perceptions Of Community Safety Among Youth In Hillsborough County, Florida: A Convergent Parallel Mixed-Methods Approach, Yingwei Yang

USF Tampa Graduate Theses and Dissertations

Introduction: Youth perceived safety is not only linked to crime and violence in a neighborhood but is also associated with health risk behaviors and certain neighborhood characteristics. The purpose of this mixed-methods study was to measure the co-occurring effects of individual and community risk factors by conducting a secondary data analysis using structural equation modeling (SEM) and to explore reasons for youth feeling safe/unsafe in their community using photovoice methodology.

Methods: Syndemic theory/model served as the theoretical framework to guide this mixed-methods study with a convergent parallel design. The quantitative strand (first manuscript) utilized an existing dataset collected from middle …


Adolescent Asthma And School Disparities: An Ecological Perspective Of Students And Stakeholders, Tali Schneider Jan 2020

Adolescent Asthma And School Disparities: An Ecological Perspective Of Students And Stakeholders, Tali Schneider

USF Tampa Graduate Theses and Dissertations

Asthma is a chronic condition that mainly affects adolescents. Recent reports from the Centers for Disease Control and Prevention (CDC) indicate a gradual increase in rates of lifetime asthma among adolescents from 17.1% in 2005 to 22.8% in 2015. Currently, one in ten adolescents nation-wide experience active asthma; similar trends are seen in the state of Florida (Florida Asthma Program, 2013; Centers for Disease Control and Prevention, Prevention, 2015). As a chronic, lifelong condition, asthma can be life-threatening if not properly controlled. When exacerbated, attacks of asthma constrict airways, leading to restrained breathing, wheezing, coughing and chest pain (Parulekar, Alobaidy, …


Effects Of Learning A Second Language On English Academic And Low-Frequency Vocabulary Acquisition And Metalinguistic Knowledge, Hayriye Karliova Jan 2020

Effects Of Learning A Second Language On English Academic And Low-Frequency Vocabulary Acquisition And Metalinguistic Knowledge, Hayriye Karliova

USF Tampa Graduate Theses and Dissertations

This study compared the possible effects of learning a language from the Italic branch of the Indo-European language family as a second language (L2), namely Latin and Spanish, on English academic and low-frequency vocabulary acquisition and metalinguistic knowledge of native English speaker (NES) undergraduates in their first language (L1), English.

The study sought to attain two objectives: first, it aimed to discover the effects of learning Latin and Spanish as L2s with respect to the vocabulary acquisition of NES undergraduates; second, it aimed to detect the effects these L2s in terms of metalinguistic awareness. In both cases, the focus was …


Survey Of Histoplasma Capsulatum In Bat Guano And Status Of Histoplasmosis In Slovenia, Central Europe, Janez Mulec, Saša Simčič, Tadeja Kotar, Romina Kofol, Sanja Stopinšek Jan 2020

Survey Of Histoplasma Capsulatum In Bat Guano And Status Of Histoplasmosis In Slovenia, Central Europe, Janez Mulec, Saša Simčič, Tadeja Kotar, Romina Kofol, Sanja Stopinšek

International Journal of Speleology

There have been increasing reports on the presence of Histoplasma capsulatum in some European countries. The study investigated the presence of Histoplasma in bat guanos, speleologists with records of visiting Histoplasma-endemic regions and patients with histoplasmosis. A commercial ALPHA Histoplasma Antigen enzyme immunoassay was tested as an alternative methodology to detect Histoplasma in environment and compared with polymerase chain reaction (PCR) assays. The presence of Histoplasma antigen in bat guanos was not confirmed by PCR. Among 14 healthy speleologists, two were indicated as having the Histoplasma antigen in urine, but expressed negative PCR-specific results for the Histoplasma antigen. Five …


The Impact Of Covid-19 On Hiv Treatment And Research: A Call To Action, Tiffany Chenneville, Kemesha Gabbidon, Patricia Hanson, Cashea Holyfield Jan 2020

The Impact Of Covid-19 On Hiv Treatment And Research: A Call To Action, Tiffany Chenneville, Kemesha Gabbidon, Patricia Hanson, Cashea Holyfield

USF St. Petersburg campus Faculty Publications

The impact of the COVID-19 pandemic is far reaching, with devastating effects on individuals, communities, and societies across the world. People with chronic health conditions may be at greater risk of contracting or experiencing complications from COVID-19. In addition to illness or death for those who contract the virus, the physical distancing required to flatten the curve of new cases is having a negative impact on the economy, the effects of which intersect with mental health and other existing health concerns, thus affecting marginalized communities. Given that HIV also has a disproportionate impact on marginalized communities, COVID-19 is affecting people …


