Digital Commons Network^™

The Development Of Hyaluronan-Based Contract Agents For The Intraoperative Detection Of Pancreatic Tumors, Bowen Qi

Theses & Dissertations

Pancreatic ductal adenocarcinoma is highly lethal and surgical resection is the only potential curative treatment for the disease. Tumor-specific intraoperative fluorescence imaging could improve staging and surgical resection, thereby improving prognosis. In the first study, hyaluronic acid derived NPs with physico-chemically entrapped indocyanine green, termed NanoICG, were utilized for intraoperative near infrared fluorescence detection of pancreatic cancer. NanoICG accumulated significantly in an orthotopic pancreatic ductal adenocarcinoma model with safety profile both in vitro and in vivo. To maximize tumor signal, while minimizing signal in healthy pancreas and RES capture of macromolecules, in the next study, we describe the rational …

Orthodontically Induced External Root Resorption In Extraction Versus Non-Extraction Treatment Modalities – A Retrospective Cone-Beam Computed Tomography (Cbct) Study, Jaykishan Patel

Theses & Dissertations

Purpose of this study was to evaluate orthodontically induced external apical root resorption using cone beam computed tomography in patients receiving orthodontic treatment with or without extractions. Records of 188 consecutively treated patients who received orthodontic treatment with or without extractions were evaluated. Pre-and post-treatment root lengths of maxillary incisors, volumes of maxillary central incisors, and apex displacement of either right or left maxillary central incisors were measured using Invivo 5.4 or ITK-SNAP 3.8.0 software. After adjusting for initial length, treatment duration, tooth, sex, race, bracket type, and malocclusion, maxillary incisor reduction of root length in extraction group was 0.37 …

Gender Difference In Glenoid Remodeling, Kent Rinehart, Matt Teusink, Chris Peters, Ann Zajicek

Graduate Medical Education Research Journal

No abstract provided.

Comparison Of Post-Operative Outcomes Of Ciprofloxacin Otic Suspension Versus Ciprofloxacin-Dexamethasone Otic Drops In Myringotomy With Tube Placement, Andrew W. Logeman, Daniel V. Arkfeld, Jayme R. Dowdall, Dwight T. Jones

Graduate Medical Education Research Journal

No abstract provided.

Patterns Of Opiate Use And Prescription Practices In Isolated Orthopedic Trauma Injuries: Creating Guidelines, Matthew Mormino, Justin Sieber, Sara Putnam, David Kusin, Zachary Bailey, Todd Gilbert, Emmett Gannon, Josh Locker, Matthew Tingle, Matthew Freeman, Mark Amirtharaj

Graduate Medical Education Research Journal

No abstract provided.

Bmi As A Risk Factor For Early Dislocation Of Total Shoulder Arthroplasty, David J. Kusin, Joshua A. Ungar, Kaeli K. Samson, Matthew J. Teusink

Graduate Medical Education Research Journal

No abstract provided.

Do Pre-Operative Emotional And Mental Rand Sf-36 Scores Predict Outcomes After Total Hip And Knee Arthroplasty?, Erik Bowman, Curtis Hartman, Kevin Garvin, Beau Konigsberg, Liz Lyden, Seth Wardyn

Graduate Medical Education Research Journal

No abstract provided.

Three Cases Of Laryngeal Histoplasmosis In The Midwestern United States, Jonathan Blecha, Christopher Bingcang, Justin Oltman

Graduate Medical Education Research Journal

No abstract provided.

University Of Nebraska Medical Center Pressure Ulcer Prevention Initiative, Stephan Barrientos, Maria Tecos, Kaeli Samson, Lynette Smith, Chandrakanth Are, Perry Johnson, Jason Miller, Debra Reilly

Graduate Medical Education Research Journal

No abstract provided.

A Case Of Monocytic Pleocytosis In West Nile Neuroinvasive Disease, Brian Villafuerte Trisolini, Mohamed Taha, Maryam Matloub, Thomas Diesing

Graduate Medical Education Research Journal

No abstract provided.

Risk Of Sleep Disorders In Hospitalized Patients With Obstructive Lung Disease: An Observational Study, Nancy H. Stewart, Ryan Walters, Babak Mokhlesi, Diane Lauderdale, Vineet M. Arora

Graduate Medical Education Research Journal

No abstract provided.

The Financial Burden Of The Urology Match: Room For Improvement, Jinfeng Jiang, Joshua S. Engelsgjerd, Chad A. Lagrange, Christopher M. Deibert

Graduate Medical Education Research Journal

Abstract

Introduction/ Background – The Urology match remains highly competitive, but there is limited published data on the costs of the application process for contemporary applicants. This study aims to determine the financial burden of the Urological match and the effect it has on applicants.

