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A Differential Response To Antihypertensive Therapy In African Men And Women: Insights From The Creole Trial, Dike B. Ojji, Gabriel L. Shedul, Mahmoud Sani, Okechukwu S. Ogah, Anastase Dzudie, Felix Barasa, Charles Mondo, Prossie M. Ingabire, Erika S.W. Jones, Brian Rayner, Damasceno Albertino, Elijah Ogola, Wynand Smythe, Nicky Hickman, Veronica Francis, Pandie Shahiemah, Grace Shedul, Akinyemi Aje, Karen Sliwa, Simon Stewart, For The Creole Investigators
A Differential Response To Antihypertensive Therapy In African Men And Women: Insights From The Creole Trial, Dike B. Ojji, Gabriel L. Shedul, Mahmoud Sani, Okechukwu S. Ogah, Anastase Dzudie, Felix Barasa, Charles Mondo, Prossie M. Ingabire, Erika S.W. Jones, Brian Rayner, Damasceno Albertino, Elijah Ogola, Wynand Smythe, Nicky Hickman, Veronica Francis, Pandie Shahiemah, Grace Shedul, Akinyemi Aje, Karen Sliwa, Simon Stewart, For The Creole Investigators
IHR Papers and Journal Articles
Background: We sought to address the paucity of data to support the evidence-based management of hypertension to achieve optimal blood pressure (BP) control on a sex-specific basis in Africa.
Methods: We undertook a post hoc analysis of the multicenter, randomized CREOLE (Comparison of Three Combination Therapies in Lowering Blood Pressure in Black Africans) Trial to test the hypothesis that there would be clinically important differences in office BP control between African men and women. We compared the BP levels of 397 and 238 hypertensive women (63%, 50.9 ± 10.5 years) and men (51.2 ± 11.3 years) from 10 sites across …