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Development And Validation Of A Direct Tibial Loading Device For Mice, Sylvie Kalikoff
Development And Validation Of A Direct Tibial Loading Device For Mice, Sylvie Kalikoff
Honors Theses
Of the six million bones fractured each year in the United States, 5 to 10% do not heal properly. Fractures range in severity and classification, and are therefore treated differently depending on the type of bone that was broken, the location of the break, and the way in which the specific bone regrows. It is crucial that the appropriate treatment be carried out in order to properly heal the broken bone.
The Optimization Of Porosity And Pore Patterning For Patient-Specific Ti-6 Al-4v Femur Implants, Stephen Paolicelli
The Optimization Of Porosity And Pore Patterning For Patient-Specific Ti-6 Al-4v Femur Implants, Stephen Paolicelli
Honors Theses
Metastatic bone cancer often arises in the long bones of the body. Taking a patient specific approach by utilizing a customized implant is a superior method of treatment compared to today’s solutions, which often includes amputation. A titanium-alloy femur implant has been optimized by varying pore size, pore pattern, and porosity in order to maximize osseointegration. By maximizing osseointegration, the implant will remain firmly in place for a longer period of time because bone will grow throughout the implant, securing it. In addition, it is important for the bone to behave mechanically like bone. This requires the global elastic modulus …
The Design Of Patient-Specific Implants To Treat Bone Cancer, Shelby Marks
The Design Of Patient-Specific Implants To Treat Bone Cancer, Shelby Marks
Honors Theses
Benign and malignant tumors often arise in bone due to metastasizing cancer. Thirty years ago limbs affected by tumors were treated with amputation, now with new technology, limb‐saving surgery is used most of the time; however, these surgical methods have limitations. Research shows a trend of using allografts and metallic implants to fill the bone gap once the tumor is resected. In some cases sections up to one third of the femur can be removed, sometimes disrupting the joint. There are many problems such as the integration and risk of failure in these implants. A more patient specific approach can …