Methods/ Materials – All applicants to the University of Nebraska Medical Center (UNMC) Urology Residency in the 2019 Urology match were invited to complete an anonymous, IRB approved online survey containing 16 questions on interview travel and costs, financial aid, and debt burden.

Results – Thirty-nine out of 183 (21%) applicants responded to the survey. …

Long Term Outcomes Of Surgical And Clinical Symptoms Following Minimally Invasive Heller Myotomy: A Retrospective Clinical Database Review, Laura E. Flores, Priscila Rodrigues Armijo, Bhavani Pokala, Sarah Samreen, Dmitry Oleynikov

Graduate Medical Education Research Journal

I

Introduction

Minimally invasive Heller myotomy rates have increased, but little evidence is available regarding long term clinical and surgical outcomes. Our aim was to evaluate long term symptom improvement and medication resolution for patients undergoing minimally invasive Heller myotomy.

Methods

A single-institution database was retrospectively reviewed for patients undergoing laparoscopic Heller myotomy (LHM) or robotic Heller myotomy (RHM) during 2007-2018. Patients with primary HM followed by a Dor fundoplication were included. Demographics and surgical data were analyzed. Esophageal symptoms, testing, and medication use were collected preoperatively (pre-op), at 6-month (6-mo), 12-month (12-mo), and long-term (LT; 12-mo+) follow-up. Analysis was …

Comprehensive Chronic Pain Treatment: Does Smoking Affect Outcomes?, Jamison Hofer, David Cates, Valerie K. Shostrom, Brendan Thelen, Kimberley Haynes-Henson

Graduate Medical Education Research Journal

Abstract

Objective: To determine whether smoking status effects pain and functional outcomes in a chronic pain program.

Methods: A retrospective cohort study of 178 patients treated at the Nebraska Medicine comprehensive Pain Management Program over a five year period was completed. Outcomes measures were the Visual Analog Scale Past Month Average Pain score (VAS-PMA), Multidimensional Pain Inventory pain and interference scales (MPI-P and MPI-I), and the Pain and Impairment Relationship Scale (PAIRS). Patients were categorized by smoking status into non-smoker or current smoker groups. Wilcoxon tests were used to compare the pre scores, post scores, and post-minus-pre scores between smoking …

A Retrospective Study At Two Level One Trauma Centers On The Association Of Internal Injuries With Femoral Fractures, Ryan E. Miller, Catherine Olinger, Leonid Grossman, Dennis Chakkalakal, Karl Bergmann, Elizabeth Lyden, Justin Siebler

Graduate Medical Education Research Journal

Abstract: Injuries capable of fracturing the femur often involve concurrent internal organ damage. However, up to 25% of injuries are initially missed. Prior studies evaluating the association of femur fractures with internal injury included only automobile trauma, were skewed toward more severe injuries, and were broad database studies. To our knowledge, there are no studies of this kind that include bicycle, motorcycle, and motor vehicle-pedestrian trauma, excluding those deceased at the scene, and which included chart reviews. We hypothesized that in the trauma setting, the presence of a femur fracture would correlate with an increase in concomitant internal organ injuries. …

Influence Of Health Habits On The Success Of The Community Response Program, Hannah Harrington

Capstone Experience

The goal of this project is to determine how specific health habits can affect success of the Community Response (CR) program. Community Response is a program that brings government, non-profit and faith-based organizations together in one community to share resources, identify challenges and create solutions with the goal of strengthening the protective factors that help families raise happy, healthy children (Lift Up Sarpy County, 2018). Health habits include habits centered around everyday life including protective factors such as maintaining support systems, financial stability, and other ways to strengthen families, eliminate risk, and keep children out of the child welfare system. …

Trends Of Endometrial Cancer Among Adult Women In The United States, Fnu Kanishka

Capstone Experience

Background: Endometrial cancer also referred to as uterine corpus cancer is the fourth most common cancer diagnosed among US women. It is also one of the few cancers in the US that has an increasing incidence and mortality rate. This study examined the overall and race specific age-adjusted incidence rate as well as incidence-based mortality rate of endometrial cancer in the United States from 1975-2016.

Methods: Surveillance, Epidemiology, and End Results (SEER) 1975-2016 data were used. Overall and race specific age-adjusted incidence rate, incidence-based mortality rates and 95% confidence intervals were calculated Trend graphs were created, annual average percent change …

Association Between Gastroduodenal Ulcer And Age Of Diagnosis Of Head And Neck, Gastroduodenal And Pancreatic Cancer, Rukevwe Madusor

Capstone Experience

Background: Cancer is the second leading cause of death in the United States and remains a major public health problem worldwide. Epidemiological studies have demonstrated that insulin like growth factor-1 (IGF-1) is linked to ulcers and most cancers. Although studies have investigated the role of IGF1 in ulcer healing and cancer pathogenesis, the link between ulcer and cancer remains unclear. Hence, we assessed the relationship between ulcers and cancers.