Influence Of Cigarettes And Alcohol On The Severity And Death Of Covid-19: A Multicenter Retrospective Study In Wuhan, China, Mengyuan Dai, Liyuan Tao, Zhen Chen, Zhi Tian, Xiaofang Guo, Diane S Allen-Gipson, Ruirong Tan, Rui Li, Li Chai, Fen Ai, Miao Liu Jan 2020

Influence Of Cigarettes And Alcohol On The Severity And Death Of Covid-19: A Multicenter Retrospective Study In Wuhan, China, Mengyuan Dai, Liyuan Tao, Zhen Chen, Zhi Tian, Xiaofang Guo, Diane S Allen-Gipson, Ruirong Tan, Rui Li, Li Chai, Fen Ai, Miao Liu

All publications

Background: The recent emergence and rapid global spread of coronavirus disease 2019 (COVID-19) is leading to public health crises worldwide. Alcohol consumption and cigarette smoking (CS) are two known risk factors in many diseases including respiratory infections.

Methods: We performed a multi-center study in the four largest hospitals designated for COVID-19 patients in Wuhan. There are totally 1547 patients diagnosed with COVID-19 enrolled in the study, alcohol consumption and CS history were evaluated among these patients. The epidemiology, laboratory findings and outcomes of patients contracted COVID-19 were further studied.

Results: Our findings indicated that COVID-19 patients with a history of …


Safety And Efficacy Of Tocilizumab In The Treatment Of Severe Acute Respiratory Syndrome Coronavirus-2 Pneumonia: A Retrospective Cohort Study, Atul Patel, Kinjal Shah, Mitkumar Dharsandiya, Ketan Patel, Tushar Patel, Mukesh Patel, Tea Reljic, Ambuj Kumar Jan 2020

Safety And Efficacy Of Tocilizumab In The Treatment Of Severe Acute Respiratory Syndrome Coronavirus-2 Pneumonia: A Retrospective Cohort Study, Atul Patel, Kinjal Shah, Mitkumar Dharsandiya, Ketan Patel, Tushar Patel, Mukesh Patel, Tea Reljic, Ambuj Kumar

All publications

Background: Cytokine release storm (CRS) in severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) is thought to be the cause for organ damage and death which is independent of the actual viral burden. Tocilizumab (TCZ), an interleukin-6 receptor antagonist, is approved for the treatment of CRS. We describe the efficacy and safety of TCZ in SARS CoV-2 pneumonia. Methods: This retrospective study was conducted at a tertiary care hospital from April 20 2020 to May 21 2020. The primary endpoint was the cumulative incidence of a composite of either need for admission to the intensive care unit (ICU) with invasive mechanical …


Why Covid-19 Transmission Is More Efficient And Aggressive Than Viral Transmission In Previous Coronavirus Epidemics?, Fatma Elrashdy, Elrashdy M. Redwan, Vladimir N. Uversky Jan 2020

Why Covid-19 Transmission Is More Efficient And Aggressive Than Viral Transmission In Previous Coronavirus Epidemics?, Fatma Elrashdy, Elrashdy M. Redwan, Vladimir N. Uversky

Molecular Medicine Faculty Publications

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing a pandemic of coronavirus disease 2019 (COVID-19). The worldwide transmission of COVID-19 from human to human is spreading like wildfire, affecting almost every country in the world. In the past 100 years, the globe did not face a microbial pandemic similar in scale to COVID-19. Taken together, both previous outbreaks of other members of the coronavirus family (severe acute respiratory syndrome (SARS-CoV) and middle east respiratory syndrome (MERS-CoV)) did not produce even 1% of the global harm already inflicted by COVID-19. There are also four other CoVs capable of infecting humans …


Why Covid-19 Transmission Is More Efficient And Aggressive Than Viral Transmission In Previous Coronavirus Epidemics?, Fatma Elrashdy, Elrashdy M. Redwan, Vladimir N. Uversky Jan 2020

Why Covid-19 Transmission Is More Efficient And Aggressive Than Viral Transmission In Previous Coronavirus Epidemics?, Fatma Elrashdy, Elrashdy M. Redwan, Vladimir N. Uversky

Molecular Medicine Faculty Publications

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing a pandemic of coronavirus disease 2019 (COVID-19). The worldwide transmission of COVID-19 from human to human is spreading like wildfire, affecting almost every country in the world. In the past 100 years, the globe did not face a microbial pandemic similar in scale to COVID-19. Taken together, both previous outbreaks of other members of the coronavirus family (severe acute respiratory syndrome (SARS-CoV) and middle east respiratory syndrome (MERS-CoV)) did not produce even 1% of the global harm already inflicted by COVID-19. There are also four other CoVs capable of infecting humans …