Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 16 of 16

Full-Text Articles in Entire DC Network

Healthnet News V.21:No.3 Fall 2006, Judith S. Kronick, Alberta Richetelle Oct 2006

Healthnet News V.21:No.3 Fall 2006, Judith S. Kronick, Alberta Richetelle

Articles - Patient Care

A newsletter for public librarians and others interested in consumer health information services.


Preventing Back Pain In Horses, Jenifer Nadeau Sep 2006

Preventing Back Pain In Horses, Jenifer Nadeau

Extension Articles

Back pain is a source of poor performance and many different types of horses suffer from back problems. Early recognition of back pain is important, since damage may be cumulative. This information is provided to help horse owners and riders prevent, recognize, and pursue treatment for back pain in their horses.


An Integral Philosophy And Definition Of Nursing: Implications For A Unifying Meta-Theory Of Nursing, Olga F. Jarrin Sep 2006

An Integral Philosophy And Definition Of Nursing: Implications For A Unifying Meta-Theory Of Nursing, Olga F. Jarrin

School of Nursing Scholarly Works

A unifying meta-theory of nursing is suggested, building from the foundation of Ken Wilber’s AQAL (integral) framework. A definition of nursing as situated caring is presented. Historical discussion of contemporary nursing epistemology and theory are provided for context. Implications for practice, education, and research are discussed. A unifying meta-theory of nursing is needed to most benefit from the diversity in nursing education, practice, theory and research. A unifying meta-theory will enable nurses at both the practical and academic levels to appreciate the complexity and simplicity of nursing, allowing them to articulate confidently what we do and why we do it.


Healthnet News V.21:No.2 Summer 2006, Judith S. Kronick, Alberta Richetelle Jul 2006

Healthnet News V.21:No.2 Summer 2006, Judith S. Kronick, Alberta Richetelle

Articles - Patient Care

A newsletter for public librarians and others interested in consumer health information services.


Epigenetic Alterations In Rassf1a In Human Aberrant Crypt Foci, Emily J. Greenspan, Melissa A. Jablonski, Thiruchandurai V. Rajan, Joel Levine, Glenn S. Belinsky, Daniel W. Rosenberg Jul 2006

Epigenetic Alterations In Rassf1a In Human Aberrant Crypt Foci, Emily J. Greenspan, Melissa A. Jablonski, Thiruchandurai V. Rajan, Joel Levine, Glenn S. Belinsky, Daniel W. Rosenberg

UCHC Articles - Research

CpG island methylation (CIM) is an epigenetic mechanism for transcriptional silencing that occurs at various stages of colon tumorigenesis. CIM has been found in serrated adenomas and hyperplastic polyps. There is also evidence for hypermethylation in aberrant crypt foci (ACF) that are found in resected colons from cancer patients. Our study addresses promoter methylation of a tumor suppressor gene, RASSF1A, within the colonic epithelium of subjects undergoing screening colonoscopies in the absence of synchronous tumors. Patients included in this study were at elevated risk for colorectal cancer (CRC) based on family history, but without a previously occurring or synchronous …


Recruitment Of Men Into Nursing: Changing Attitudes, Nicklos M. Markey May 2006

Recruitment Of Men Into Nursing: Changing Attitudes, Nicklos M. Markey

School of Nursing Scholarly Works

No abstract provided.


In Vitro Expression And Purification Of Class I Mhc Molecules, Loi Cheng May 2006

In Vitro Expression And Purification Of Class I Mhc Molecules, Loi Cheng

Honors Scholar Theses

The major histocompatibility complex (MHC) is a gene family responsible for many critical functions of the immune system in most vertebrates. The MHC consists of three classes differentiated by their structure and function, and MHC class I encodes antigen binding proteins as well as chaperone and accessory proteins such as tapasin. The purpose of this project is to reconstitute several human MHC class I molecules in their peptide-filled and peptide-deficient forms, and to purify these proteins for biochemical study. The expressed proteins include wild type and mutant variants of the fusion protein human leukocyte antigen HLA-B*0801-fos, and human beta-2-microglobulin (β2m). …


Orthogonal Activation Of The Reengineered A3 Adenosine Receptor (Neoceptor) Using Tailored Nucleoside Agonists, Tatiana Sonin, Bruce T. Liang May 2006

Orthogonal Activation Of The Reengineered A3 Adenosine Receptor (Neoceptor) Using Tailored Nucleoside Agonists, Tatiana Sonin, Bruce T. Liang