Methods: This study consists of a sample of 180 cancer patients obtain by convenience sampling who were seen at Nebraska Medicine and were enrolled in the integrated cancer repository for cancer …

Evaluating Occupational Hazards And Personal Protective Equipment Use On Farms In Kyrgyzstan, Christopher Tougeron, Chandran Achutan, Kenesh Dzhusupov, Lorena Baccaglini

Capstone Experience

Objectives – The purpose of this study was to identify occupational hazards and personal protective equipment use on farms operating in Kyrgyzstan.

Methods – We recruited 20 farmers in Kyrgyzstan. They completed a questionnaire and responded to interview questions to determine their occupational hazards, personal protective equipment use, and work-related injuries. We measured noise levels using the National Institute for Occupational Safety and Health sound level meter application for Apple iOS.

Results – Most farmers reported knowing how and when to use personal protective equipment, however 95 percent had not received training on how to use them. Observation of farmers …

Age-Adjusted Incidence Rates And Time Trends Of Non-Hodgkin Lymphoma By Subtype, 2000-2015, Daitrang Le

Capstone Experience

Background: Non-Hodgkin lymphomas (NHL) are a group of diverse and complex cancers of the lymphocytes. More than 60 subtypes have been identified based on certain characteristics of the cancer cell. The objectives of this study were to: 1) determine NHL age-adjusted incidence rates from 2000 to 2015 in the U.S. by age, sex, and race/ethnicity; 2) to examine age-adjusted subtype-specific NHL incidence rates by age, sex, and race/ethnicity; 3) to determine if there was significant time trend in age-adjusted NHL incidence rate from 2000-2015 in the U.S by age, sex, and race/ethnicity.; 4) and to examine time trend in age-adjusted …

The Association Between Melanoma And Exposure To Arsenic Among U.S. Adults Using The National Health And Nutrition Examination Survey (Nhanes) From 2003 To 2016, Ahmed Bedaiwi

Capstone Experience

Background: Melanoma is a deadly skin cancer at late stages, and its incidence has been increasing significantly over the last ten years in the United States. Chronic exposure to arsenic has been associated in many studies as a risk factor for non-melanoma skin cancer, notably squamous cell carcinoma. However, current knowledge is limited regarding melanoma and long-term arsenic exposure.

Methods: We conducted a cross-sectional study using the 2003-2016 cycles of the National Health and Nutrition Examination Survey (NHANES), to investigate the association between arsenic exposure and self-reported melanoma and non-melanoma skin cancer diagnoses. Univariate and multivariate logistic regressions were conducted. …

Enhancing Scholarly Productivity Among Physical Therapy Faculty Through Professional Networks, Betsy J. Becker, Gilbert Willett, Victoria Kennel

Posters and Presentations: Physical Therapy

Purpose

Let's build a talented workforce of physical therapy educators with diverse ideas who collaborate on projects and discover new knowledge! Faculty are the educational leaders in physical therapy. With growing demands on workload and time, it is essential to attract talent to academia and provide a supportive team to navigate the path toward a successful career. Scholarly productivity accreditation requirements are challenging, especially for new faculty with primary teaching responsibilities or those without an academic doctoral degree. Evidence suggests that network connections can improve faculty performance, innovation and retention. This study arose from concerns in recent years related to …

Who's In The Inner Circle? Exploring Network Connections Among Health Professions Faculty For Career Advancement, Maureen Becker, Elsie Wordekemper, Betsy J. Becker

Posters and Presentations: Physical Therapy

Purpose/Hypothesis

The purpose of this study is to explore the meaning of network connections in new or early career health professional faculty. Knowing this information can foster targeted faculty development strategies to build, leverage and maintain connections for advancement with scholarly activity. Faculty shortages currently exist amongst the medical and healthcare professions compounded by an aging U.S. population, increasing the demand for health care services.1 Each year, new faculty are hired, following carefully executed and costly searches. Much time, energy and finances are invested into "human" resources, not limited to, but including; salary, benefits and start up packages. All of …

Impediments To The Historical Development Of The Clinical Pap Test In The United States: Their Relevance In Optimizing Cervical Cancer Screening In The State Of Qatar, Nikolaos Chantziantoniou

