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Medicine and Health Sciences

University of Alabama at Birmingham

Pregnancy

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Provider Perspectives On Fertility And Fertility Preservation Discussions Among Women With Cystic Fibrosis, Jessica Corcoran, Caitlyn Campbell, Sigrid Ladores Jan 2023

Provider Perspectives On Fertility And Fertility Preservation Discussions Among Women With Cystic Fibrosis, Jessica Corcoran, Caitlyn Campbell, Sigrid Ladores

APC Fund

Cystic Fibrosis (CF) is a genetic disorder that primarily impacts the respiratory and gastrointestinal systems. With advances in treatment and medications, the life expectancy of people with CF is continuing to increase with current life expectancy at 47 years of age. Given the increased life expectancy, people with CF are interested in childbearing but may have CF specific fertility issues that should be addressed by their CF healthcare provider. Currently, these conversations are not occurring or are suboptimal. This study aimed to investigate the practices of cystic fibrosis (CF) healthcare providers regarding fertility and fertility preservation (FP) discussions among women …


Challenges And Promising Strategies For Maximizing Pregnant Women's Adherence And Retention In Niv Care In The Context Of Option B+ In Kenya, Anna Helova Jan 2020

Challenges And Promising Strategies For Maximizing Pregnant Women's Adherence And Retention In Niv Care In The Context Of Option B+ In Kenya, Anna Helova

All ETDs from UAB

Under the current Kenyan guidelines, pregnant/postpartum women who test HIV-positive are immediately put on the lifelong antiretroviral (ART) therapy (Option B+) and are initiated into the prevention of mother-to-child (PMTCT) protocol. Gaps at each step of the PMTCT continuum undermine the positive impact of lifelong ART. Challenges at the individual, interpersonal, community, and health facility-levels contribute to these gaps. A community-based mentor mother (cMM) program tested under the Mother-Infant Visit Adherence and Treatment Engagement(MOTIVATE!) Trial (NICHD R01 R01HD080477; ClinicalTrials.gov#14-0331) is a potential approach to address these challenges. The three manuscripts comprising this dissertation used qualitative and quantitative methods with the …


Formaldehyde Exposure In Pregnant Women And Its Relationship To Fetal Growth, Azita Amiri Jan 2014

Formaldehyde Exposure In Pregnant Women And Its Relationship To Fetal Growth, Azita Amiri

All ETDs from UAB

Formaldehyde exposure during pregnancy has been linked to adverse pregnancy outcomes such as poor fetal growth, although few studies have examined formaldehyde exposure during pregnancy and its relationship to fetal growth. The purpose of this study was to determine the level of formaldehyde exposure during pregnancy and examine the relationship between formaldehyde exposure and fetal growth. Formaldehyde exposure was examined, using vapor monitor badge and urine formic acid, in 140 women in their second trimester of pregnancy. One time urine samples were collected during a routine prenatal visit, and women wore the vapor badges for 24 hours. Fetal growth was …


The Effect Of An Intensive Oral Hygiene Regimen On Gingival Inflammation During Pregnancy: Clinical And Laboratory Analysis, Maninder Kaur Jan 2013

The Effect Of An Intensive Oral Hygiene Regimen On Gingival Inflammation During Pregnancy: Clinical And Laboratory Analysis, Maninder Kaur

All ETDs from UAB

Background: Recent evidence suggests that systemic inflammation as host immune response to oral microbial challenge may well underlie the observed association between periodontal disease and preterm birth/low birth weight (PTB/LBW). The aim of this pilot study was to evaluate the effect of vigorous oral hygiene regimen on gingival inflammation and gingival crevicular fluid (GCF)/serum biomarkers (TNF-&alpha, IL-1&beta and IL-6) during pregnancy and its impact on pregnancy outcome. Methods: 120 participants with pregnancy between 16-24 weeks gestation and with gingival index (GI) scores &ge 2 at &ge 50 % of tooth sites were recruited from the available pool of patients at …


Hard On Your Heart: A Qualitative Description Of Adolescent Prenatal Stress, Candace Clayton Knight Jan 2013

Hard On Your Heart: A Qualitative Description Of Adolescent Prenatal Stress, Candace Clayton Knight

All ETDs from UAB

Introduction: Pregnancy during adolescence is potentially stressful due to the concurrent tasks of navigating the typically tumultuous adolescent stage of development and the life altering experience of pregnancy (Kaye, 2008). There is a growing body of research linking prenatal stress to poor birth and developmental outcomes such as premature birth and low birth weight infants (K. Keenan, Sheffield, & Boeldt, 2007; Mulder et al., 2002), which makes describing the relatively unexplored perceptions and experience of stress during adolescent pregnancy important. The life course framework, with its emphasis on social, environmental, and family risk factors, has implications for reducing disparities among …


Association Between Birth Outcomes And Aflatoxin B1-Biomarker Levels Among Pregnant Women In Kumasi, Ghana, Faisal Mohammed Barbas Shuaib Jan 2010

Association Between Birth Outcomes And Aflatoxin B1-Biomarker Levels Among Pregnant Women In Kumasi, Ghana, Faisal Mohammed Barbas Shuaib

All ETDs from UAB

Aflatoxins are fungal metabolites that contaminate staple food crops in many developing countries. Although studies have linked these toxins to adverse health outcomes, few studies have investigated the association between birth outcomes and aflatoxin B1-lysine adduct levels among pregnant women. The objective of this dissertation was to investigate the association between birth outcomes and aflatoxin B1- lysine adduct levels among pregnant women in Kumasi, Ghana. In a cross-sectional study of 755 pregnant women, Aflatoxin B1-lysine adduct (AF-ALB) levels were determined by High Performance Liquid Chromatography. AF-ALB associations were assessed as both continuous and categorical values. Analysis of variance (ANOVA) was …