UCHC Articles - Research

An alternative approach to overcome the inherent lack of specificity of conventional agonist therapy can be the reengineering of the GPCRs and their agonists. A reengineered receptor (neoceptor) could be selectively activated by a modified agonist, but not by the endogenous agonist. Assisted by rhodopsin-based molecular modeling, we pinpointed mutations of the A3 adenosine receptor (AR) for selective affinity enhancement following complementary modifications of adenosine. Ribose modifications examined included, at 3′: amino, aminomethyl, azido, guanidino, ureido; and at 5′: uronamido, azidodeoxy. N6-variations included: 3-iodobenzyl, 5-chloro-2-methyloxybenzyl, and methyl. An N6-3-iodobenzyl-3′-ureido adenosine derivative 10 activated phospholipase C …


Healthnet News V.21:No.1 Spring 2006, Judith S. Kronick, Alberta Richetelle Apr 2006

Healthnet News V.21:No.1 Spring 2006, Judith S. Kronick, Alberta Richetelle

Articles - Patient Care

A newsletter for public librarians and others interested in consumer health information services.


Medication Safety : Prevention Of Medication Errors Mar 2006

Medication Safety : Prevention Of Medication Errors

Articles - Patient Care

2006 National Patient Safety Goal: Reducing Medication Errors Prevention of medication errors is one of our most important goals as we move toward becoming the safest hospital in Connecticut. To prevent possible errors, we will use a process called “medication reconciliation.”


Association Between Two Μ-Opioid Receptor Gene (Oprm1) Haplotype Blocks And Drug Or Alcohol Dependence, Henry R. Kranzler Mar 2006

Association Between Two Μ-Opioid Receptor Gene (Oprm1) Haplotype Blocks And Drug Or Alcohol Dependence, Henry R. Kranzler

UCHC Articles - Research

We examined 13 single nucleotide polymorphisms (SNPs) spanning the coding region of the μ-opioid receptor gene (OPRM1), among 382 European Americans (EAs) affected with substance dependence [alcohol dependence (AD) and/or drug dependence (DD)] and 338 EA healthy controls. These SNPs delineated two haplotype blocks. Genotype distributions for all SNPs were in Hardy–Weinberg equilibrium (HWE) in controls, but in cases, four SNPs in Block I and three SNPs in Block II showed deviation from HWE. Significant differences were found between cases and controls in allele and/or genotype frequencies for six SNPs in Block I and two SNPs in Block …


Healthnet News V.21:No.4 Winter 2006, Judith S. Kronick, Alberta Richetelle Jan 2006

Healthnet News V.21:No.4 Winter 2006, Judith S. Kronick, Alberta Richetelle

Articles - Patient Care

A newsletter for public librarians and others interested in consumer health information services.


Ayurvedic Concept Of Food And Nutrition, Amala Guha Jan 2006

Ayurvedic Concept Of Food And Nutrition, Amala Guha

SoM Articles

Ayurveda places special emphasis on Ahar (diet) and Anna (food) and believes that healthy nutrition nourishes the mind, body and soul. Ayurveda does not discriminate food to be good, or bad, instead it emphasizes various factors that influence food, such as its biological properties, origin, environmental factors, seasons, preparation, freshness, and provides a logical explanation of how to balance food according to one's dosha and physical needs.


Neuroimmune Interactions: A Bidirectional Flow That Leads To Health And Disease, Robert E. Cone Jan 2006

Neuroimmune Interactions: A Bidirectional Flow That Leads To Health And Disease, Robert E. Cone

SoM Articles

The Vedic philosophy deals with harmony and balance between the mind and the body as well as interactions with nature. This ancient approach to health and well-being is being more and more appreciated in part as we understand the intimate relationship between the immune system, our major defense mechanism and the nervous system. Like other organ systems, the immune system is dependent on the central nervous system (CNS) and the endocrine system in its role for effective defense against foreign and domestic invaders.


2006, Kathe Gable Jan 2006

2006, Kathe Gable

UNISON

No abstract provided.


Annual Report Clinical Operations 2005/2006 Jan 2006

Annual Report Clinical Operations 2005/2006

Annual Reports - Patient Care

The clinical arm of the UConn Health Center consists of the UConn Medical (UMG), our physician faculty practice, the John Dempsey Hospital (JDH) and the Correctional Managed Health Care Program (CMHC). This 2006 Clinical Annual Report was issued Sept.1, 2006 by Steven Strongwater, MD, Director of Clinical Operations.