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Genomics And Transcriptomics Approaches To Understanding Drug Resistance Mechanisms In The Malaria Parasite Plasmodium Falciparum, Justin Allan Gibbons
Genomics And Transcriptomics Approaches To Understanding Drug Resistance Mechanisms In The Malaria Parasite Plasmodium Falciparum, Justin Allan Gibbons
USF Tampa Graduate Theses and Dissertations
The malaria parasite Plasmodium falciparum is responsible for about 500,000 deaths a year and is evolving resistance to the front-line treatment of artemisinin-based combination therapy. Resistance is currently confined to South East Asia, however millions of lives will be at risk if resistance spreads to Africa. Understanding the mechanism of resistance to artemisinins would aid containment strategies to prevent the spread of artemisinin resistance. There is also an urgent need to accelerate drug discovery since drug resistance has already been documented to all existing antimalarials. Here, I report on our efforts to understand the function of the gene k13, the …
Essays In Applied Microeconomics, Lijuan Feng
Essays In Applied Microeconomics, Lijuan Feng
USF Tampa Graduate Theses and Dissertations
Chapter 1 studies the effect of body weight on labor market outcomes. Using longitudinal data from the China Health and Nutrition Survey (CHNS) from 1989 to 2011, and both instrumental variable and fixed effects estimation to control for the endogeneity of body weight, I examine the wage effect of BMI by gender, type of residence area, and occupation. Results from linear OLS regression show a positive relationship between body weight and income for males in both rural and urban areas and females in rural areas, while a negative one for females in urban areas. After controlling for the unobserved individual …