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Ampk: A Balancer Of The Renin–Angiotensin System, Jia Liu, Xuan Li, Qingguo Lu, Di Ren, Xiaodong Sun, Thomas Rousselle, Ji Li, Jiyan Leng
Ampk: A Balancer Of The Renin–Angiotensin System, Jia Liu, Xuan Li, Qingguo Lu, Di Ren, Xiaodong Sun, Thomas Rousselle, Ji Li, Jiyan Leng
Surgery Faculty Publications
The renin–angiotensin system (RAS) is undisputedly well-studied as one of the oldest and most critical regulators for arterial blood pressure, fluid volume, as well as renal function. In recent studies, RAS has also been implicated in the development of obesity, diabetes, hyperlipidemia, and other diseases, and also involved in the regulation of several signaling pathways such as proliferation, apoptosis and autophagy, and insulin resistance. AMP-activated protein kinase (AMPK), an essential cellular energy sensor, has also been discovered to be involved in these diseases and cellular pathways. This would imply a connection between the RAS and AMPK. Therefore, this review serves …
Factors Associated With Chest Tube Placement In Blunt Trauma Patients With An Occult Pneumothorax, Michael Paplawski, Swapna Munnangi, Jody C. Digiacomo, Edwin Gonzalez, Ashley Modica, Shawndeep S. Tung, Catherine Ko
Factors Associated With Chest Tube Placement In Blunt Trauma Patients With An Occult Pneumothorax, Michael Paplawski, Swapna Munnangi, Jody C. Digiacomo, Edwin Gonzalez, Ashley Modica, Shawndeep S. Tung, Catherine Ko
Surgery Faculty Publications
Background. An occult pneumothorax is identified by computed tomography but not visualized by a plain film chest X-ray. The optimal management remains unclear. Methods. A retrospective review of an urban level I trauma center’s trauma registry was conducted to identify patients with occult pneumothorax over a 2-year period. Factors predictive of chest tube placement were identified using univariate and multivariate logistic regression analysis. Results. A total of 131 patients were identified, of whom 100 were managed expectantly with an initial period of observation. Ultimately, 42 (32.0%) patients received chest tubes and 89 did not. The patients who …
Observations On Multi-Generational Interactions In Academic Surgical Practice And Rducation, Fernando A. M. Herbella, Vic Velanovich
Observations On Multi-Generational Interactions In Academic Surgical Practice And Rducation, Fernando A. M. Herbella, Vic Velanovich
Surgery Faculty Publications
No abstract provided.
Review Of Procedures For Reconstruction Of Soft Tissue Chest Wall Defects Following Advanced Breast Malignancies, Alicia Billington, Deniz Dayicioglu, Paul Smith, John Kiluk
Review Of Procedures For Reconstruction Of Soft Tissue Chest Wall Defects Following Advanced Breast Malignancies, Alicia Billington, Deniz Dayicioglu, Paul Smith, John Kiluk
Surgery Faculty Publications
The purpose of this article is to review closure options for complex chest wounds in patients with locally advanced breast cancer. Experiences of the plastic and oncologic surgery teams at Moffitt Cancer Center were reviewed, and the literature researched for various surgical options of complex chest wound closure. Multiple treatment modalities exist for reconstruction of complex chest wall wounds with the external oblique and V-Y latissimus dorsi musculocutaneous advancement flaps serving as workhorses in reconstruction. Treatment of cancer has moved from simply a surgical solution to include other modalities such as hormonal therapy, chemotherapy, and radiation—the latter 2 having serious …