Theses & Dissertations

Three hundred surveys listing 31 questions were distributed amongst women and men at Sidra Medicine, Doha, State of Qatar, to assess knowledge and perceptions of: Cervical cancer (CxCa); preventive Pap test screening; Human Papilloma Virus (HPV) vaccination; and, need for population-based screening. Survey questions captured categorical statistical data through four categories: (1) Socio-demographic; (2) Healthcare Services; (3) Health Literacy; and, (4) Self-efficacy and Perceptions. Hypothesis 1: 12 survey questions pertaining to CxCa and Pap testing revealed 8 statistically-significant dependencies; notably, 70% of respondents were aware of CxCa; however, 31.8% were unaware that CxCa may be curable; 33.7% were unaware …

The Effectiveness Of Registered Dietitians In Diabetes Case Management, Meghan C. Mclarney

Theses & Dissertations

OBJECTIVE: The objective of this paper is to investigate the effectiveness of diabetes education provided by registered dietitians (RD) in a diabetes case management (DCMs) model, compared to diabetes education provided by RDs in the usual care model (UCM) at an outpatient endocrinology clinic in Omaha, Nebraska. This study hypothesizes that education by RD DCMs will be equal or more efficacious in regards to primary outcomes of A1C and BMI and secondarily, lipid results and adherence (total encounters) when compared to outcomes of UC.

METHODS: This is a cross sectional retrospective review of patients with diabetes (n=946), receiving traditional RD …

Maternal Cognitions And The Origins Of Early Sensorimotor Based Play In Infants Born Preterm, Sandra L. Willett

Theses & Dissertations

Maternal cognitions are beliefs, perceptions, and expectations that guide parenting practices. For at-risk infants born prematurely, these maternal constructs may influence the caregiving environment and opportunities for motor experience. The impact of maternal cognitions on motor development in infants born preterm is not well-documented. This three-part dissertation systematically explores: 1) the nature and extent of existing evidence supporting the link between maternal cognitions and motor development of infants born preterm, 2) if maternal perception of infant vulnerability as measured by an adapted Vulnerable Baby Scale (VBS) can be validly and reliably quantified in mothers of infants born preterm and near …

Improving Internal Reliability Of A Trauma-Informed Care Program Evaluation Instrument, Ashley A. Raposo-Hadley

Capstone Experience

The project has analyzed the recent changes to the trauma-informed care (TIC) curriculum evaluation instrument by assessing the changes in Cronbach’s Alpha scores and effect significance. Data was collected from pre-training and post-training surveys completed at the time of delivery of the TIC curriculum training. Participants included hospital staff and medical or nursing students at Nebraska Medicine, University of Nebraska Medicine Center, and Health Creighton University Medical Center. The three research questions are (1) Did the item edits change item subgroupings? (2) Did the item edits increase instrument reliability? (3) Did the item edits impact statistical significance? 3 subscales, working …

The Lived Experience Of Psychological Occupational Stress In Early Childhood Education, Brooke Fletcher

Capstone Experience

Early childhood education (ECE) programs have been recognized by the Institute of Medicine and the Administration for Children and Families as excellent interventions to alleviate the long-term negative effects of poverty in the United States, but the quality of intervention provided and outcomes for the target population are adversely hindered by high occupational stress burdens for ECE teachers. According to Sheridan, Edwards, Marvin, and Knoche, the models used to address this concern are not empirically supported for specific applicability to ECE nonprofit settings. There is a need for deeper understanding of the lived experiences of ECE teachers, including the psychological …

Access To Care And Melanoma Incidence And Mortality In Nebraska, Natalia Trinidad

Capstone Experience

The purpose of this study is to determine incidence and mortality of melanoma across all counties in Nebraska in the context of access to primary care providers and dermatologists. Crude and age-adjusted incidence rates of melanoma from 2001-2016 by county were calculated for the following year intervals: 2001-2005, 2006-2010, 2011-2016. Variables for melanoma cases were obtained from the Nebraska Cancer Registry and included the case’s zip code at diagnosis, race, ethnicity, sex, age at diagnosis, year, cancer site, vital status, stage of disease, and the ICD-O code for the cancer type. Crude and age-adjusted mortality rates were calculated for the …

Association Of Copy Number Variations With Chronic Hepatitis B In Chinese Population, Fang Niu

Capstone Experience

With one third of the Hepatitis B virus (HBV) infection population of the world, chronic Hepatitis B (CHB) has become a top burden in China. CHB is a lifelong infection with HBV which can cause serious health problems, like cirrhosis, liver cancer or even death. HBV infection is known to result in various clinical conditions, including asymptomatic HBV carriers to chronic hepatitis and primary hepatocellular carcinoma. Several studies have shown that host genetic susceptibility could be an important factor that determines these various outcomes of HBV infection. Many Single Nucleotide Polymorphisms (SNPs) and Copy Number Variations (CNVs) have been associated …